Patents by Inventor Christoph Sommer

Christoph Sommer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10485880
    Abstract: The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: November 26, 2019
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Hans-Georg Lerchen, Sven Wittrock, Yolanda Cancho Grande, Beatrix Stelte-Ludwig, Anette Sommer, Sandra Berndt, Christoph Mahlert, Anne-Sophie Rebstock, Carsten Terjung, Simone Greven
  • Publication number: 20190351066
    Abstract: The invention relates to novel prodrugs or conjugates of the general formula (Ia) in which La, n, R and D have the definitions given in the description and which have a structural motif reduced to an asparagine derivative as cleavage site for tumour-associated proteases such as legumain, in which cytotoxic drugs, for example kinesin spindle protein inhibitors, are released by legumain cleavage, and to the use of these prodrugs or conjugates for treatment and/or prevention of diseases, and to the use of these prodrugs or conjugates for production of medicaments for treatment and/or prevention of diseases, especially of hyperproliferative and/or angiogenic disorders, for example cancers. Reduction of the legumain-cleavable substrate peptide sequence to an asparagine derivative as structural motif, as a result of slowed legumain cleavage, achieves an increase in stability in the lysosomes of healthy organs while simultaneously maintaining the high anti-tumour effect.
    Type: Application
    Filed: December 18, 2017
    Publication date: November 21, 2019
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Hans-Georg LERCHEN, Anne-Sophie REBSTOCK, Leo MARX, Sarah Anna Liesa JOHANNES, Beatrix STELTE-LUDWIG, Lisa DIETZ, Hannah JOERISSEN, Christoph MAHLERT, Simone GREVEN, Anette SOMMER
  • Publication number: 20190328897
    Abstract: The invention relates to novel binder-drug conjugates (ADCs) having improved properties, to active metabolites of these ADCs and to processes for their preparation. The present invention furthermore relates to the use of these conjugates for the treatment and/or prevention of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases.
    Type: Application
    Filed: December 14, 2017
    Publication date: October 31, 2019
    Applicants: Bayer Pharma Aktiengesellschaft, Bayer Aktiengesellschaft
    Inventors: Hans-Georg LERCHEN, Anne-Sophie REBSTOCK, Beatrix STELTE-LUDWIG, Dennis KIRCHHOFF, Lisa DIETZ, Christoph MAHLERT, Simone GREVEN, Stephan MÄRSCH, Sandra BERNDT, Anette SOMMER, Stefanie HAMMER
  • Patent number: 10436883
    Abstract: The present invention provides a time-of-flight sensor (22) including at least one time-of-flight pixel (23) for demodulating a received modulated light beam (Sp2), wherein the time-of-flight pixel (23) comprises at least two integrating nodes (Ga, Gb) and the integration nodes (Ga, Gb) are connected to a device (500) for charge compensation, wherein the charge compensation device (500) comprises at least two SBI input transistors (M1, M2) which at a potential (Ua, Ub) of the integration nodes (Ga, Gb) which according to the amount exceeds an SBI threshold value (USBI) drive SBI current transistors (M3, M4) such that at both integration nodes (Ga, Gb) a compensating current (ik) of the same level flows, wherein the source terminals of the SBI-current transistors (M3, M4) are not connected to a supply voltage (UDD) but are connected to a working voltage (URES, Uarb) (FIG. 7).
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: October 8, 2019
    Assignee: PMD Technologies AG
    Inventors: Michael Sommer, Jens Prima, Christoph Kamerow
  • Publication number: 20190262463
    Abstract: The invention relates to site specific homogeneous binder drug conjugates of kinesin spindle protein inhibitors, to active metabolites of these conjugates, to processes for preparing these conjugates, to the use of these conjugates for the treatment and/or prophylaxis of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.
    Type: Application
    Filed: June 20, 2016
    Publication date: August 29, 2019
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hans-Georg LERCHEN, Yolanda CANCHO GRANDE, Beatrix STELTE-LUDWIG, Anette SOMMER, Christoph MAHLERT, Anne-Sophie REBSTOCK, Simone GREVEN, Nils GRIEBENOW, Jan TEBBE, Oliver KENSCH
  • Publication number: 20180131241
    Abstract: Energy transmission device for the wireless transmission of energy to an active implant, comprising: a transmitter coil adapted for electrical connection to an energy source, and an implantable receiver coil adapted for inductive coupling to the transmitter coil for wireless energy transmission, wherein an implantable primary coil is electrically connected to a modulator, the modulator modulating an AC voltage supplied to the implantable primary coil based on a data signal so that data transmission from the implantable primary coil to an extracorporeal secondary coil is performed, the frequency of the data transmission being different from the frequency at which the energy is transmitted from the transmitter coil to the receiver coil, and wherein information regarding the energy control of the energy to be transmitted from the transmitter coil is transmitted from the primary coil to the secondary coil by a pulse width modulated signal, other information not regarding the energy control is transmitted by means
    Type: Application
    Filed: July 12, 2017
    Publication date: May 10, 2018
    Inventors: Heinz HORNUNG, Stefan SCHWARZBACH, Christian HABERSETZER, Dominik SCHUSTER, Soeren MICHEL, Christoph SOMMER, SR.
  • Patent number: 9353450
    Abstract: An electrolyzer apparatus for the electrolytic manufacture of elemental F2 from an electrolyte/HF-solution, e.g., KF×1.8 HF, comprising at least one electrolytic cell which contains at least two anodes, often 20 to 30 anodes, a metallic cathodic vessel, and at least two rectifiers such that each anode is allocated to one rectifier. In this manner, each anode can be controlled and regulated individually. Failure of each individual anode, e.g., anode break, causes the production of undesired side products, e.g., of CF4. Any faulty anode can be detected easily, and each anode can be shut off individually, if needed, and repaired.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: May 31, 2016
    Assignee: SOLVAY SA
    Inventors: Philippe Morelle, Joachim Lange, Christoph Sommer
  • Patent number: 8821821
    Abstract: Elemental fluorine is often manufactured electrochemically from a solution of KF in hydrogen fluoride and contains varying amounts of entrained electrolyte salt in solid form as impurity. The invention concerns a process for the purification of such impure elemental fluorine by contact with liquid hydrogen fluoride, e.g., in a jet gas scrubber or by bubbling the raw fluorine through liquid hydrogen fluoride. After this purification step, any entrained hydrogen fluoride is removed by adsorption, condensing it out or both. After passing through a filter with very small pores, the purified fluorine is especially suited for the semiconductor industry as etching gas or as chamber cleaning gas in the manufacture of semiconductors, TFTs and solar cells, or for the manufacture of micro-electromechanical systems (“MEMS”).
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: September 2, 2014
    Assignee: Solvay SA
    Inventors: Oliviero Diana, Peter M. Predikant, Philippe Morelle, Maurizio Paganin, Christoph Sommer
  • Publication number: 20130233723
    Abstract: An electrolyzer apparatus for the electrolytic manufacture of elemental F2 from an electrolyte/HF-solution, e.g., KF×1.8 HF, comprising at least one electrolytic cell which contains at least two anodes, often 20 to 30 anodes, a metallic cathodic vessel, and at least two rectifiers such that each anode is allocated to one rectifier. In this manner, each anode can be controlled and regulated individually. Failure of each individual anode, e.g., anode break, causes the production of undesired side products, e.g., of CF4. Any faulty anode can be detected easily, and each anode can be shut off individually, if needed, and repaired.
    Type: Application
    Filed: November 16, 2011
    Publication date: September 12, 2013
    Applicant: SOLVAY SA
    Inventors: Philippe Morelle, Joachim Lange, Christoph Sommer
  • Publication number: 20130130505
    Abstract: Elemental fluorine is often manufactured electrochemically from a solution of KF in hydrogen fluoride and contains varying amounts of entrained electrolyte salt in solid form as impurity. The invention concerns a process for the purification of such impure elemental fluorine by contact with liquid hydrogen fluoride, e.g., in a jet gas scrubber or by bubbling the raw fluorine through liquid hydrogen fluoride. After this purification step, any entrained hydrogen fluoride is removed by adsorption, condensing it out or both. After passing through a filter with very small pores, the purified fluorine is especially suited for the semiconductor industry as etching gas or as chamber cleaning gas in the manufacture of semiconductors, TFTs and solar cells, or for the manufacture of micro-electromechanical systems (“MEMS”).
    Type: Application
    Filed: August 3, 2011
    Publication date: May 23, 2013
    Applicant: SOLVAY SA
    Inventors: Oliviero Diana, Peter M. Predikant, Philippe Morelle, Maurizio Paganin, Christoph Sommer
  • Publication number: 20130023126
    Abstract: Elemental fluorine is used as etching agent for the manufacture of electronic devices, especially semiconductor devices, micro-electromechanical devices, thin film transistors, flat panel displays and solar panels, and as chamber cleaning agent mainly for plasma-enhanced chemical vapor deposition (PECVD) apparatus. For this purpose, fluorine often is produced on-site. The invention provides a process for the manufacture of electronic devices wherein fluorine is produced on site and is purified from HF by a low temperature treatment. A pressure of between 1.5 and 20 Bars absolute is especially advantageous.
    Type: Application
    Filed: April 7, 2011
    Publication date: January 24, 2013
    Applicant: SOLVAY SA
    Inventors: Christoph Sommer, Oliviero Diana, Johannes Eicher, Ercan Uenveren, Stefan Mross, Holger Pernice, Peter M. Predikant, Thomas Schwarze, Reiner Fischer
  • Publication number: 20120228144
    Abstract: An apparatus for producing a fluorine gas, comprising at least one fluorine generating cell, and at least one fluorine generating cell detector for detecting components of products obtained by the fluorine generating cell, wherein at least one of the fluorine generating cells is connected with the fluorine generating cell detector.
    Type: Application
    Filed: October 13, 2010
    Publication date: September 13, 2012
    Applicant: SOLVAY FLUOR GMBH
    Inventors: Holger Pernice, Johannes Eicher, Francis Feys, Dominique Balthasart, Christoph Sommer, Harald Krueger
  • Publication number: 20120157695
    Abstract: Crude fluoroethylene carbonate obtained by the fluorination of ethylene carbonate and elemental fluorine containing not more than 5% by weight of HF is purified by at least two subsequent distillation steps. The bulk of HF can be removed, if desired, in a preliminary HF removal step, e.g., by stripping, before performing the distillation. Further, if desired, a second HF removal step can be performed by contacting the crude mixture or the distillate obtained after the first distillation step with an adsorbent for HF, e.g., silica gel. The distillation can be performed batch wise. It is preferred to perform the distillation continuously. It yields purified fluoroethylene carbonate with an HF content of equal to or less than 30 ppm. The purified fluoroethylene carbonate can be applied as solvent additive for lithium ion batteries.
    Type: Application
    Filed: August 17, 2010
    Publication date: June 21, 2012
    Applicant: SOLVAY FLUOR GMBH
    Inventors: Alain Lambert, Christoph Sommer, Harald Krueger, Jens Olschimke
  • Patent number: 8075534
    Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: December 13, 2011
    Assignee: TecPharma Licensing AG
    Inventors: Stefan Burren, Ulrich Moser, Christian Schrul, Christoph Sommer
  • Publication number: 20110009660
    Abstract: Mixtures comprising organic carbonates, such as carbonates not substituted by fluorine, but especially fluorosubstituted organic carbonates, which are depleted in HF can be obtained from respective mixtures with a higher HF content by a step of stripping such mixture with an inert gas. For example, a reaction mixture comprising fluoroethylene carbonate and HF can be treated in this way. The mixture comprising organic carbonate which is depleted in HF can be distilled to obtain highly purified organic carbonate.
    Type: Application
    Filed: March 26, 2009
    Publication date: January 13, 2011
    Applicant: SOLVAY FLOUR GMBH
    Inventors: Harald Krueger, Christoph Sommer, Alain Lambert, Phillip Schwerdt, Jens Olschimke, Dirk Seffer, Saskia Wedekind
  • Publication number: 20100286624
    Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.
    Type: Application
    Filed: July 20, 2010
    Publication date: November 11, 2010
    Inventors: Stefan Burren, Ulrich Moser, Christian Schrul, Christoph Sommer
  • Patent number: 7828779
    Abstract: An injection device including a housing with a reservoir for an injectable product, a delivery device used to dispense a product dose from the reservoir, and a dose metering member which, in order to select the product dose, can carry out a rotational displacement in relation to the housing in a first direction until it reaches an end position and can be displaced in an opposite second rotational direction, wherein the dose metering member is coupled to the delivery device in such a way that the latter, when actuated, dispenses the product dose that has been selected by means of the dose metering member, the injection device also including an anti-twist safety device which has at least one anti-twist stop and at least one anti-twist counter-stop, one of which is formed by the housing and the other by the dose-metering member, wherein the anti-twist stop and the anti-twist counter-stop come to rest against one another in the end position in order to prevent the rotational displacement of the dose metering memb
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: November 9, 2010
    Assignee: TecPharma Licensing AG
    Inventors: Fritz Kirchhofer, Michael Schaer, Christoph Sommer
  • Patent number: 7771399
    Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: August 10, 2010
    Assignee: TecPharma Licensing AG
    Inventors: Stefan Burren, Ulrich Moser, Christian Schrul, Christoph Sommer
  • Publication number: 20070167921
    Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.
    Type: Application
    Filed: October 19, 2006
    Publication date: July 19, 2007
    Inventors: Stefan Burren, Ulrich Moser, Christian Schrul, Christoph Sommer
  • Publication number: 20070154376
    Abstract: Sulphuryl fluoride may comprise carbon dioxide. It has now been found that the carbon dioxide can be removed from the sulphuryl fluoride by means of molecular sieve.
    Type: Application
    Filed: February 9, 2005
    Publication date: July 5, 2007
    Applicant: Solvay Fluor GmbH
    Inventor: Christoph Sommer