Patents by Inventor Christopher M. Smales

Christopher M. Smales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Means and methods for the generation of mammalian producer cells for the production of recombinant proteins
    Patent number: 10669541
    Abstract: Methods for generating mammalian cells characterized by an increased concentration of at least one of miR-15, miR-16, and miR-34 for producing proteins at an industrial scale are provided. Methods for using the mammalian cells, in particular for the production of proteins of interest, are also provided.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: June 2, 2020
    Assignee: LONZA BIOLOGICS PLC.
    Inventors: Marc Feary, James Rance, Robert Young, Elizabeth C. Sayer, Christopher M. Smales
  • Rapid method for targeted cell (line) selection
    Patent number: 10139418
    Abstract: The present invention relates to a process for the prediction of cell culture performance data of sample cells, a process for the isolation of said cells and a device for the prediction of cell culture performance data of sample cells.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: November 27, 2018
    Assignee: LONZA BIOLOGICS PLC
    Inventors: Dietmar Lang, Elaine B. Martin, Gary A. Montague, Christopher J. O'Malley, Tracy S. Root, Carol M. Trim, Jane F. Povey, Christopher M. Smales, Andrew J. Racher
  • Rapid Method For Targeted Cell (Line) Selection
    Publication number: 20170242029
    Abstract: The present invention relates to a process for the prediction of cell culture performance data of sample cells, a process for the isolation of said cells and a device for the prediction of cell culture performance data of sample cells.
    Type: Application
    Filed: March 17, 2017
    Publication date: August 24, 2017
    Applicant: LONZA BIOLOGICS PLC
    Inventors: Dietmar LANG, Elaine B. MARTIN, Gary A. MONTAGUE, Christopher J. O'MALLEY, Tracy S. ROOT, Carol M. TRIM, Jane F. POVEY, Christopher M. SMALES, Andrew J. RACHER
  • MEANS AND METHODS FOR THE GENERATION OF MAMMALIAN PRODUCER CELLS FOR THE PRODUCTION OF RECOMBINANT PROTEINS
    Publication number: 20160177300
    Abstract: The present invention relates to the generation of mammalian cells capable of producing proteins at an industrial scale and means and methods to obtain and use said cells, in particular for protein production.
    Type: Application
    Filed: July 30, 2014
    Publication date: June 23, 2016
    Applicant: LONZA BIOLOGICS PLC
    Inventors: Marc FEARY, James RANCE, Robert YOUNG, Elizabeth C. SAYER, Christopher M. SMALES
  • RAPID METHOD FOR TARGETED CELL (LINE) SELECTION
    Publication number: 20130295596
    Abstract: The present invention relates to a process for the prediction of cell culture performance data of sample cells, a process for the isolation of said cells and a device for the prediction of cell culture performance data of sample cells.
    Type: Application
    Filed: October 27, 2011
    Publication date: November 7, 2013
    Applicant: LONZA BIOLOGICS PLC
    Inventors: Dietmar Lang, Elaine B. Martin, Gary A. Montague, Christopher J. O'Malley, Tracy S. Root, Carol M. Trim, Jane F. Povey, Christopher M. Smales, Andrew J. Racher