Patents by Inventor Chien-Huang Wu

Chien-Huang Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230085362
    Abstract: Pyrimidine compounds of formula (I) shown herein. Also disclosed are pharmaceutical compositions containing one of the pyrimidine compounds and methods of using the pyrimidine compounds to treat or prevent chemotherapy-induced peripheral neuropathy.
    Type: Application
    Filed: July 29, 2022
    Publication date: March 16, 2023
    Inventors: Jang-Yang Chang, Meng-Ru Shen, Kak-Shan Shia, Chien-Huang Wu
  • Patent number: 10882854
    Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed is a pharmaceutical composition containing one of the heterocyclic compounds. Further disclosed are methods of using one of the heterocyclic compounds for mobilizing hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation, and for treating tissue injury, cancer, inflammatory disease, and autoimmune disease.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: January 5, 2021
    Assignee: National Health Research Institutes
    Inventors: Kak-Shan Shia, Chien-Huang Wu, Ming-Chen Chou, Jen-Shin Song, Yun Wang, Chuan Shih
  • Publication number: 20180208588
    Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed is a pharmaceutical composition containing one of the heterocyclic compounds. Further disclosed are methods of using one of the heterocyclic compounds for mobilizing hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation, and for treating tissue injury, cancer, inflammatory disease, and autoimmune disease.
    Type: Application
    Filed: January 8, 2018
    Publication date: July 26, 2018
    Inventors: Kak-Shan Shia, Chien-Huang Wu, Ming-Chen Chou, Jen-Shin Song, Yun Wang, Chuan Shih
  • Patent number: 9388193
    Abstract: Dipicolylamine compounds of Formula (I) set forth herein. Also disclosed are pharmaceutical compositions containing metal ions and these compounds. Further disclosed is a method for treating a condition associated with cells containing inside-out phosphatidylserine, with these compounds.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: July 12, 2016
    Assignees: National Health Research Institutes, Molecular Targeting Technologies, Inc.
    Inventors: Chiung-Tong Chen, Kak-Shan Shia, Chien-Huang Wu, Lun-Kelvin Tsou, Yu-Sheng Chao
  • Publication number: 20150336976
    Abstract: Dipicolylamine compounds of Formula (I) set forth herein. Also disclosed are pharmaceutical compositions containing metal ions and these compounds. Further disclosed is a method for treating a condition associated with cells containing inside-out phosphatidylserine, with these compounds.
    Type: Application
    Filed: May 14, 2015
    Publication date: November 26, 2015
    Inventors: Chiung-Tong Cheng, Kak-Shan Shia, Chien-Huang Wu, Lun-Kelvin Tsou, Yu-Sheng Chao
  • Patent number: 8354442
    Abstract: Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: January 15, 2013
    Assignee: National Health Research Institutes
    Inventors: Kak-Shan Shia, Chien-Huang Wu, Teng-Kuang Yeh, Yu-Sheng Chao
  • Patent number: 8193206
    Abstract: This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the specification.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: June 5, 2012
    Assignee: TaiGen Biotechnology Co., Ltd.
    Inventors: Chi-Feng Yen, Cheng-Kung Hu, Ming-Chen Chou, Chen-Tso Tseng, Chien-Huang Wu, Ying-Huey Huang, Shu-Jen Chen, Chi-Hsin Richard King
  • Patent number: 8026804
    Abstract: The apparatus is applicable to a communications network, wherein, via an information processing platform of a network server end, the system is connected to a network surveillance device installed in a monitored environment, in which the information processing platform processes and saves event message about the environment acquired by the network surveillance device, and generates corresponding notification messages. Via a browsing authorization certification mechanism, the system allows a user having been identified as a certified user to connect to the information processing platform via a communication terminal device for monitoring message information.
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: September 27, 2011
    Assignee: Chunghwa Telecom Co., Ltd.
    Inventors: Chien-Huang Wu, Show-Ling Wu, Jhao-Siang Sun, Lun-Hsing Yeh, Shu-Fang Xiao, Yu-Huan Wang
  • Publication number: 20110057787
    Abstract: A residential security surveillance and notification management system is provided according to the present invention. The system is applicable to a communications network, wherein, via an information processing platform of a network server end, the system is connected to a network surveillance device installed in a monitored environment, in which the information processing platform processes and saves event message about the environment acquired by the network surveillance device, and also generates corresponding notification messages. In addition, via a browsing authorization certification mechanism, the system allows a user who has been identified as a certified user to connect to the information processing platform via a communication terminal device for monitoring message information.
    Type: Application
    Filed: May 22, 2008
    Publication date: March 10, 2011
    Applicant: CHUNGHWA TELECOM CO., LTD.
    Inventors: Chien-Huang Wu, Show-Ling Wu, Jhao-Siang Sun, Lun-Hsing Yeh, Shu-Fang Xiao, Yu-Huan Wang
  • Publication number: 20100113546
    Abstract: Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 6, 2010
    Applicant: National Health Research Institutes
    Inventors: Kak-Shan Shia, Chien-Huang Wu, Teng-Kuang Yeh, Yu-Sheng Chao
  • Patent number: 7589197
    Abstract: This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the specification.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: September 15, 2009
    Assignee: Taigen Biotechnology
    Inventors: Chi-Feng Yen, Cheng-Kung Hu, Ming-Chen Chou, Chen-Tso Tseng, Chien-Huang Wu, Ying-Huey Huang, Shu-Jen Chen, Chi-Hsin Richard King
  • Publication number: 20090143302
    Abstract: This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the specification.
    Type: Application
    Filed: December 8, 2008
    Publication date: June 4, 2009
    Applicant: TaiGen Biotechnology Co., Ltd.
    Inventors: Chi-Feng Yen, Cheng-Kung Hu, Ming-Chen Chou, Chen-Tso Tseng, Chien-Huang Wu, Ying-Huey Huang, Shu-Jen Chen, Chi-Hsin Richard King
  • Patent number: 7504422
    Abstract: This invention relates to methods for treating retinopathy and repairing tissue damage. The methods include administering to a subject in need thereof an effective amount of one or more compounds of the following formula. Each variable in this formula is defined in the specification.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: March 17, 2009
    Assignee: Taigen Biotechnology Co. Ltd.
    Inventors: Chi-Feng Yen, Chi-Hsin Richard King, Hua-Chien Chen, Gholam Hossein Hakimelahi, Shu-Jen Chen, Ying-Huey Huang, Chien-Huang Wu
  • Patent number: 7501526
    Abstract: This invention relates to methods of preparing the compounds of formula (V): Each variable in this formula is defined in the specification.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: March 10, 2009
    Assignee: Taigen Biotechnology
    Inventors: Chien-Huang Wu, Jia-Liang Zhu, Chen-Tso Tseng, Chi-Feng Yen, Kak-Shan Shia, Yibin Xiang, Gholam Hossein Hakimelahi, Ming-Chen Chou
  • Publication number: 20080058382
    Abstract: This invention relates to methods for treating retinopathy and repairing tissue damage. The methods include administering to a subject in need thereof an effective amount of one or more compounds of the following formula. Each variable in this formula is defined in the specification.
    Type: Application
    Filed: August 6, 2007
    Publication date: March 6, 2008
    Applicant: TaiGen Biotechnology Co., Ltd.
    Inventors: Chi-Feng Yen, Chi-Hsin King, Hua-Chien Chen, Gholam Hakimelahi, Shu-Jen Chen, Ying-Huey Huang, Chien-Huang Wu
  • Publication number: 20060293324
    Abstract: This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the specification.
    Type: Application
    Filed: June 13, 2006
    Publication date: December 28, 2006
    Inventors: Chi-Feng Yen, Cheng-Kung Hu, Ming-Chen Chou, Chen-Tso Tseng, Chien-Huang Wu, Ying-Huey Huang, Shu-Jen Chen, Chi-Hsin King
  • Publication number: 20060281712
    Abstract: This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the specification.
    Type: Application
    Filed: June 13, 2006
    Publication date: December 14, 2006
    Inventors: Chi-Feng Yen, Cheng-Kung Hu, Ming-Chen Chou, Chen-Tso Tseng, Chien-Huang Wu, Ying-Huey Huang, Shu-Jen Chen, Chi-Hsin King
  • Publication number: 20060160860
    Abstract: This invention relates to methods of preparing the compounds of formula (V): Each variable in this formula is defined in the specification.
    Type: Application
    Filed: January 20, 2005
    Publication date: July 20, 2006
    Inventors: Chien-Huang Wu, Jia-Liang Zhu, Chen-Tso Tseng, Chi-Feng Yen, Kak-Shan Shia, Yibin Xiang, Gholam Hakimelahi, Ming-Chen Chou
  • Patent number: 6313338
    Abstract: A process for preparing N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride of the following formula (I), is to react N-[1-(S)-ethyoxy carbonyl-3-phenylpropyl]-L-alanine with XCOOR, wherein X is halogen atom, R is C1-C6 alkyl, to obtain a N-alkoxycarbonyl compound, then reacting with an acyl group activation reagent, finally contact with water. The compound of formula (I) is a key intermediate of ACE inhibitors.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: November 6, 2001
    Assignee: Everlight USA, Inc.
    Inventors: Chong-Ming Chen, Yu-Liang Liu, Ya-Chieh Chao, Chien-Huang Wu
  • Patent number: 6262274
    Abstract: A process for preparing N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride of the following formula (I), is to react N-[1 -(S)-ethyoxy carbonyl-3-phenylpropyl]-L-alanine with XCOOR, wherein X is halogen atom, R is C1-C6 alkyl, to obtain a N-alkoxycarbonyl compound, then reacting with an acyl group activation reagent, finally contact with water. The compound of formula (I) is a key intermediate of ACE inhibitors.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: July 17, 2001
    Assignee: Everlight USA, Inc.
    Inventors: Chong-Ming Chen, Yu-Liang Liu, Ya-Chieh Chao, Chien-Huang Wu