Patents by Inventor Christian Bruns

Christian Bruns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090069225
    Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.
    Type: Application
    Filed: November 5, 2008
    Publication date: March 12, 2009
    Applicant: NOVARTIS AG
    Inventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
  • Patent number: 7473761
    Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: January 6, 2009
    Assignee: Novartis AG
    Inventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
  • Publication number: 20080284795
    Abstract: In a method and a device for controlling the display on a display area of a display device in a transportation device, data are generated for the display of a background region and data for the display in a subregion of the display area. The display in the subregion covers the display of the background region, and the display content in the subregion displays at least a portion of the display content of the background region covered by the subregion in a different manner than in the background region.
    Type: Application
    Filed: December 6, 2007
    Publication date: November 20, 2008
    Inventors: Andreas EBERT, Jens Fliegner, Christian Bruns, Martin Bonneberg
  • Publication number: 20080249111
    Abstract: Disclosed are compounds of formula I: wherein R1, R2, R3 and X are as defined herein, in free or salt form, which are useful as CCR5 inhibitors, e.g. in the prevention or treatment of disorders mediated by interactions between chemokine receptors and their ligands.
    Type: Application
    Filed: May 2, 2008
    Publication date: October 9, 2008
    Inventors: Rainer ALBERT, Nigel Graham Cooke, Gebhard Thoma, Christian Bruns, Francois Nuninger, Markus Streiff, Hans-Gunter Zerwes
  • Patent number: 7399771
    Abstract: Disclosed are compounds of formula I: wherein R1, R2, R3 and X are as defined herein, in free or salt form, which are useful as CCR5 inhibitors, e.g. in the prevention or treatment of disorders mediated by interactions between chemokine receptors and their ligands.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: July 15, 2008
    Assignee: Novartis AG
    Inventors: Rainer Albert, Nigel Graham Cooke, Gebhard Thoma, Christian Bruns, François Nuninger, Markus Streiff, Hans-Günter Zerwes
  • Publication number: 20060052289
    Abstract: Somatostatin analogues, e.g. comprising an amino acid sequence of formula -(D/L)Trp-Lys-X1-X2- wherein each of X1, and X2 is an amino acid residue as disclosed in the specification, have interesting properties in the treatment of sleep apnea.
    Type: Application
    Filed: December 30, 2003
    Publication date: March 9, 2006
    Inventors: Christian Bruns, Peter Marbach
  • Publication number: 20060004047
    Abstract: Disclosed are compounds of formula I: wherein R1, R2, R3 and X are as defined herein, in free or salt form, which are useful as CCR5 inhibitors, e.g. in the prevention or treatment of disorders mediated by interactions between chemokine receptors and their ligands.
    Type: Application
    Filed: October 6, 2003
    Publication date: January 5, 2006
    Inventors: Rainer Albert, Nigel Cooke, Gebhard Thoma, Christian Bruns, Francois Nuninger, Markus Streiff, Hans-Gunter Zerwes
  • Publication number: 20050014686
    Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.
    Type: Application
    Filed: July 30, 2001
    Publication date: January 20, 2005
    Inventors: Rainer Albert, Wlifried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meissenbach, Gisbert Weckbecker, Bernhard Wietfeld
  • Publication number: 20040167134
    Abstract: A method of treating a warm-blooded animal, especially a human, having a proliferative disease or acute or chronic transplant rejection comprising administering to the animal a combination which comprises (a) N-{5-[4-(4-methyl-piper-azino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and (b) a chemotherapeutic agent selected from antineoplastic agents, especially as defined herein, and agents effective in treating acute or chronic transplant rejection; a combination comprising (a) and (b) as defined above and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the delay of progression or treatment of a proliferative disease, especially a solid tumor disease.
    Type: Application
    Filed: April 7, 2004
    Publication date: August 26, 2004
    Inventors: Christian Bruns, Elisabeth Buchdunger, Terence O'Reilly, Sandra Leta Silberman, Markus Wartmann, Gisbert Weckbecker
  • Publication number: 20040142920
    Abstract: Piperidine derivatives of formula (I) as disclosed in the specification have interesting pharmaceutical properties e.g. as CCR5 inhibitors.
    Type: Application
    Filed: September 22, 2003
    Publication date: July 22, 2004
    Inventors: Rainer Albert, Christian Bruns, Francois Nuninger, Markus Streiff, Gebhard Thoma, Hans-Gunter Zerwes
  • Patent number: 6277356
    Abstract: Compounds of formula I wherein M is a cation equivalent and A is Phe or Tyr, in free form or in salt form are useful as radio pharmaceuticals when complexed with a radionuclide.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: August 21, 2001
    Assignee: Novartis AG
    Inventors: Rainer Albert, Christian Bruns, Peter Smith-Jones, Barbara Stolz, Gisbert Weckbecker
  • Patent number: 6225284
    Abstract: Somatostain analogues comprising the amino acid sequence of the formula (I): -(D/L)Trp-Lys-X1-X2, wherein X1 is a substituted Thr, Ser, Tyr, Glu or Cys residue and X2 is an &agr;-amino acid having an aromatic residue on the C&agr; side chain, or an amino acid unit selected from Dab, Dpr, Dpm, His (Bzl)HyPro, thienyl-Ala, cyclohexyl-Ala and t.-butyl-Ala, the residue Lys of said sequence corresponding to the residue Lys9 of the native somatostatin-14, in free form, in salt form or complexed with a detectable element have interesting pharmacological properties.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: May 1, 2001
    Assignee: Novartis AG
    Inventors: Rainer Albert, Wilfried Bauer, Christian Bruns, Nagarajan Chandramouli, Ian Lewis, Gisbert Weckbecker
  • Patent number: 6183721
    Abstract: Compounds of formula I wherein M is a cation equivalent and A is Phe or Tyr, in free form or in salt form are useful as radiopharmaceuticals when complexed with a radionuclide.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: February 6, 2001
    Assignee: Novartis AG
    Inventors: Rainer Albert, Christian Bruns, Peter Smith-Jones, Barbara Stolz, Gisbert Weckbecker
  • Patent number: 5841487
    Abstract: In a circuit arrangement for direct current control of a picture display tube having a non-linear voltage/current characteristic by a precorrected picture signal, the picture signal is applied to a non-linear compensation circuit (3) which cancels the precorrection of the picture signal and controls a controlled current source (8) at the output end, whose output is coupled to the cathode (10) of the picture display tube (1), and a differentiator (13) is provided which differentiates the picture signal and controls a voltage-controlled compensation current source (12) which is coupled to the cathode (10) of the picture display tube (1) for a picture signal-dependent reversal of the charge of the parasitic input capacitance (11) of this picture display tube.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: November 24, 1998
    Assignee: U.S. Philips Corporation
    Inventors: Matthias Peters, Christian Brun
  • Patent number: 5260280
    Abstract: Sialic acid binding proteins, sialic acid-binding peptides and sialic acid containing oligo-saccharides are active ingredients of a novel bacterial enterotoxin neutralizer and interfere with the binding of enterotoxins, including cholera toxin, to receptors so as to exert an effect of neutralizing the toxicity, thus being utilized as an effective neutralizer and are safe and available cheaply and abundantly from by-products produced during the processing of cow's milk which renders the enterotoxin neutralizer economically advantageous for commercial use.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: November 9, 1993
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Hiroko Isoda, Yoshihiro Kawasaki, Morimasa Tanimoto, Shunichi Dosako, Tadashi Idota