Patents by Inventor Christoph Huels

Christoph Huels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulatory T-Cells Containing Galectins for the Therapy and Diagnosis of Diseases
    Publication number: 20080118515
    Abstract: The invention relates to regulator T-cells containing galectins, in particular, the use thereof as markers and for the therapy and diagnosis of diseases, in particular, of allergies and autoimmune diseases, in particular rheumatoid arthritis, multiple sclerosis or Crohn's disease, chronic inflammation, asthma, immune deficiency diseases, AIDS, transplant rejection, cancer diseases and diabetes.
    Type: Application
    Filed: July 15, 2004
    Publication date: May 22, 2008
    Applicant: PROTAGEN AG
    Inventors: Petra Lutter, Petra Weingarten, Christoph Huels, Hemut E. Meyer, Edgar Schmitt, Helmut Jonuleit
  • 5-Membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists
    Publication number: 20040220148
    Abstract: Compounds of the formula I 1
    Type: Application
    Filed: October 24, 2003
    Publication date: November 4, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Hans Ulrich Stilz, Volkman Wehner, Jochen Knolle, Eckart Bartnik, Christoph Huels
  • Expression vector for the production of dead proteins
    Patent number: 6582691
    Abstract: The invention relates to an insect cell vector for the production of proteins from the DEAD protein family.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: June 24, 2003
    Assignee: Aventis Research & Technologies GmbH & Co.
    Inventors: Karl-Christian Gallert, Stefan Müllner, Christoph Hüls, Britta Böhnisch
  • Test system for detecting a splicing reaction and use thereof
    Patent number: 6579681
    Abstract: The present invention relates to a test system comprising (a) one or more identical or different immobilized nucleic acid(s) having at least one spliceable nucleic acid, (b) at least one gel-free detection system for detecting a splicing reaction, where appropriate (c) at least one composition comprising splicing components, and preferably (d) suitable detection probes, and, where appropriate, (e) further aids.
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: June 17, 2003
    Assignee: Aventis Research and Technologies GmbH & Co. KG
    Inventors: Christoph Hüls, Bettina Bauer, Claus Simandi, Reinhard Lührmann, Tilmann Achsel, Hans-Peter Vornlocher
  • Hydantoin derivatives as inhibitors of leucocyte adhesion and as VLA-4 antagonists
    Patent number: 6514952
    Abstract: Compounds of the formula I in which B, D, E, R, W, Y, Z, b, c, d, e, f, g and have the meanings indicated in the claims, are inhibitors of the adhesion and migration of leucocytes and/or antagonists of the adhesion receptor VLA-4 which belongs to the group of integrins. The invention relates to the use of compounds of the formula I, and of pharmaceutical preparations which contain such compounds, for the treatment and prophylaxis of diseases which are caused by an undesired extent of leucocyte adhesion and/or leucocyte migration or which are associated therewith or in which cell—cell or cell-matrix interactions play a part which are based on interactions of VLA-4 receptors with their ligands, for example of inflammatory processes, rheumatoid arthritis or allergic disorders, and it also relates to the use of compounds of the formula I for the production of pharmaceuticals for use in such diseases. It further relates to novel compounds of the formula I.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: February 4, 2003
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Ulrich Stilz, Volkmar Wehner, Christoph Huels, Dirk Seiffge
  • 3?-exonuclease, production and use thereof
    Patent number: 6451307
    Abstract: The present invention relates to a poly(A)-specific 3′-exonuclease activity which can be obtained by chromatographically purifying a crude extract of animal or human cells and to its use for deadenylating 3′-poly(A) tails of nucleic acids and as a pharmaceutical or diagnostic agent, or for identifying functional interactors.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: September 17, 2002
    Assignee: Aventis Research & Technologies GmbH & Co. KG
    Inventors: Thomas Neumann, Christoph Hüls, Karl-Christian Gallert, Anders Virtanen, Jonas Aström, Javier Martinez, Ann-Charlotte Thuresson, Yanguo Ren
  • Heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists
    Patent number: 5998447
    Abstract: Compounds of the formula I ##STR1## in which B, D, E, R, W, Y, Z, b, c, d, e, f, g and have the meanings indicated in the claims, are inhibitors of the adhesion and migration of leucocytes and/or antagonists of the adhesion receptor VLA-4 which belongs to the group of integrins. The invention relates to the use of compounds of the formula I, and of pharmaceutical preparations which contain such compounds, for the treatment and prophylaxis of diseases which are caused by an un desired extent of leucocyte adhesion and/or leucocyte migration or which are associated therewith or in which cell--cell or cell-matrix interactions play a part which are based on interactions of VLA-4 receptors with their ligands, for example of inflammatory processes, rheumatoid arthritis or allergic disorders, and it also relates to the use of compounds of the formula I for the production of pharmaceuticals for use in such diseases. It further relates to novel compounds of the formula I.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: December 7, 1999
    Assignee: Hoechst Aktiengesellschaft AG
    Inventors: Hans Ulrich Stilz, Volkmar Wehner, Christoph Huels, Dirk Seiffge