Patents by Inventor Christian Schopke

Christian Schopke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20240084316
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 14, 2024
    Applicants: CIBUS US LLC, Cibus Europe B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20230407322
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: January 2, 2023
    Publication date: December 21, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20230313211
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Application
    Filed: August 22, 2022
    Publication date: October 5, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel Joy SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 11761011
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: September 19, 2023
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20230141977
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Application
    Filed: September 5, 2022
    Publication date: May 11, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel Joy SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 11542515
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: January 3, 2023
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES
    Publication number: 20220298525
    Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the disclosure relates to plants that are herbicide resistant.
    Type: Application
    Filed: September 7, 2021
    Publication date: September 22, 2022
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Gregory F.W. Gocal, Peter R. Beetham, Aura Estela Gonzalez Schopke, Sarah Dumm, James Pearce, Christian Schopke, Keith A. Walker
  • Targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 11434494
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 6, 2022
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Joy Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 11421240
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: August 23, 2022
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Joy Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Mutated protoporphyrinogen IX oxidase (PPX) genes
    Patent number: 11111500
    Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the disclosure relates to plants that are herbicide resistant.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: September 7, 2021
    Assignees: CIBUS US LLC, CIBUS Europe B.V.
    Inventors: Gregory F. W. Gocal, Peter R. Beetham, Aura Estela Gonzalez Schopke, Sarah Dumm, James Pearce, Christian Schopke, Keith A. Walker
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20210261974
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: March 22, 2021
    Publication date: August 26, 2021
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 10954522
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: March 23, 2021
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • MUTATED ACETOHYDROXYACID SYNTHASE GENES IN BRASSICA
    Publication number: 20200123563
    Abstract: Provided are mutated acetohydroxyacid synthase (AHAS) nucleic acids and the proteins encoded by the mutated nucleic acids. Also provided are canola plants, cells, and seeds comprising the mutated genes.
    Type: Application
    Filed: December 27, 2019
    Publication date: April 23, 2020
    Applicant: Cibus US LLC
    Inventors: Christian Schopke, Gregory F. W. Gocal, Keith A. Walker, Peter R. Beetham
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20190264219
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Application
    Filed: May 13, 2019
    Publication date: August 29, 2019
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel Joy SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20190249182
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: September 16, 2016
    Publication date: August 15, 2019
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 10287594
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 14, 2019
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Joy Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES
    Publication number: 20180327773
    Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the disclosure relates to plants that are herbicide resistant.
    Type: Application
    Filed: July 23, 2018
    Publication date: November 15, 2018
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Gregory F.W. Gocal, Peter R. Beetham, Aura Estela Gonzalez Schopke, Sarah Dumm, James Pearce, Christian Schopke, Keith A. Walker
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20180320190
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: April 30, 2018
    Publication date: November 8, 2018
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for targeted gene modification
    Patent number: 9957515
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: May 1, 2018
    Assignees: CIBUS US LLC, CIBUS EUROPE, B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20170081674
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: March 14, 2015
    Publication date: March 23, 2017
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK