Abstract: Disclosed are small molecule antagonists of ?4?7 integrin, and methods of using them to treat a number of specific diseases or conditions.

Abstract: The invention discloses a high voltage rechargeable Zn—MnO2 battery. The structure of the Zn—MnO2 battery includes zinc electrode/alkaline electrolyte/ion exchange membrane/acid electrolyte/MnO2 electrode. The ion exchange membrane comprises a cation exchange membrane, an anion exchange membrane or a proton exchange membrane. According to the invention, by using a composite electrolyte system (alkaline electrolyte/ion exchange membrane/acid electrolyte), a high voltage rechargeable Zn—MnO2 battery is obtained. According to the invention, an open circuit voltage of up to 2.7V is obtained, greatly improving the discharge voltage, and at the same time increasing the discharge capacity and enabling cyclic charge and discharge. The invention is of great importance in science research, beneficial to society and economics.

Abstract: Disclosed are small molecule antagonists of human ?4?7 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: The invention discloses a high voltage rechargeable Zn—MnO2 battery. The structure of the Zn—MnO2 battery includes zinc electrode/alkaline electrolyte/ion exchange membrane/acid electrolyte/MnO2 electrode. The ion exchange membrane comprises a cation exchange membrane, an anion exchange membrane or a proton exchange membrane. According to the invention, by using a composite electrolyte system (alkaline electrolyte/ion exchange membrane/acid electrolyte), a high voltage rechargeable Zn—MnO2 battery is obtained. According to the invention, an open circuit voltage of up to 2.7V is obtained, greatly improving the discharge voltage, and at the same time increasing the discharge capacity and enabling cyclic charge and discharge. The invention is of great importance in science research, beneficial to society and economics.

Abstract: Disclosed are small molecule antagonists of ?4?7 integrin, and methods of using them to treat a number of specific diseases or conditions.

Abstract: Disclosed are small molecule antagonists of human ?4?7 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: The present disclosure provides pladienolide compounds, pharmaceutical compositions containing such compounds, and pladienolide compounds for use in methods of medical treatment. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are pladienolide compounds for use in methods of treating cancers by administering at least one pladienolide compound disclosed herein and at least one additional therapy.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: The disclosure provides a preparation method for a novel biocompatible antibacterial bacterial cellulose Fmoc-F hydrogel, belonging to the technical field of biomedical gels. The preparation method is characterized by comprising the following steps of (1) preparing a bacterial cellulose (BC) homogenate, (2) mixing the bacterial cellulose with an Fmoc-F solution, and preparing the bacterial cellulose/Fmoc-F antibacterial hydrogel by means of in-situ chemical crosslinking. The preparation method has the advantages of rapid gelling reaction, simple reaction system, high gel plasticity and the like. Because of the bacterial cellulose, the antibacterial hydrogel prepared in the disclosure has high mechanical strength. Meanwhile, compared with traditional micro-molecular antibacterial materials, the bacterial cellulose/Fmoc-F antibacterial hydrogels prepared in the disclosure have broad-spectrum antibacterial effects and good biocompatibility.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed are small molecule antagonists of ?4?7 integrin, and methods of using them to treat a number of specific diseases or conditions.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed are small molecule antagonists of ?4?7 integrin, and methods of using them to treat a number of specific diseases or conditions.

Abstract: The present invention discloses a novel nano-composite antibacterial material and a preparation method and an application thereof, and belongs to the technical field of preservative materials. The novel nano-composite antibacterial material disclosed by the present invention is prepared by mixing a dimethylimidazole solution, deionized water and a zinc nitrate solution to prepare a metal-organic framework carrier, compositing with nisin to form a nano antibacterial composite material, separating out from a solution in a precipitate form, centrifuging, removing a supernatant, cleaning and re-suspending with the deionized water. The novel nano-composite antibacterial material prepared by the present invention has an antibacterial effect superior to nisin having a same concentration.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: An electronic device includes a receiver sense circuit configured to generate a detection signal responsive to detecting a connection to a sink device via a connector. The electronic device further includes a controller coupled to a hot plug detect (HPD) interface. The controller is configured to enable a direct current (DC) voltage source based on the detection signal received from the receiver sense circuit.

Abstract: Disclosed are small molecule antagonists of ?4?7 integrin, and methods of using them to treat a number of specific diseases or conditions.

Abstract: The present invention discloses a method for lightning stroke identification and location on optical fiber composite overhead ground wire. In the method, according to the property that the lightning stroke will cause a sudden temperature rise at the lightning stroke position on the optical fiber composite overhead ground wire, optical fiber resources in the optical fiber composite overhead ground wire and the high-sensitivity detection and high-precision event locating capability of a distributed optical fiber temperature sensor can be fully utilized.

Abstract: The present disclosure is directed to formulations comprising (1) at least one formulation transport agent, (2) at least one complexing agent, and (3) at least one active agent that modulates one or more traits of a target insect, plant, or plant pathogen. The present disclosure is also directed to methods of delivering such formulations to the target organism, as well as to formulation transport agents used to prepare such formulations.