Patents by Inventor Christer Betsholtz

Christer Betsholtz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glomerular expression profiling
    Publication number: 20060216722
    Abstract: The present invention provides compositions comprising various glomerular probe sets and methods for their use.
    Type: Application
    Filed: March 25, 2005
    Publication date: September 28, 2006
    Inventors: Christer Betsholtz, Karl Tryggvason, Minoru Takemoto, Liqun He, Jaakko Patrakkas
  • Isolation of target cells, capillaries and microorgans
    Publication number: 20060165662
    Abstract: An isolation method for target cells, capillaries and microorgans comprises perfusion of an organism with a solution containing magnetic beads, removal of a selected tissue or region of the organism, digestion of the portion removed and isolation of the target cells, capillaries or microorgans using a magnet. Filtration may be used to facilitate the method.
    Type: Application
    Filed: April 30, 2003
    Publication date: July 27, 2006
    Inventors: Minoru Takemoto, Christer Betsholtz
  • Recombinant PDGF A-chain homodimers and methods of use
    Patent number: 6939849
    Abstract: DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: September 6, 2005
    Assignee: Chiron Corporation
    Inventors: Carl-Henrik Heldin, Christer Betsholtz, Bengt Westermark, Timothy J. Knott, James Scott, Graeme I. Bell
  • Platelet-derived growth factor C, DNA coding therefor, and uses thereof
    Publication number: 20020164687
    Abstract: PDGF-C, a new member of the PDGF/VEGF family of growth factors, is described, as well as the nucleotide sequence encoding it, methods for producing it, antibodies and other antagonists to it, transfected and transformed host cells expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: May 10, 2001
    Publication date: November 7, 2002
    Inventors: Ulf Eriksson, Karin Aase, Xuri Li, Annica Ponten, Marko Uutela, Kari Alitalo, Arne Oestman, Carl-Henrik Heldin, Christer Betsholtz
  • Transgenic animal with recombinant vascular endothelial growth factor B (VEGF-B DNA) and uses thereof
    Patent number: 6262337
    Abstract: Transgenic animals containing recombinant DNA with modified nucleotide sequence from the vascular endothelial growth factor B (VEGF-B) gene, cells and methods for producing such animals, and methods of using them to assay substances for VEGF-B-like activity.
    Type: Grant
    Filed: February 18, 1998
    Date of Patent: July 17, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Gabriel von Euler, Karin Aase, Christer Betsholtz, Ulf Eriksson, Milos Pekny, Samuel Gebre-Medhin, Xuri Li
  • Recombinant DNA encoding PDGF A-chain polypeptides
    Patent number: 5605816
    Abstract: DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: February 25, 1997
    Assignee: Chiron Corporation
    Inventors: Carl-Henrik Heldin, Christer Betsholtz, Bengt Westermark, Timothy J. Knott, James Scott, Graeme I. Bell
  • Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors
    Patent number: 5219759
    Abstract: DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.
    Type: Grant
    Filed: August 27, 1990
    Date of Patent: June 15, 1993
    Assignee: Chiron Corporation
    Inventors: Carl-Henrik Heldin, Christer Betsholtz, Bengt Westermark, Timothy J. Knott, James Scott, Graeme I. Bell