Patents by Inventor Christian Maloizel

Christian Maloizel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8258168
    Abstract: Compounds corresponding to the formula (I) as defined in the disclosure, as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the invention, and methods of treatment using them.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: September 4, 2012
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Christian Maloizel, Mireille Sevrin
  • Publication number: 20120108584
    Abstract: Compounds corresponding to the formula (I) as defined in the disclosure, as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the invention, and methods of treatment using them.
    Type: Application
    Filed: January 11, 2012
    Publication date: May 3, 2012
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick Evanno, Christian Maloizel, Mireille Sevrin
  • Patent number: 8114899
    Abstract: Compounds corresponding to the formula (I) as defined in the disclosure, as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the invention, and methods of treatment using them.
    Type: Grant
    Filed: January 27, 2009
    Date of Patent: February 14, 2012
    Assignee: Sanofi-Aventis
    Inventors: Laurent DuBois, Yannick Evanno, Christian Maloizel, Mireille Sevrin
  • Patent number: 7868024
    Abstract: The invention relates to compounds of formula (I): Wherein X1, X2, X3, X4, Y and W are as described herein. The invention also relates to a preparation method and to a therapeutic application.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: January 11, 2011
    Assignee: Sanofi-Aventis
    Inventors: Laurent Dubois, Yannick Evanno, André Malanda, Christian Maloizel
  • Publication number: 20090306143
    Abstract: The invention relates to compounds of formula (I): Wherein X1, X2, X3, X4, Y and W are as described herein. The invention also relates to a preparation method and to a therapeutic application.
    Type: Application
    Filed: July 17, 2009
    Publication date: December 10, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, André MALANDA, Christian MALOIZEL
  • Publication number: 20090143380
    Abstract: Compounds corresponding to the formula (I) as defined in the disclosure, as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the invention, and methods of treatment using them.
    Type: Application
    Filed: January 27, 2009
    Publication date: June 4, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick Evanno, Christian Maloizel, Mireille Sevrin
  • Patent number: 7501449
    Abstract: Compounds corresponding to the formula (I) as defined in the disclosure as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the invention, and methods of treatment using them.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: March 10, 2009
    Assignee: Sanofi-Aventis
    Inventors: Laurent DuBois, Yannick Evanno, Christian Maloizel, Mireille Sevrin
  • Publication number: 20070105932
    Abstract: Compounds corresponding to the formula (I) as defined in the disclosure as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the invention, and methods of treatment using them.
    Type: Application
    Filed: October 13, 2006
    Publication date: May 10, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Christian MALOIZEL, Mireille SEVRIN
  • Patent number: 6075021
    Abstract: Compounds of general formula (I) ##STR1## in which the variables are as defined in the specification, their preparation and their application in therapeutics.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: June 13, 2000
    Assignee: Synthelabo
    Inventors: Yannick Evanno, Mireille Sevrin, Christian Maloizel, Odette Legalloudec, Pascal George
  • Patent number: 5380742
    Abstract: Pyrrole derivatives of formula: ##STR1## in which R.sub.1 represents a hydrogen or halogen atom, a linear or branched C.sub.1-6 alkyl group, a C.sub.3-6 alkenyl group, a C.sub.1-4 alkoxymethyl group, benzyl, a phenyl group optionally substituted by one or more halogen atoms or alkyl radicals, a CO.sub.2 R group in which R represents a linear or branched C.sub.1-4 alkyl radical, phenyl or benzyl, or a CONR'R" group in which R' and R" each represent, independently of one another, a hydrogen atom or a linear or branched C.sub.1-4 alkyl radical,R.sub.2 represents a hydrogen or halogen atom or a linear or branched C.sub.1-4 alkyl group,and R.sub.3 represents a 4,5-dihydro-1H-imidazol-2-yl or 1H-imidazol-4-yl group, and their addition salts with pharmaceutically acceptable acids are useful in therapeutics as .alpha..sub.2 -antagonists, and .alpha..sub.1 -agonists.
    Type: Grant
    Filed: November 24, 1993
    Date of Patent: January 10, 1995
    Assignee: Synthelabo
    Inventors: Mireille Sevrin, Jacques Menin, Christian Maloizel, Juan A. Diaz Martin, Ulpiano Martin Escudero Perez, Manuel Bedoya Zurita, Gregorio Del Sol Moreno, Maria D. Jimenez Bargueno, Magali Romanach Ferrer
  • Patent number: 5254560
    Abstract: A compound which is a carboxamide derivative of general formula (I) ##STR1## in which R represents a hydrogen atom, a methyl group or a phenoxyalkyl group of general formula ##STR2## in which X represents one or more substituents independently chosen from hydrogen, fluorine, chlorine, methyl, 1-methylethyl and methoxy andn is 2 or 3,m is 0 or 1 andp is 1 or 2 such that m+p=2q is 0 or 1, andR.sub.1 represents a hydrogen atom or a methyl group,or a pharmaceutically acceptable acid addition salt thereof. Process for their preparation and their therapeutic use.
    Type: Grant
    Filed: June 26, 1992
    Date of Patent: October 19, 1993
    Assignee: Synthelabo
    Inventors: Pascal George, Christian Maloizel, Benoit Marabout, Jean-Pierre Merly
  • Patent number: 5246939
    Abstract: A compound which is a 2-aminopyrimidine carboxamide derivative represented by formula (I) ##STR1## in which X represents hydrogen, fluorine, chlorine, methyl, 1-methylethyl or methoxy, with the proviso that more than one substituent X may be present in which case each X may be the same or different,n represents 2 or 3,m represents 1, in which case p represents 1, or elsem represents 0, in which case p represents 2,q represents 0 or 1, andR.sub.1 represents a hydrogen atom;or a pharmaceutically acceptable acid addition salt thereof.A compound of formula (I) has .alpha..sub.1 -adrenergic receptor antagonist activity and is useful as a therapeutic substance.
    Type: Grant
    Filed: June 26, 1992
    Date of Patent: September 21, 1993
    Assignee: Synthelabo
    Inventors: Pascal George, Christian Maloizel, Benoit Marabout, Jean-Pierre Merly
  • Patent number: 5210086
    Abstract: A compound which is a 2-aminopyrimidine-4-carboxamide derivative, of the general formula (I) ##STR1## in which m is 0 or 1,p is 0 or 1,q is 1 or 2,n is 2 or 3,R.sub.1 represents a hydrogen atom or a methyl group, and X represents at least one substituent selected from hydrogen, fluorine, chlorine, methoxy, methyl, isopropyl,or a pharmaceutically acceptable addition salt thereof, its preparation and use in therapy.
    Type: Grant
    Filed: October 1, 1991
    Date of Patent: May 11, 1993
    Assignee: Synthelabo
    Inventors: Pascal George, Christian Maloizel, Benoit Marabout
  • Patent number: 4925850
    Abstract: A compound of formula (I): ##STR1## in which: X is hydrogen or a methyl or methoxy group;Y is a halogen or a methyl or methoxy group; andR is a group of formula --Z--R' in which:Z is a --CH.sub.2 -- group, andR' is a phenyl group unsubstituted or substituted by one, two or three substituents selected from halogen atoms and trifluoromethyl, linear or branched (C.sub.1 -C.sub.3) alkyl and linear or branched (C.sub.1 -C.sub.3) alkoxy groups;or a pharmacologically acceptable acid addition salt thereof.
    Type: Grant
    Filed: February 6, 1989
    Date of Patent: May 15, 1990
    Assignee: Synthelabo
    Inventors: Pascal George, Mireille Sevrin, Christian Maloizel, Arlette Tixidre, Jacques Froissant
  • Patent number: 4885302
    Abstract: A compound of formula (I) ##STR1## in which R is (a) a hydrogen atom;(b) a linear or branched (C.sub.1 -C.sub.6) alkyl group; an allyl group; a cycloalkylmethyl group in which the cycloalkyl moiety has from 3 to 6 carbon atoms; a phenylmethyl group unsubstituted or substituted with one to three substituents chosen from halogen atoms and trifluoromethyl, nitro, amino, dimethylamino, cyano, aminocarbonyl, linear or branched (C.sub.1 -C.sub.3) alkyl, linear or branched (C.sub.1 -C.sub.3) alkoxy and linear or branched (C.sub.1 -C.sub.3) alkylthio groups; a 2-phenylethyl group; a 3-phenylpropyl group; a 3-phenyl-2-propenyl group; a phenylcarbonylmethyl group; a naphthylmethyl group; a pyridylmethyl group; a furylmethyl group; or a thienylmethyl group; or(c) a linear or branched (C.sub.2 -C.sub.
    Type: Grant
    Filed: August 5, 1988
    Date of Patent: December 5, 1989
    Inventors: Pascal George, Mireille Sevrin, Christian Maloizel
  • Patent number: 4659731
    Abstract: Derivatives of formula (I) ##STR1## in which X denotes a hydrogen or halogen atom, an alkoxy radical, an alkyl radical or an allyloxy radical, and R denotes a linear or branched alkyl radical, a cycloalkylalkyl radical, an alkenyl radical, an arylalkyl radical which can bear one or more substituents chosen from halogen atoms and methyl, methoxy and methylenedioxy radicals, or alternatively an optionally substituted phenyl radical, as well as the addition salts thereof with pharmaceutically acceptable acids produce an .alpha..sub.2 -receptor antagonist effect.
    Type: Grant
    Filed: February 5, 1986
    Date of Patent: April 21, 1987
    Assignee: Synthelabo
    Inventors: Denis Bigg, Jacques Menin, Christian Maloizel, Jean Merly