Abstract: An injection device for injection of set doses of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member. A rotational coupling mechanism includes an axially displaceable coupling member which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.

Abstract: An injection device (1) for injecting a dose of drug, e.g. insulin for diabetes treatment, in which energy is stored in a spring member (9, 24) during dose setting. The stored energy is released and used for driving an injection mechanism during injection of a previously set dose. The injection device (1) further comprises means for electronically detecting the amount of a set dose and/or means for electronically detecting the amount of an injected dose. The electronic detecting means allows storage and/or logging of data relating to injections performed using the injection device (1).

Abstract: The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a dose setting member (20, 70) which is screwed out from the housing (30) to set a dose and pushed axially back to the housing (30) in order to expel the set dose. A scale drum (80) is axially and inrotatable coupled to the dose setting member (20, 70) such that the scale drum (80) is rotated up a thread (34) when the dose setting member (20, 70) is rotated to set a dose. When the dose setting member (20, 70) is pushed axially back to its initial position to inject the set dose, the scale drum (80) is released from its inrotatable connection in order to allow the scale drum (80) to rotate down the thread (34) and back to its zero position.

Abstract: A dosing assembly (204) and/or a container (202) comprising fastening means (206,208) for fastening the container to the dosing assembly, the fastening means of the dosing assembly and/or the container defining an asymmetrical pattern in a plane transverse to an axial direction of the dosing assembly and/or a container.

Abstract: An injection device comprising a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and mode locking means. The mode locking means is adapted to be in a first extreme position and in a second extreme position. When the mode locking means is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking means is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking means is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose. It is ensured that the liquid drug is not inadvertently expelled during dose setting and that blood or other body fluids is not sucked into the injection device during injection. Furthermore, inadvertent changing of the set dose during injection is prevented.

Abstract: An injection device with a gearing arrangement providing a gearing ratio between axial movement of an injection button and axial movement of a piston rod. The injection device comprises a dose setting member being operable to set a dose by rotating the dose setting member relatively to a housing, about a rotational axis. During setting of a dose the gearing arrangement is prevented from rotating along with the dose setting member about the rotational axis. Thereby the space which it is necessary to accommodate to the gearing arrangement inside the housing is reduced. This provides the possibility of using this space for other purposes, such as additional electronic components, designing the injection device in a manner which is appropriate for other purposes, e.g. with a relatively flat cross section, or reducing the overall size of the injection device. According to one aspect of the invention, the gearing arrangement comprises at least one gear wheel having a rotational axis which is non-parallel to, e.g.

Abstract: The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Abstract: A dose setting element for an injection device, comprising a first part being adapted to rotate during setting of a dose, and a second part being adapted to engage with the first part. Each time the first part has been rotated through a first specific angle the second part is caused to rotate through a second specific angle being smaller than the first specific angle. Keeps track of the total dose set since a cartridge was inserted. When the second part has been rotated a predefined number of times is abuts a stop, thereby preventing further dose setting. Prevents setting of a dose beyond an amount remaining in the cartridge. It is not necessary that part of the limiting mechanism travels a distance corresponding to the total dose due to the two separate parts. This allows the dose setting element and injection device to be small as compared to prior art dose limiting mechanisms. Further, an injection device comprising the dose setting element. Suitable for self-injection, e.g. of insulin.

Abstract: An injection device for injection of set doses of medicine from a cartridge has a nut (13) that is screwed up along a threaded piston rod (4) during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member (17. A rotational coupling mechanism includes an axially displaceable coupling member (25) which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.

Abstract: An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating.

Abstract: The application concerns an injection device for apportioning set doses of a drug from a reservoir (40) to a subject. The injection device comprises a housing having an interior thread (101,112) formed as an outwardly pointing thread (101,112) carried on an upstanding tower centrally located in the pen shaped device. This outwardly pointing thread (101,112) forms a first thread connection with the interior thread of the rotatable scale drum (90). The injection device further comprises a driver (70) for moving the piston rod (120) forward when moved axially. The driver (70) operates the piston rod (120) through a second thread connection having a pitch different than the first thread connection.

Abstract: A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The member receives a force from a user and drives the piston in the distal direction to expel medication. A intermediate system is disposed between the member and the piston including a gear set that has a pinion in meshed engagement with a rack. The system allows the member to move a greater distance than the piston moves thereby increasing the force on the piston.

Abstract: A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device comprises a threaded piston rod, a limiter and a driver. The three elements are arranged such that during dose setting, the limiter is moved towards an end-of-contend position, wherein dose setting is limited. The invention comprises an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for prevention ejection of a dose exceeding the set dose.

Abstract: A syringe device for ejecting a dose of a medicament, the syringe device comprising: a dose limiting mechanism arranged to interact with a dose ejecting mechanism to prevent ejection of a dose exceeding a set dose, and a safety mechanism, which is arranged such with respect to the dose ejecting mechanism that, if the dose limiting mechanism fails, the safety mechanism prevents ejection of a dose exceeding the set dose.

Abstract: An injection device for injection of set dose of liquid medicine from a cartridge has a piston rod (4, 104)/nut (3, 113) assembly where a nut is screwed up along a threaded piston rod during a dose setting operation. During administration of the set dose the nut is also screwed along the piston rod, thus making the piston rod/nut assembly either longer or shorter. During dose setting the nut is screwed along the piston rod by rotating a dose setting drum (17). An injection button is coupled to the piston rod with a gear wheel transmission (9, 109). Movement of the injection button causes a corresponding movement of the piston rod until the nut engages an abutment in the housing (1).

Abstract: The present invention relates to a method of assembling a syringe device such that rotational and translational tolerances are reduced or eliminated. The syringe device comprises a rotational retaining mechanism arranged to prevent backwards movement of a piston rod. The method comprises the step rotating the rotational retaining mechanism into a locking position prior to completing the assembly. Furthermore, the invention relates to a syringe device comprising a retaining mechanism having a first part and a second part, said parts being interconnected by a plurality of elements, wherein one of said elements comprises a first part and a second part separated by an interconnecting seam.

Abstract: A dose setting mechanism for an injection device, e.g. for repetitive self-injection of e.g. insulin or growth hormone. Has a dose setting member, a driving element for causing a set dose to be injected, and a locking member being connected to the driving element. The position of the locking member is indicative of the remaining amount of liquid in a cartridge. When the amount is below a critical lower value, the locking member assumes a locking position where it prevents the dose setting member from being operated to set a dose. Ensures that a dose can only be set if the remaining amount of liquid in the cartridge is sufficient to ensure proper mixing of the contents of the liquid. At the same time ensures optimal usage of the available liquid. Particularly suitable for injection devices for long acting or mix insulin.

Abstract: A dose setting mechanism for an injection device having a rotatably operated dose setting member. Has a presetting member being operable to limit the maximum dose settable by the dose setting member. A first stopping member is operatively connected to the presetting member, and the position of the first stopping member indicates the preset maximum dose. The first stopping member is adapted to rotatably engage with a second stopping member when the preset maximum dose has been set, thereby preventing setting of a further dose. The first and/or the second stopping member is/are movable along with the dose setting member, the first and second stopping members thereby being moved into engagement when a dose is set. Thereby a dose can be preset and the preset dose can easily be repeatedly set while ensuring an accurate dosage. Helps persons being visually impaired or having poor dexterity in setting a correct and accurate dose.

Abstract: The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising dial-up cam arranged to receive and engage with a dial-up key, wherein the dial-up cam and the dial-up key are adapted to, upon rotation of a dose setting member in a first direction, cooperate to strain the torsion spring of the injection device, and a dial-down cam arranged to receive and engage with a dial-down key, wherein the dial-down cam and the dial-down key are adapted to, upon rotation of the dose setting member in a second direction, cooperate to release the torsion spring of the injection device, the second rotation direction being opposite to the first rotation direction.

Abstract: An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to the set dose is shown in a window in the housing of the syringe, and an injection button, which is elevated over the end of the syringe, are moved axially a distance which is larger than the axial movement of the nut. A gear wheel gear transmission is established between the nut and the injection button.