Patents by Inventor Claes Friberg
Claes Friberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7431916Abstract: A method of administering a metered dry powder combined dose of finely divided dry medication powders is disclosed, wherein said method comprises providing a relative motion between a nozzle of a dry powder inhaler and a dose bed carrying said combined dose of finely divided dry medication powder intended for delivery by the dry powder inhaler, the combined dose comprises metered quantities of at least two medicaments separately deposited on the dose bed, the relative motion causing the nozzle to pass over the combined dose for a simultaneous or sequential delivery of the medicaments during the course of a single suction of air.Type: GrantFiled: June 26, 2003Date of Patent: October 7, 2008Assignee: Mederio AGInventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Publication number: 20080202630Abstract: A method and an apparatus for exact metering and volumetric filling of dry powder medicament doses into preformed containers, which are adapted for administration by a dry powder inhaler. The filling apparatus includes at least a bulk powder source, a feeding chamber, and a receptacle providing the volume for a specified load mass of dry powder. The bulk powder source releases a portion of powder discontinuously to the feeding chamber, but is disconnected from the feeding chamber and receptacle during the filling operation. The filling apparatus further presents a plane surface in contact with the movable feeding chamber and provides a hard-wearing, low friction coating for reducing dynamic friction and powder retention.Type: ApplicationFiled: February 8, 2005Publication date: August 28, 2008Applicant: Mederio AGInventors: Lars Kax, Claes Friberg
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Publication number: 20080023098Abstract: The invention discloses a method and a tool for exact metering and volumetric filling of finely divided dry powder medicament doses into preformed containers, whereby the doses and containers are adapted for administration by inhalation using a dry powder inhaler (DPI). A filling tool illustrating the invention includes at least one receptacle (10). The shape and size of a receptacle may vary depending on the size and mass of the powder load to be metered. A stretched woven filter (106) is positioned between the second opening of the receptacle (10) and a suction nozzle (13), using flexible seals at joints to stop air and powder leakage. The shape may be circular or elliptical, the wideness and depth, i.e. the volume, is adapted to the intended load and the method of filling and unloading.Type: ApplicationFiled: May 18, 2006Publication date: January 31, 2008Applicant: MEDERIO AGInventors: Claes Friberg, Lars Kax
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Publication number: 20060239933Abstract: A medical product is disclosed. The medical product contains an accurately metered dose of at least one GLP medicament intended for pulmonary inhalation put into a moisture-tight, high barrier seal container. The medical product optionally also contains a dose of insulin. The container is adapted for application into a dry powder inhaler. The dose loaded in the container is intended for a prolonged delivery by inhalation to the deep lung where the active ingredients are absorbed into the system. Optionally the medical product also may comprise at least one biologically acceptable excipient.Type: ApplicationFiled: November 15, 2005Publication date: October 26, 2006Applicant: MEDERIO AGInventors: Thomas Nilsson, Sven Calander, Alf Niemi, Claes Friberg, Lars Kax, Mattias Myrman
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Patent number: 7069963Abstract: The invention discloses a method and a tool for exact metering and volumetric filling of finely divided dry powder medicament doses into preformed containers, whereby the doses and containers are adapted for administration by inhalation using a dry powder inhaler (DPI). A filling tool illustrating the invention includes at least one receptacle (10). The shape and size of a receptacle may vary depending on the size and mass of the powder load to be metered. A stretched woven filter (106) is positioned between the second opening of the receptacle (10) and a suction nozzle (13), using flexible seals at joints to stop air and powder leakage. The shape may be circular or elliptical, the wideness and depth, i.e. the volume, is adapted to the intended load and the method of filling and unloading.Type: GrantFiled: February 13, 2004Date of Patent: July 4, 2006Assignee: Mederio AGInventors: Claes Friberg, Lars Kax
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Publication number: 20060120969Abstract: A medical product containing an accurately metered dose of a GLP-1 medicament intended for pulmonary inhalation put into a moisture-tight, high barrier seal container. The medical product optionally also contains a dose of insulin. The container is preferably adapted for application into a dry powder inhaler. The dose loaded in the container is intended for a prolonged delivery by inhalation to the deep lung where the active ingredients are absorbed into the system. Optionally the medical product also may comprise at least one biologically acceptable excipient.Type: ApplicationFiled: February 4, 2005Publication date: June 8, 2006Applicant: Microdrug AGInventors: Thomas Nilsson, Sven Calander, Alf Niemi, Claes Friberg, Lars Kax, Mattias Myrman
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Publication number: 20060067911Abstract: The invention discloses a metered medication dose of a dry powder protein medicament, particularly a peptide medicament, intended for inhalation by use of an adapted dry powder inhaler. An active peptide agent is presented in a pure, natural, crystalline, micronized, dry powder form. A dose comprises at least one such peptide powder and may optionally comprise at least one biologically acceptable excipient in dry powder form. The dose does not include any substances that are intended to change one, some or all properties of the at least one peptide with an object of improving the stability or systemic absorption of the active peptide or peptides deposited.Type: ApplicationFiled: April 22, 2005Publication date: March 30, 2006Applicant: MEDERIO AGInventors: Thomas Nilsson, Claes Friberg, Lars Kax, Alf Niemi, Mattias Myrman, Sven Calander
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Publication number: 20050279356Abstract: A medicament container for carrying a metered, finely divided, dry powder medication dose is disclosed. The medicament container, which is intended for administration by a dry powder inhaler device, constitutes a pod presents a bottom surface acting as a dose bed adapted for receiving a metered medication dose. The metered dose, carried by the pod, is protected from foreign matter, particularly moisture, after a sealing of the pod with a high barrier seal foil, which transforms the pod into a high barrier container. Furthermore the pod is formed such that the pod sealing foil can be slit open from a point of penetration at a first pod end to a point of exit at a second pod end by a cutter set in motion relative to the pod.Type: ApplicationFiled: July 26, 2004Publication date: December 22, 2005Applicant: Microdrug AGInventors: Claes Friberg, Lars Kax, Mattias Myrman
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Publication number: 20050211244Abstract: A dry powder medicament preparation is disclosed. Also methods of forming and loading metered doses of the preparation into dose containers intended for insertion into a dry powder inhaler are disclosed. The preparation is adapted for a dose forming process, which may be based on volumetric filling or electro-dynamic deposition of the powder particles, such that a metered dose of the preparation is characterized by having at least one load of held-together particles joined in a macrostructure of predefined dimensions and presenting an intended mechanical strength. The pharmacologically active ingredient presents at least 50% by mass of particles in a typical aerodynamic diameter range from 1 to 5 ?m. Furthermore, a dose thus formed is then loaded into a high barrier container.Type: ApplicationFiled: March 22, 2005Publication date: September 29, 2005Applicant: MEDERIO AGInventors: Thomas Nilsson, Claes Friberg, Lars Kax, Alf Niemi, Sven Calander
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Publication number: 20050173552Abstract: The invention discloses a method and a tool for exact metering and volumetric filling of finely divided dry powder medicament doses into preformed containers, whereby the doses and containers are adapted for administration by inhalation using a dry powder inhaler (DPI). A filling tool illustrating the invention includes at least one receptacle (10). The shape and size of a receptacle may vary depending on the size and mass of the powder load to be metered. A stretched woven filter (106) is positioned between the second opening of the receptacle (10) and a suction nozzle (13), using flexible seals at joints to stop air and powder leakage. The shape may be circular or elliptical, the wideness and depth, i.e. the volume, is adapted to the intended load and the method of filling and unloading.Type: ApplicationFiled: February 13, 2004Publication date: August 11, 2005Applicant: Microdrug AGInventors: Claes Friberg, Lars Kax
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Publication number: 20050063911Abstract: The present invention discloses pharmaceutical dry powder combined doses for the administration by inhalation of metered dry powder combined doses of finely divided dry medication powders. Formoterol and an anticholinergic agent are selected medicaments for forming the combined doses. Metered dry powder medicinal combined doses comprising separately metered deposits of medicinally suitable quantities of each of the selected medicaments are prepared, in which the sum of the metered deposits constitutes the metered quantities of powder of the combined doses and the medicinal combined doses are introduced into an adapted inhaler device for a generally simultaneous or sequential delivery of the medicinal combined doses during the course of a single inhalation by a user, such that each one of the delivered medicinal combined doses is composed of a high proportion of de-aggregated fine particles of the selected medicament or medicaments, whereby a desired therapeutic or treating effect to the user is achieved.Type: ApplicationFiled: June 21, 2004Publication date: March 24, 2005Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Publication number: 20050053553Abstract: The present invention discloses a method and pharmaceutical dry powder combined doses for administration by inhalation of metered dry powder combined doses of finely divided dry medication doses. Formoterol and fluticasone are selected medicaments for forming the combined doses. Metered dry powder medicinal combined doses comprising separately metered deposits of medicinally effective quantities of each of the selected medicaments are prepared, in which the sum of the metered deposits constitutes the metered quantities of powder of the combined doses and the medicinal combined doses are introduced into an adapted inhaler device for a generally simultaneous or sequential prolonged delivery of the medicinal combined doses during the course of a single inhalation by a user, such that each one of the administered medicinal combined doses is composed of a high proportion of de-aggregated fine particles of the selected medicament or medicaments and directed to a selected location in the lungs.Type: ApplicationFiled: November 10, 2003Publication date: March 10, 2005Inventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Publication number: 20050042175Abstract: The present invention discloses pharmaceutical dry powder combined doses for administration by inhalation of metered dry powder combined doses of finely divided dry medication doses. Formoterol and budesonide are selected medicaments for forming the combined doses. Metered dry powder medicinal combined doses comprising separately metered deposits of medicinally effective quantities of each of the selected medicaments are prepared, in which the sum of the metered deposits constitutes the metered quantities of powder of the combined doses and the medicinal combined doses are introduced into an adapted inhaler device for a generally simultaneous or sequential prolonged delivery of the medicinal combined doses during the course of a single inhalation by a user, such that each one of the administered medicinal combined doses is composed of a high proportion of de-aggregated fine particles of the selected medicament or medicaments and directed to a selected location in the lungs of a user.Type: ApplicationFiled: June 21, 2004Publication date: February 24, 2005Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Publication number: 20050042174Abstract: A method and pharmaceutical dry powder combination of doses for the prophylaxis or treatment of a respiratory disorder in a user by inhalation of metered dry powder combinations of doses of finely divided dry medication powders. Medicaments for forming a combination of doses are selected from a group of beta2-agonists, a group of anticholinergic agents and a group of anti-inflammatory corticosteroids. Metered dry powder medicinal combinations of doses comprising separately metered deposits of medicinally suitable quantities of each of the selected medicaments are prepared. The medicinal combination of doses are introduced into an adapted inhaler device for a generally simultaneous or sequential delivery during the course of a single inhalation by a user, such that each one of the delivered medicinal combination of doses is composed of a high proportion of de-aggregated fine particles of the selected medicament or medicaments.Type: ApplicationFiled: June 21, 2004Publication date: February 24, 2005Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Publication number: 20040258625Abstract: A method as well as a therapeutic metered combined dose are disclosed for a combined administration of medicinal dry powders. A metered medicinal dry powder combined dosage comprising at least two medicaments of separate dry powder formulations is prepared, whereby the metered powder quantity per medicament is deposited in a dose forming step creating the medicinal combined dose. The deposits of the at least two medicaments are suitably kept separated from each other, such that the medicaments cannot detrimentally interact after forming of the combined dose, and the medicinal combined dose is introduced into an inhaler device for a delivery of the powder dose during the course of a single inhalation.Type: ApplicationFiled: June 26, 2003Publication date: December 23, 2004Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Publication number: 20040258624Abstract: The present invention discloses a method and a pharmaceutical dry powder combined dose for the prophylaxis or treatment of a respiratory disorder in a mammalian host by inhalation of a metered dry powder combined dose of finely divided dry medication powders. At least one dry powder medicament is selected from a first group of bronchodilating medicaments and at least one dry powder medicament from a second group of anti-inflammatory medicaments.Type: ApplicationFiled: June 26, 2003Publication date: December 23, 2004Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Claes Friberg, Sven Calander
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Patent number: D454781Type: GrantFiled: April 6, 2001Date of Patent: March 26, 2002Assignee: AstraZeneca ABInventors: Christian Assargren, Claes Friberg
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Patent number: D455344Type: GrantFiled: April 6, 2001Date of Patent: April 9, 2002Assignee: AstraZeneca ABInventors: Christian Assargren, Claes Friberg
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Patent number: D455345Type: GrantFiled: April 6, 2001Date of Patent: April 9, 2002Assignee: AstraZeneca ABInventors: Christian Assargren, Claes Friberg
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Patent number: D455953Type: GrantFiled: April 6, 2001Date of Patent: April 23, 2002Assignee: AstraZeneca ABInventors: Christian Assargren, Claes Friberg