Patents by Inventor Christian Sirrenberg

Christian Sirrenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diacylhydrazine derivatives
    Publication number: 20070093529
    Abstract: The present invention relates to diacylhydrazine derivatives of formula I, the use of the compounds of formula I as inhibitors of raf-kinase, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.
    Type: Application
    Filed: November 11, 2004
    Publication date: April 26, 2007
    Inventors: Dirk Finsinger, Hans-Peter Buchstaller, Lars Burgdorf, Christiane Amendt, Matthias Grell, Christian Sirrenberg, Frank Zenke
  • Benzimidazole carboxamides as raf kinase inhibitors
    Publication number: 20070093532
    Abstract: The present invention relates to benzimidazole carboxamides of formula (I), the use of the compounds of formula (I) as inhibitors of as inhibitors of one or more kinases, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient. Accordingly, the compound of Formula (I) or a pharmaceutically acceptable salt thereof is administered for the treatment of diseases mediated by one or more kinase phathways, preferably by the raf kinase pathway, especially cancers.
    Type: Application
    Filed: June 11, 2004
    Publication date: April 26, 2007
    Applicant: MERCK PATENT GmbH
    Inventors: Hans-Peter Buchstaller, Matthias Wiesner, Frank Zenke, Christiane Amendt, Matthias Grell, Christian Sirrenberg
  • Methylene urea derivatives
    Publication number: 20060199844
    Abstract: The present invention relates to methylene urea derivatives of formula (I), the use of the compounds of formula (I) as inhibitors of raf-kinase, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.
    Type: Application
    Filed: October 8, 2003
    Publication date: September 7, 2006
    Applicant: Merck Patent GmbH
    Inventors: Hans-Peter Buchstaller, Matthias Wiesner, Oliver Schadt, Christiane Amendt, Frank Zenke, Christian Sirrenberg, Matthias Grell, Dirk Finsinger
  • Oxamide derivatives useful as raf-kinase inhibitors
    Publication number: 20060189665
    Abstract: The present invention relates to oxamide derivatives of Formula (I), the use of the compounds of Formula (I) as inhibitors of raf-kinase, the use of the compounds of Formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.
    Type: Application
    Filed: March 9, 2004
    Publication date: August 24, 2006
    Applicant: MERCK PATENT GMBH
    Inventors: Hans-Peter Buchstaller, Matthias Wiesner, Frank Zenke, Christiane Amendt, Matthias Grell, Christian Sirrenberg
  • Glycinamide derivatives as raf-kinase inhibitors
    Publication number: 20060167261
    Abstract: The present invention relates to glycinamide derivatives of formula (I), the use of the compounds of formula (I) as inhibitors of raf-kinase, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.
    Type: Application
    Filed: July 31, 2003
    Publication date: July 27, 2006
    Applicant: Merk Patent GmbH
    Inventors: Hans-Peter Buchstaller, Matthias Wiesner, Oliver Schadt, Christiane Amendt, Frank Zenke, Christian Sirrenberg, Matthias Grell
  • Heparanase-2 a member of the heparanase protein family
    Patent number: 6872558
    Abstract: Heparanase-2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing heparanese-2 polypeptides and polynucleotides and diagnostic assays.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: March 29, 2005
    Assignee: Merck Patent GmbH
    Inventors: Klaus Dücker, Christian Sirrenberg
  • Chromenone derivatives
    Publication number: 20040220182
    Abstract: Novel compounds of the formula I 1
    Type: Application
    Filed: April 28, 2004
    Publication date: November 4, 2004
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Wilfried Rautenberg, Christian Sirrenberg
  • 2-Benzoylchromone derivatives
    Publication number: 20040176440
    Abstract: Novel compounds of the formula I 1
    Type: Application
    Filed: December 2, 2003
    Publication date: September 9, 2004
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • 2-Oxadiazolechromone derivatives
    Publication number: 20040138464
    Abstract: Novel compounds of the formula I 1
    Type: Application
    Filed: December 2, 2003
    Publication date: July 15, 2004
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Ras guanine-nucleotide-exchange factor 1 (nrg1)
    Publication number: 20030108932
    Abstract: New Ras Guanine-nucleotide-exchange factor 1 (NRG1)polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing New Ras Guanine-nucleotide-exchange factor 1 (NRG1)polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: November 4, 2002
    Publication date: June 12, 2003
    Inventor: Christian Sirrenberg
  • Gtpase-activating protein 1
    Publication number: 20030096282
    Abstract: New GTPase-Activating Protein 1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing New GTPase-Activating Protein 1 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: October 30, 2002
    Publication date: May 22, 2003
    Inventors: Christian Sirrenberg, Bjorn Hock, Jorg Dietrich Hoheisel, Marcus Frohme