Patents by Inventor Chong-Hui Gu

Chong-Hui Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cocrystals, pharmaceutical compositions thereof, and methods of treatment involving same
    Patent number: 11851417
    Abstract: Provided are solid forms of a compound useful for treating cancer, pharmaceutical compositions thereof, and methods of treating cancer comprising administering the solid forms described herein to a patient in need thereof.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: December 26, 2023
    Assignee: Servier Pharmaceuticals LLC
    Inventors: Benjamin S. Lane, Chong-Hui Gu
  • Citrate salt, pharmaceutical compositions, and methods of making and using the same
    Patent number: 11767330
    Abstract: The present disclosure features citrate salts and pharmaceutical compositions useful for the treatment of BAF complex-related disorders. Also disclosed are methods for preparing compounds.
    Type: Grant
    Filed: July 6, 2022
    Date of Patent: September 26, 2023
    Assignee: FOGHORN THERAPEUTICS INC.
    Inventors: Chong-Hui Gu, Joshua D. Waetzig
  • Pharmaceutical composition and administrations thereof
    Patent number: 11752106
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Grant
    Filed: September 15, 2021
    Date of Patent: September 12, 2023
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni Dokou, Shahla Jamzad, John P. Caesar, Jr., Majed Fawaz, Laura Das, Chong-Hui Gu, Patricia Nell Hurter, Meghna Jai Israni, Meghan M. Johnston, Dragutin Knezic, Andrew G. Kuzmission, HongRen Wang
  • CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20230064136
    Abstract: The present disclosure features citrate salts and pharmaceutical compositions useful for the treatment of BAF complex-related disorders. Also disclosed are methods for preparing compounds.
    Type: Application
    Filed: July 6, 2022
    Publication date: March 2, 2023
    Inventors: Chong-Hui GU, Joshua D. WAETZIG
  • Pharmaceutical compositions of therapeutically active compounds
    Patent number: 11504361
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: November 22, 2022
    Assignee: SERVIER PHARMACEUTICALS LLC
    Inventor: Chong-Hui Gu
  • COCRYSTALS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF TREATMENT INVOLVING SAME
    Publication number: 20220363661
    Abstract: Provided are solid forms of a compound useful for treating cancer, pharmaceutical compositions thereof, and methods of treating cancer comprising administering the solid forms described herein to a patient in need thereof.
    Type: Application
    Filed: April 19, 2022
    Publication date: November 17, 2022
    Inventors: Benjamin S. Lane, Chong-Hui Gu
  • TABLET COMPOSITIONS
    Publication number: 20220323447
    Abstract: Provided herein is a tablet comprising 2-methyl-1-[(4-[-6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 21, 2022
    Publication date: October 13, 2022
    Inventors: Sreenivas S. Bhat, Scott Burnside, Darshan Parikh, Chong-Hui Gu, Syed Altaf
  • PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF
    Publication number: 20220241206
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Application
    Filed: September 15, 2021
    Publication date: August 4, 2022
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni DOKOU, Shahla JAMZAD, John P. CAESAR, JR., Majed FAWAZ, Laura DAS, Chong-Hui GU, Patricia Nell HURTER, Meghna Jai ISRANI, Meghan M. JOHNSTON, Dragutin KNEZIC, Andrew G. KUZMISSION, HongRen WANG
  • Tablet compositions
    Patent number: 11389454
    Abstract: Provided herein is a tablet comprising 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: July 19, 2022
    Assignees: CELGENE CORPORATION, SERVIER PHARMACEUTICALS LLC
    Inventors: Sreenivas S. Bhat, Scott Burnside, Darshan Parikh, Chong-Hui Gu, Syed Altaf
  • Cocrystals, pharmaceutical compositions thereof, and methods of treatment involving same
    Patent number: 11345677
    Abstract: Provided are solid forms of a compound useful for treating cancer, pharmaceutical compositions thereof, and methods of treating cancer comprising administering the solid forms described herein to a patient in need thereof.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: May 31, 2022
    Assignee: Servier Pharmaceuticals LLC
    Inventors: Benjamin S. Lane, Chong-Hui Gu
  • IVOSIDENIB FORMS AND PHARMACEUTICAL COMPOSITIONS
    Publication number: 20210323944
    Abstract: Provided are formulations of ivosidenib including a number of polymorphs. Further provided are formulations of ivosidenib containing a number of known impurities. Still further provided are stable compositions of ivosidenib.
    Type: Application
    Filed: July 2, 2019
    Publication date: October 21, 2021
    Applicant: AGIOS PHARMACEUTICALS, INC.
    Inventors: Chong-Hui GU, Jacob Paul SIZEMORE, Shijie ZHANG
  • Pharmaceutical composition and administrations thereof
    Patent number: 11147770
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: October 19, 2021
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni Dokou, Shahla Jamzad, John P. Caesar, Jr., Majed Fawaz, Laura Das, Chong-Hui Gu, Patricia Nell Hurter, Meghna Jai Israni, Meghan M. Johnston, Dragutin Knezic, Andrew G. Kuzmission, Hongren Wang
  • COCRYSTALS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF TREATMENT INVOLVING SAME
    Publication number: 20210198234
    Abstract: Provided are solid forms of a compound useful for treating cancer, pharmaceutical compositions thereof, and methods of treating cancer comprising administering the solid forms described herein to a patient in need thereof.
    Type: Application
    Filed: November 2, 2018
    Publication date: July 1, 2021
    Inventors: Benjamin S. LANE, Chong-Hui GU
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20210155603
    Abstract: Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein.
    Type: Application
    Filed: June 29, 2020
    Publication date: May 27, 2021
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20200397768
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: September 4, 2020
    Publication date: December 24, 2020
    Inventor: Chong-Hui Gu
  • Pharmaceutical compositions of therapeutically active compounds
    Patent number: 10799490
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: October 13, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Chong-Hui Gu
  • Therapeutically active compounds and their methods of use
    Patent number: 10730854
    Abstract: Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: August 4, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20190336487
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Application
    Filed: July 2, 2019
    Publication date: November 7, 2019
    Inventor: Chong-Hui Gu
  • Pharmaceutical compositions of therapeutically active compounds
    Patent number: 10449184
    Abstract: Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: October 22, 2019
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Chong-Hui Gu
  • PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF
    Publication number: 20190274959
    Abstract: The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
    Type: Application
    Filed: March 12, 2019
    Publication date: September 12, 2019
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni DOKOU, Shahla JAMZAD, John P. CAESAR, JR., Majed FAWAZ, Laura DAS, Chong-Hui GU, Patricia Nell HURTER, Meghna Jai ISRANI, Meghan M. JOHNSTON, Dragutin KNEZIC, Andrew G. KUZMISSION, HongRen WANG