Patents by Inventor Claas Aiko Meyer

Claas Aiko Meyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR ASSESSING TRANSENDOTHELIAL BARRIER INTEGRITY
    Publication number: 20210247385
    Abstract: This application relates to a method for identifying a drug candidate capable of increasing or decreasing barrier tissue integrity of endothelial cells. Moreover, this application relates to the use of a tight junction gene transcriptional reporter as a surrogate marker of transendothelial barrier integrity.
    Type: Application
    Filed: February 19, 2021
    Publication date: August 12, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Chad A. COWAN, Claas Aiko MEYER, Filip ROUDNICKY, Jitao David ZHANG
  • SYNERGISTIC TRANSCRIPTION FACTORS TO INDUCE HIGH RESISTANCE TRANSENDOTHELIAL BARRIER
    Publication number: 20210222122
    Abstract: This application relates to transcription factors capable of increasing transendothelial barrier integrity. Moreover, this application relates to the use of vectors encoding such transcription factors and cells comprising such vectors.
    Type: Application
    Filed: April 9, 2021
    Publication date: July 22, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Chad A. COWAN, Claas Aiko MEYER, Filip ROUDNICKY
  • Inflammation in vivo model
    Patent number: 9271479
    Abstract: The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimizing the pharmacological properties of a given anti-inflammatory compound.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: March 1, 2016
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Javier Cote-Sierra, Antonio Iglesias, Claas Aiko Meyer
  • Novel Inflammation in Vivo Model
    Publication number: 20150026832
    Abstract: The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimising the pharmacological properties of a given anti-inflammatory compound.
    Type: Application
    Filed: September 3, 2014
    Publication date: January 22, 2015
    Inventors: Javier Cote-Sierra, Antonio Iglesias, Claas Aiko Meyer
  • Novel Inflammation to vivo model
    Publication number: 20130318641
    Abstract: The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimising the pharmacological properties of a given anti-inflammatory compound.
    Type: Application
    Filed: April 22, 2013
    Publication date: November 28, 2013
    Inventors: Javier Cote-Sierra, Antonio Iglesias, Claas Aiko Meyer