Patents by Inventor Chi-Tang Ho

Chi-Tang Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7201928
    Abstract: Compositions and methods of inhibiting tumor cell growth and treating and preventing cancer are provided based on administration of an orange peel extract either alone or in combination with other phytochemicals.
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: April 10, 2007
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Mou Tuan Huang, Chi-Tang Ho, Robert T. Rosen, Geetha Ghai, Martin Lipkin, Kuang Yu Chen, Nitin Telang, Charles Boyd, Katalin Csiszar
  • Publication number: 20060241154
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Application
    Filed: June 23, 2006
    Publication date: October 26, 2006
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert Rosen, Slavik Dushenkov
  • Patent number: 7087790
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: August 8, 2006
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert T. Rosen, Slavik Dushenkov
  • Publication number: 20060052438
    Abstract: In one aspect, the present invention provides compounds having formula I or IV as shown below: as further defined herein. In additional aspects, the present invention provides compositions and kits comprising the compounds of the invention and methods for their use, for example, for the prevention or treatment of a cancer.
    Type: Application
    Filed: April 29, 2005
    Publication date: March 9, 2006
    Inventors: Chi-Tang Ho, Naisheng Bai, Zigang Dong, Ann Bode, Slavik Dushenkov
  • Publication number: 20050215635
    Abstract: The present invention relates to diarylheptanoid compounds and compositions comprising a diarylheptanoid compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering to a subject in need thereof one or more diarylheptanoid compounds. In particular, the invention relates to methods for preventing or treating cancer or an inflammatory disorder by administering to a subject in need thereof one or more diarylheptanoid compounds. The present invention further relates to articles of manufacture comprising one or more diarylheptanoid compounds.
    Type: Application
    Filed: March 8, 2005
    Publication date: September 29, 2005
    Inventors: M. Mohamed Rafi, Zhihua Liu, Robert Rosen, Sharon Rosen, Chi-Tang Ho
  • Publication number: 20050049284
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 3, 2005
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert Rosen, Slavik Dushenkov
  • Publication number: 20040224034
    Abstract: Compositions and methods for preventing and treating disease are provided. The compositions are extracts of black tea that include a mixture of theaflavin-3-gallate and theaflavin-3′-gallate.
    Type: Application
    Filed: June 17, 2004
    Publication date: November 11, 2004
    Inventors: Kuang Yu Chen, Chi-Tang Ho, Robert T. Rosen, Geetha Ghai
  • Publication number: 20040052881
    Abstract: Compositions and methods for preventing and treating cancer are provided that comprise extracts of Inula britannica or compounds isolated therefrom.
    Type: Application
    Filed: September 15, 2003
    Publication date: March 18, 2004
    Inventors: Chi-Tang Ho, Mohammed Rafi, Robert S. DiPaola, Geetha Ghai, Robert T. Rosen, Naisheng Bai
  • Patent number: 6627623
    Abstract: Compositions and methods for preventing and treating cancer are provided that comprise extracts of Inula britannica or compounds isolated therefrom. The compounds of 1-O-acetylbritannilactone or 1,6-O,O-diacetylbritannilactone are isolated and used for inducing apoptosis in cells and for treating cancer in an animal. Induction of apoptosis comprises contacting cells with a composition comprising the compounds in an amount sufficient to induce Bcl-2 protein phosphorylation. Further, treatment of cancer in an animal comprises administering to an animal a composition comprising the compounds in an amount sufficient to induce Bcl-2 protein phosphorylation to treat the cancer.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: September 30, 2003
    Assignee: Rutgers, the State University
    Inventors: Chi-Tang Ho, Mohammed Rafi, Robert S. Dipaola, Geetha Ghai, Robert T. Rosen, Naisheng Bai
  • Publication number: 20030004116
    Abstract: Compositions are provided which are derived from extracting the pulp of Noni fruit with butanol. The butanol extract of Noni fruit contains active glycoside compounds which are useful in the prevention and treatment of disease.
    Type: Application
    Filed: May 17, 2002
    Publication date: January 2, 2003
    Inventors: Gheetha Ghai, Chi-Tang Ho, Robert T. Rosen, Mingfu Wang, Charles D. Boyd, Katalin Csiszar
  • Patent number: 6498195
    Abstract: Compositions and methods are provided for prevention and treatment of cancer. The compositions comprise pure hydroxylated chalcone compounds of licorice root (Glycyrrhiza glabra) including 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4′-hydroxyphenyl).
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: December 24, 2002
    Assignees: Rutgers, The State University of New Jersey, University of Medicine and Dentistry of New Jersey
    Inventors: Robert T. Rosen, Chi-Tang Ho, Robert S. DiPaola, Mohamed M. Rafi, Bret C. Vastano, Geetha Ghai
  • Publication number: 20020155178
    Abstract: Compositions and methods for preventing and treating cancer are provided that comprise extracts of Inula britannica or compounds isolated therefrom.
    Type: Application
    Filed: February 20, 2002
    Publication date: October 24, 2002
    Inventors: Chi-Tang Ho, Mohammed Rafi, Robert S. DiPaola, Geetha Ghai, Robert T. Rosen, Naisheng Bai
  • Publication number: 20020146472
    Abstract: Compositions and methods for preventing and treating disease are provided. The compositions are extracts of black tea that include a mixture of theaflavin-3-gallate and theaflavin-3′-gallate.
    Type: Application
    Filed: November 14, 2001
    Publication date: October 10, 2002
    Inventors: Kuang Yu Chen, Chi-Tang Ho, Robert T. Rosen, Geetha Ghai
  • Publication number: 20020028852
    Abstract: Compositions and methods for prevention or treatment of disease are provided which comprise analogs of Resveratrol.
    Type: Application
    Filed: May 18, 2001
    Publication date: March 7, 2002
    Inventors: Geetha Ghai, Kuang Yu Chen, Robert T. Rosen, Mingfu Wang, Nitin Telang, Martin Lipkin, Chi-Tang Ho
  • Publication number: 20020022665
    Abstract: Compositions and methods are provided for prevention and treatment of cancer. The compositions comprise pure hydroxylated chalcone compounds of licorice root (Glycyrrhiza glabra) including 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4′-hydroxyphenyl).
    Type: Application
    Filed: June 13, 2001
    Publication date: February 21, 2002
    Inventors: Robert T. Rosen, Chi-Tang Ho, Robert S. DiPaola, Mohamed M. Rafi, Bret C. Vastano, Geetha Ghai
  • Patent number: 5955269
    Abstract: The invention relates to an assay system for screening nutraceuticals, i.e., foods or food substances that occur naturally, or that are produced during processing which are capable of modulating in a subject the expression of one or more genes associated with a disease or undesirable physical condition. The nutraceuticals identified by the screening assays can be incorporated into compositions which may be administered to a subject to treat or prevent a disease or undesirable condition, or otherwise to improve the health of the subject. The invention further provides methods for modifying the amount of nutraceuticals in raw and processed foods or food substances.
    Type: Grant
    Filed: June 20, 1996
    Date of Patent: September 21, 1999
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Geetha Ghai, Charles Boyd, Katalin Csiszar, Chi-Tang Ho, Robert T. Rosen
  • Patent number: 4670267
    Abstract: A butter flavoring composition is prepared by fermenting a sweet-whey medium. The sweet-whey medium comprises water, sweet-whey solids, a biosynthesis-precursor-compound fortifier, and a fatty-compound enriching agent. The sweet-whey medium is pasteurized and then innoculated with a microorganism culture comprising the microorganism Leuconostoc cremoris. The innoculated medium is then incubated in a controlled temperature range with agitation and aeration to produce a fermented composition suitable for use as a butter flavoring.
    Type: Grant
    Filed: April 18, 1985
    Date of Patent: June 2, 1987
    Assignee: Lever Brothers Company
    Inventors: Stephen S. Chang, Chi-Tang Ho, Barbara A. Izzo
  • Patent number: 4638095
    Abstract: This disclosure describes the extraction of a novel antioxidant, Rosmaridiphenol, isolated from the leaves of Rosemary.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: January 20, 1987
    Assignee: Research Corporation
    Inventors: Stephen S. Chang, Chi-Tang Ho, Christopher M. Houlihan