Patents by Inventor Christopher David Gwenin

Christopher David Gwenin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190250160
    Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is a mycolic acid wax ester derived antigen.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 15, 2019
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al Dulayymi, Salam Ghafour Taher
  • Publication number: 20180231547
    Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is an arabinose ester of a mycolic acid or an analogue thereof.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 16, 2018
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al-Dulayymi, Mohsin Omar Mohammed
  • Patent number: 9945852
    Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the color of the sample.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: April 17, 2018
    Assignee: Arcis Biotechnology Holdings Limited
    Inventors: Christopher David Gwenin, Mark Stephen Baird, Vanessa Valerie Gwenin, Mark Pitts
  • Publication number: 20170248595
    Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising the steps of (a) providing a porous substrate which carries an antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a composition comprising a secondary antibody; and (d) observing the substrate. The method may enable a very quick, simple test to be carried out to determine whether or not a particular sample contains a biomarker, for example an antibody indicative of infection with a mycobacterial disease. A kit and a device for determining the presence or absence in a sample of a biomarker are also described.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 31, 2017
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Joanne Louise Hacking, Mark Pitts
  • Publication number: 20170242005
    Abstract: A method of determining whether an individual is infected with mycobacteria. The method comprising the steps of (a) providing a system which comprises at least two different mycolic-acid derived antigens; (b) introducing a sample obtained from the individual into the system and into contact with each of the at least two different mycolic-acid derived antigens; and (c) detecting the presence or absence of the binding of a biomarker in the sample with each antigen in the system. The method may be particularly suitable for determining the presence or absence of a disease antibody indicative of infection with any disease caused by infection with mycobacteria, for example tuberculosis, leprosy, pulmonary disease, burili ulcer, Johne's disease and bovine tuberculosis. A kit and device are also described. The present invention may provide an over the counter device to allow individuals to check on a routine basis that they have normal immune responses.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 24, 2017
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Alison Jones
  • Patent number: 9506921
    Abstract: A method of determining the presence or absence in a sample of a biomarker indicative of exposure to mycobacteria, the method comprising: (a) providing a substrate carrying a mycolic acid derived antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a fluorophore species; (d) creating an evanescent wave at the boundary of the substrate and the sample; (e) detecting the presence or absence of fluorescence.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: November 29, 2016
    Assignee: Bangor University
    Inventors: Christopher David Gwenin, Mark Stephen Baird
  • Publication number: 20140127709
    Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the colour of the sample.
    Type: Application
    Filed: May 4, 2012
    Publication date: May 8, 2014
    Applicant: Bangor University
    Inventors: Christopher David Gwenin, Mark Stephen Baird, Vanessa Valerie Gwenin, Mark Pitts
  • Publication number: 20140051599
    Abstract: A method of determining the presence or absence in a sample of a biomarker indicative of exposure to mycobacteria, the method comprising: (a) providing a substrate carrying a mycolic acid derived antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a fluorophore species; (d) creating an evanescent wave at the boundary of the substrate and the sample; (e) detecting the presence or absence of fluorescence.
    Type: Application
    Filed: March 30, 2012
    Publication date: February 20, 2014
    Applicant: Bangor University
    Inventors: Christopher David Gwenin, Mark Stephen Baird
  • Publication number: 20090120809
    Abstract: This invention provides a sensing device comprising an electrode comprising a noble metal layer, on which layer is located a biological material having nitroreductase activity. This invention further provides a method of detecting nitro group containing compounds, the method comprising the steps of: (a) providing a sensing device of the first aspect of the invention and a reference electrode; (b) applying a potential between the electrodes; (c) measuring the current; (d) contacting the sensing device with a sample of substrate material to be tested; and (e) measuring the current change.
    Type: Application
    Filed: November 17, 2004
    Publication date: May 14, 2009
    Applicants: UNIVERSITY OF WALES, BANGOR, TRWYN LIMITED
    Inventors: Maher Kalaji, Peter Anthony Williams, Christopher David Gwenin