Patents by Inventor Christoph Klein

Christoph Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7410117
    Abstract: The invention relates to a device for deflecting sections of strip, in particular metal strip, in a coiling plant, from a beginning guide channel (1) to an end guide channel (2) and vice-versa, comprising a driver (3) with a pair of driver rollers (4, 4?) and control elements arranged downstream in strip conveyance direction, comprising a switch (5) that can be swiveled towards the beginning guide channel (1) or the end guide channel (2), and a guide table (6) which is swivelably supported under the switch (5) and positionable as a wiper against the lower driver roller (4?).
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: August 12, 2008
    Assignee: SMS Demag AG
    Inventors: Christoph Klein, Günter Kneppe, Karl Hoen
  • Publication number: 20070200281
    Abstract: The invention relates to a device for the production of hot-rolled steel strip comprising at least one continuous casting machine, at least one pair of scissors, at least one calibration oven, a de-scaler, optionally, a roughing train, a finishing train (multi-stand rolling mill or Steckel mill(s)), a roller path comprising a cooling area and at least one pickup reel for the thermal strip. A compact structure is achieved by virtue of the fact that the casting line and the rolling line are arranged parallel or approximately parallel to each other such that the direction of casting and direction of rolling are oriented essentially in an opposite direction to each other.
    Type: Application
    Filed: June 17, 2004
    Publication date: August 30, 2007
    Inventors: Christoph Klein, Jurgen Muller, Karl Rittner, Dieter Rosenthal
  • Patent number: 7229760
    Abstract: The present invention relates to a method for the amplification of mRNA of a sample, comprising the steps of i.) generating cDNA from polyadenylated RNA employing at least one primer hybridizing to said polyadenylated RNA and comprising a 5? poly(C) or a 5? poly(G) flank; ii.)(aa) if present, removing non-hybridized, surplus primer(s) and/or surplus dNTPs; ii.)(ab) 3? tailing of said generated cDNA with a poly(G) tail when in step i.(a) primer(s) comprising a 5? poly(C) flank was employed or a poly(C) tail when in step i.(a) primer(s) comprising a 5? poly(G) flank was employed; or ii.)(b) 3? tailing of said generated cDNA with a poly(G) tail when in step i.(a) primer(s) comprising a 5? poly(C) flank was employed or a poly(C) tail when in step i.(a) primer(s) comprising a 5? poly(G) flank was employed using an RNA-ligase, irrespective of the presence or absence of surplus primer(s) and/or surplus dNTPs; and iii.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: June 12, 2007
    Assignee: Micromet AG
    Inventors: Dietlind Zohlnhöfer, Christoph Klein
  • Publication number: 20060144981
    Abstract: The invention relates to a device for deflecting sections of strip, in particular metal strip, in a coiling plant, from a beginning guide channel (1) to an end guide channel (2) and vice-versa, comprising a driver (3) with a pair of driver rollers (4, 4?) and control elements arranged downstream in strip conveyance direction, comprising a switch (5) that can be swiveled towards the beginning guide channel (1) or the end guide channel (2), and a guide table (6) which is swivelably supported under the switch (5) and positionable as a wiper against the lower driver roller (4?).
    Type: Application
    Filed: November 25, 2003
    Publication date: July 6, 2006
    Inventors: Christoph Klein, Gunter Kneppe, Karl Hoen
  • Publication number: 20060138921
    Abstract: The invention concerns lamp elements which bear against each other at a separation plane and which can be releasably connected by way of a connecting means. To permit simple fixing of the lamp elements even in the overhead assembly procedure and to reduce the assembly time it is proposed in accordance with the invention that the lamp elements are each provided with respective contact pressure faces 22 and that the connecting means includes a bridge-like clamping portion 30 which in the installation position spans over the separation plane and has clamping contact pressure faces 32, 34 which in the installation position bear against the contact pressure faces 22 of the lamp elements (FIG. 3).
    Type: Application
    Filed: April 6, 2005
    Publication date: June 29, 2006
    Inventors: Christoph Klein, Rudolf Niggemann
  • Publication number: 20060000471
    Abstract: In an inhalation aid (1) to be used in connection with an aerosol dispenser, comprising a chamber designed with an opening (5) for connection to an aerosol dispenser and an opening (6) including a mouthpiece for drawing the aerosol, said chamber being designed with a variable volume, it is provided that the chamber is delimited by a conically tapering expansion bellows (2) made of a continuous, elastic material, whereby a simple and tight construction of the inhalation aid (1) is obtainable.
    Type: Application
    Filed: September 9, 2005
    Publication date: January 5, 2006
    Inventor: Christoph Klein
  • Publication number: 20040048816
    Abstract: The present invention relates to the use of a an inhibitor for the interferon &ggr; signaling pathway for the preparation of a pharmaceutical composition for the treatment or prevention of restenosis. Furthermore, the present invention provides for a method for the identification of an inhibitor of the IFN-&ggr; signaling pathway.
    Type: Application
    Filed: February 24, 2003
    Publication date: March 11, 2004
    Inventors: Dietlind Zohlnhfer, Patrick Bauerle, Christoph Klein, Franz-Josef Neumann
  • Publication number: 20040029124
    Abstract: The present invention relates to a method for the amplification of mRNA of a sample, comprising the steps of i.) generating cDNA from polyadenylated RNA employing at least one primer hybridizing to said polyadenylated RNA and comprising a 5′ poly(C) or a 5′ poly(G) flank; ii.)(aa) if present, removing non-hybridized, surplus primer(s) and/or surplus dNTPs; ii.)(ab) 3′ tailing of said generated cDNA with a poly(G) tail when in step i. (a) primer(s) comprising a 5′ poly(C) flank was employed or a poly(C) tail when in step i. (a) primer(s) comprising a 5′ poly(G) flank was employed; or ii.)(b) 3′ tailing of said generated cDNA with a poly(G) tail when in step i. (a) primer(s) comprising a 5′ poly(C) flank was employed or a poly(C) tail when in step i. (a) primer(s) comprising a 5′ poly(G) flank was employed using an RNA-ligase, irrespective of the presence or absence of surplus primer(s) and/or surplus dNTPs; and iii.
    Type: Application
    Filed: February 13, 2003
    Publication date: February 12, 2004
    Inventors: Dietlind Zohlnhofer, Christoph Klein
  • Patent number: 6673541
    Abstract: The present invention relates to a novel method for the amplification of DNA, this method being particularly useful for the amplification of the DNA or the whole genome of a single cell, chromosomes or fragments thereof. Described is also the use of the method in DNA analysis for medical, forensic, diagnostic or scientific purposes, like comparative genomic hybridization (CGH)-, fluorescence in situ hybridization (FISH)-, polymerase chain reaction (PCR)-, single strand conformation polymorphism (SSCP)-, DNA sequence-, “loss of heterozygosity” (LOH)-, fingerprint- and/or restriction fragment length polymorphism (RFLP)-analysis.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: January 6, 2004
    Assignee: Micromet AG
    Inventors: Christoph Klein, Oleg Schmidt-Kittler
  • Patent number: 5644128
    Abstract: A position sensitive fast timing detector for determining time-of-flight mass analysis and position of atomic particles includes a channel plate assembly for detecting the impact of one or more atomic particles a transforming them into one or more electron clouds. The electron cloud then passes through an electron detector which includes a meandric delay line located in front of a back plate. A second meandric delay line may also be utilized, wherein the second delay line is orthogonal with the first delay line. A grid may be placed between the first and second meandric delay lines to reduce cross-talk.
    Type: Grant
    Filed: August 25, 1994
    Date of Patent: July 1, 1997
    Assignee: Ionwerks
    Inventors: Hermann Wollnik, Christoph Klein
  • Patent number: 5435297
    Abstract: A medical device for inhaling metered aerosol has a cylindrical housing with a receiving chamber for receiving an aerosol container and first main air channels extending axially within the housing. A mouthpiece is coaxially connected to the housing. An atomizing and vortexing chamber is delimited by the housing and the mouthpiece. Second main air channels extend within the mouthpiece and communicate with the first main air channels. A partition is positioned between the receiving chamber and the atomizing and vortexing chamber. The partition has a stepped bore with a first section and a second section, the first section having a larger diameter than the second section. The first section opens into the receiving chamber and the second section opens into the atomizing and vortexing chamber to form an aerosol outlet. Branch air channels extend at a slant to an axial direction of the medical device within the partition so as to surround the stepped bore.
    Type: Grant
    Filed: June 29, 1994
    Date of Patent: July 25, 1995
    Assignees: Christoph Klein, Peter-Christian Sroka
    Inventor: Christoph Klein
  • Patent number: 5237325
    Abstract: A process and a system for multi-channel gathering and evaluation of measured data in which measured data channels are distinguished into analog data channels and into digital or event channels. By means of a signal derived from the events, or rather from event signals, and processed in the event channels the analog measured data are synchronously sampled, (i.e. picked up, converted into a digital value and stored). Each time an identification number is stored for the event signal triggering the sampling operation, or rather of the corresponding event channel, the phase time between this sampling signal and the preceding sampling signal, the associated sampled measured data and the time sequence of the sampling operations. The signal triggering the synchronous sampling operation is preferably formed by OR-linking of all event signals which are scaled down, if applicable.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: August 17, 1993
    Inventors: Hans-Christoph Klein, Peter Lohberg, Ludger Munch