Patents by Inventor Christof Fattinger

Christof Fattinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100086440
    Abstract: In some embodiments of the present disclosure, a robotic storage system for storing microplates carrying a plurality of sample tubes is provided and may comprise a freezer room having a plurality of freezing units and a first robot being capable of removing a microplate from and moving a microplate into a freezing unit. The first robot may be further capable of transferring the microplate to a processing station, where the microplates are stored in the freezing units such that a plurality of microplates are arranged one above the other in a microplate recipient. The robotic storage system may also include at least one processing room and means for thermally separating the processing room from the freezer room. Each processing room may include a processing station having at least one tube transfer module as well as a second robot for moving the microplates between the microplate recipients and the at least one tube transfer module.
    Type: Application
    Filed: September 30, 2009
    Publication date: April 8, 2010
    Applicant: F. Hoffmann-La Roche AG
    Inventors: Christof Fattinger, Remo Anton Hochstrasser, Dieter Voegelin, Thomas Zumstein
  • Publication number: 20100031685
    Abstract: Embodiments of the present invention include a convection barrier for a freezer which may comprise a plurality of individual flaps arranged one above the other in a manner such as to be capable of forming a closed curtain of individual flaps, with each individual flap extending over a predetermined width corresponding at least to the width of the interior of the freezer and being pivotable between a closed position and an open position so as to allow access to the interior of the freezer when the flap is in the open position. Embodiments may also include actuation means attached to the individual flaps for allowing an actuator to engage the actuation means of an individual flap so as to pivot the said flap between the closed position and the open position.
    Type: Application
    Filed: July 31, 2009
    Publication date: February 11, 2010
    Applicant: F. Hoffmann-La Roche AG
    Inventors: Thomas Zumstein, Christof Fattinger, Dieter Voegelin
  • Publication number: 20100005826
    Abstract: A convection barrier for a freezer is disclosed. The convection barrier may include a foil having at least one opening therein, storage and transport means for storing and moving the foil so as to transport the at least one opening to a desired position allowing access through the at least one opening to the interior of the freezer at the desired position and tensioning means for continuously keeping the foil in a tensioned state.
    Type: Application
    Filed: July 8, 2009
    Publication date: January 14, 2010
    Applicant: F. HOFFMANN-LA ROCHE AG
    Inventors: Thomas Zumstein, Christof Fattinger, Remo Anton Hochstrasser
  • Patent number: 7597848
    Abstract: A transport system for transporting and handling microtiter plates, for use in high throughput screening, diagnosis and/or combinatorial chemistry, comprising modules with devices for preparing specimens and/or introducing specimens, and/or for optical readout and/or for plate storage and/or devices for further processing steps or readout steps. The system includes an inter-modular transport system for transporting the microtiter plates between the different devices and at least one central transport system for asynchronous plate transfer between individual modules via input and output buffers.
    Type: Grant
    Filed: July 30, 1999
    Date of Patent: October 6, 2009
    Assignees: Carl Zeiss Jena GmbH, F. Hoffmann-LaRoche AG
    Inventors: Richard Ameling, Thilo Enderle, Christof Fattinger, Martin Gluch, Hansjoerg Tschirky
  • Publication number: 20050136546
    Abstract: A microtiter plate for processing samples, having a liquid component or a liquid and a solid component or a liquid and a gel component, comprising: a single piece body which has an array of cavities, each cavity having an open upper end, a closed bottom end, and a bottom inner surface and comprises a first chamber for receiving a predetermined volume of a sample to be processed, a second chamber and a passage which fluidically connects the first and second chambers with each other, and a region in the lower part of passage adjacent to the bottom end of the cavity, the region so configured and dimensioned that it allows passage of liquid from one of said chambers to the other only when a centrifugal force is applied to the microtiter plate, but does not allow passage of any solid or gel component the size of which is larger than the width of the region.
    Type: Application
    Filed: December 13, 2004
    Publication date: June 23, 2005
    Inventors: Peter Berndt, Gregor Dernick, Christof Fattinger, Remo Hochstrasser, Dieter Voegelin
  • Patent number: 6827907
    Abstract: A compound handling system handles a multiplicity of chemical or biological compounds or samples, and is especially adapted for high throughput screening of compounds that are stored and handled in aliquotted form. Aliquots are contained in individual containers and the containers are arranged in racks having holding spaces open at opposite ends. Insertion and removal of the containers is effected in either direction of movement, and each container may be sealed with foil to protect its integrity.
    Type: Grant
    Filed: December 20, 2000
    Date of Patent: December 7, 2004
    Assignee: Hoffmann-LA Roche Inc.
    Inventors: Christof Fattinger, Hansjörg Tschirky
  • Publication number: 20030209091
    Abstract: Method and apparatus for transporting a plurality of test tubes (11) in a measuring system, the test tubes being carried by a test tube carrier (21) which comprises a plurality of compartments (22), each of which is adapted for receiving and holding a test tube.
    Type: Application
    Filed: May 9, 2003
    Publication date: November 13, 2003
    Inventors: Christof Fattinger, Remo Anton Hochstrasser, Hansjorg Tschirky
  • Patent number: 6473239
    Abstract: The invention relates to an imaging system for optical automatic analysers, especially fluorescence readers. On the sample side, the imaging system contains a cylindrical lens array and a prism array, which is arranged upstream of the cylindrical lens array. The prismatic effect of the prisms of the prism array lies in the direction of the cylinder axes of the cylindrical lenses. Together with a telescopic imaging system, the inventive imaging system creates a number of parallel cylindrical focussing volumes between the cylindrical lens array and a detector array, these focussing volumes being slanted towards the optical axis of the telescopic system in relation to the vertical. The arrangement enables the detection of fluorescence with a large aperture in one direction, and at the same time enables depth selective analysis of the fluorescence signal, especially the discrimination of the fluorescent radiation originating from the solution above.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: October 29, 2002
    Assignee: Carl-Zeiss-Stiftung
    Inventors: Martin Völcker, Christof Fattinger
  • Patent number: 6415995
    Abstract: A microdispensing system is useful for the open-jet dispensing of liquids. A valve having a valve chamber is bounded by an impermeable elastic membrane and is filled with the liquid for dispensing. One or more liquid supply lines lead to the valve chamber. An outlet closed from the exterior by the membrane in the position of rest leads from the chamber to a dispensing nozzle. An actuator chamber is disposed on the other side of the membrane. In the actuator chamber, an electromechanical drive is connected to the membrane for the purpose of briefly lifting the membrane from the outlet. The actuator chamber is closed in such manner that it can be subjected to a pressure differing from atmospheric pressure.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: July 9, 2002
    Assignee: Cybio AG
    Inventors: Thilo Enderle, Christof Fattinger, Gerhard Flury, Hans-Peter Hirt, Rene Rietmann, Hansjörg Tschirky
  • Publication number: 20020030894
    Abstract: The invention relates to an imaging system for optical automatic analysers, especially fluorescence readers. On the sample side, the imaging system contains a cylindrical lens array and a prism array, which is arranged upstream of the cylindrical lens array. The prismatic effect of the prisms of the prism array lies in the direction of the cylinder axes of the cylindrical lenses. Together with a telescopic imaging system, the inventive imaging system creates a number of parallel cylindrical focussing volumes between the cylindrical lens array and a detector array, these focussing volumes being slanted towards the optical axis of the telescopic system in relation to the vertical. The arrangement enables the detection of fluorescence with a large aperture in one direction, and at the same time enables depth selective analysis of the fluorescence signal, especially the discrimination of the fluorescent radiation originating from the solution above.
    Type: Application
    Filed: April 12, 2001
    Publication date: March 14, 2002
    Inventors: Martin Volcker, Christof Fattinger
  • Publication number: 20010002986
    Abstract: A compound handling system handles a multiplicity of chemical or biological compounds or samples, and is especially adapted for high throughput screening of compounds that are stored and handled in aliquotted form. Aliquots are contained in individual containers and the containers are arranged in racks having holding spaces open at opposite ends. Insertion and removal of the containers is effected in either direction of movement, and each container may be sealed with foil to protect its integrity.
    Type: Application
    Filed: December 20, 2000
    Publication date: June 7, 2001
    Inventors: Christof Fattinger, Hansjorg Tschirky
  • Patent number: 5712705
    Abstract: Arrangement for analysis of substances at or near the surface of an optical sensor with at least one wave-guiding film and at least one multidiffraction grating coupler for in-coupling and out-coupling of light beams, in which at least two light beams enclosing an angle .alpha. relative to one another are coupled in and by which at least two light beams enclosing an angle .phi. relative to one another are coupled out, and with a detection system for detecting the out-coupled light beams, wherein in-coupling and out-coupling are effected on one and the same side of the sensor and the in-couple beams and out-couple beams lie in different quadrants of the plane of incident light, and the angle .alpha. between the in-couple beams is greater than the angle .phi. between the out-couple beams. The arrangement has multiple uses for determining physical or chemical measured quantities based on the interaction of the guided light waves with the medium at or near the sensor surface.
    Type: Grant
    Filed: July 7, 1995
    Date of Patent: January 27, 1998
    Assignees: Carl Zeiss Jena GmbH, F. Hoffman-La Roche, Schott Glaswerke
    Inventors: Christof Fattinger, Burkhard Danielzik, Dieter Graefe, Martin Heming, Frank-Thomas Lentes
  • Patent number: 5480687
    Abstract: An optical waveguide is disclosed with a substantially planar substrate and a waveguide layer applied to the substrate. The invention resides in that the substrate consists of a synthetic resin or of a material having a high organic proportion. This has the advantage that the high index of refraction of the inorganic waveguide layer is combined with the material properties of the synthetic resin substrate, such as, for example, breaking resistance, plastic and thermoplastic moldability, photochemical structuring ability, and others.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: January 2, 1996
    Assignees: Schott Glaswerke, Hoffmann-La Roche, A.G.
    Inventors: Martin Heming, Roland Hochhaus, Ralf Kersten, Dieter Krause, Jurgen Otto, Volker Paquet, Johannes Segner, Christof Fattinger
  • Patent number: 5479260
    Abstract: The optical process for analyzing substances is based on the measurement of the propagation properties of optical surface waves on sensor surfaces. In a wave guide layer structure in contact with a sample, guided light waves are decoupled with a grating coupler. The decoupling region of the grating coupler is imaged onto a position resolving detector so that the plane of the wave guide layer structure forms the object plane and the detection plane lies in the image plane of the optical imaging. The light distribution of the decoupled wave field in the image plane is measured with the detector and used to determine the analytical quantity to be measured. The device for carrying out the process consists of a suitable wave guide sensor with grating coupler, an imaging lens system and an optical detector (10).
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: December 26, 1995
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Christof Fattinger
  • Patent number: 5455178
    Abstract: A microoptical sensor and a corresponding method for detecting chemical substances in a sample. The sample is brought into contact with the waveguiding layer of a planar optical waveguide. Coherent light is coupled into the waveguiding layer, propagates therein as a guided wave, and the latter is decoupled from the waveguiding layer. Both, coupling and decoupling of the light wave guided in the planar waveguide is effected by means of a multi-diffractive grating situated in the plane of the layer, i.e. a grating structure comprising two or more fundamental frequency components for in-coupling and out-coupling, respectively. The multi-diffractive grating coupler results in a directional separation of decoupled light from reflected, transmitted and directly diffracted sub-beams, respectively.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: October 3, 1995
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Christof Fattinger
  • Patent number: 5369722
    Abstract: An optical waveguide is disclosed with a substantially planar substrate and a waveguide layer applied to the substrate. The invention resides in that the substrate consists of a synthetic resin or of a material having a high organic proportion. This has the advantage that the high index of refraction of the inorganic waveguide layer is combined with the material properties of the synthetic resin substrate, such as, for example, breaking resistance, plastic and thermoplastic moldability, photochemical structuring ability, and others.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: November 29, 1994
    Assignees: Schott Glaswerke, Hoffmann-LaRoche, A.G.
    Inventors: Martin Heming, Roland Hochhaus, Ralf Kersten, Dieter Krause, Jurgen Otto, Volker Paquet, Johannes Segner, Christof Fattinger
  • Patent number: D562463
    Type: Grant
    Filed: May 3, 2005
    Date of Patent: February 19, 2008
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Peter Berndt, Christof Fattinger, Remo Anton Hochstrasser, Tom Kissling