Patents by Inventor Claus Schneider

Claus Schneider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4843086
    Abstract: This invention relates to new tetrahydrobenzthiazoles of general formula ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the above mentioned phenyl nuclei may each be substituted by 1 or 2 halogen atoms.R.sub.2 represents a hydrogen atom or an alkyl group,R.sub.3 represents a hydrogen atom, an alkyl group a cycloalkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the phenyl nucleus may be substituted by fluorine, chlorine or bromine atoms,R.sub.4 represents a hydrogen atom, an alkyl group, an alkyl or alkenyl group, orR.sub.3 and R.sub.4 together with the nitrogen atom between them represent a pyrrolidino, piperidino, hexamethyleneimino or morpholino group, the enantiomers and the acid addition salts thereof.The compounds of general formula I above in which one of the groups R.sub.1 or R.sub.3 or both groups R.sub.1 and R.sub.
    Type: Grant
    Filed: November 23, 1987
    Date of Patent: June 27, 1989
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerhart Griss, deceased, Claus Schneider, Rudolf Hurnaus, Walter Kobinger, Ludwig Pichler, Rudolf Bauer, Joachim Mierau, Dieter Hinzen, Gunter Schingnitz
  • Patent number: 4833140
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms;R.sub.2 is 2-, 3- or 4-pyridyl, phenyl or mono- or disubstituted phenyl, where the substituents are each individually alkoxy of 1 to 2 carbon atoms, fluorine, chlorine, bromine, trifluoromethyl, alkyl or 1 to 4 carbon atoms, hydroxyl or nitro; andR.sub.3 and R.sub.4 are each independently hydrogen or alkyl of 1 to 4 carbon atoms; orR.sub.3 and R.sub.4, together with each other and the nitrogen atom to which they are attached, form an unsubstituted or methyl-substituted, saturated 5- or 6-membered heterocycle which may contain an additional oxygen or nitrogen heteroatom, or form an imidazole ring;where the aminomethyl substituent is attached to the 4- or 5-position or the pyrrolidine ring, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as nootropics and antihypoxics.
    Type: Grant
    Filed: May 26, 1988
    Date of Patent: May 23, 1989
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Gerhard Walther, Claus Schneider, Dieter Hinzen, Franz J. Kuhn, Erich Lehr
  • Patent number: 4812453
    Abstract: The invention relates to the use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants.
    Type: Grant
    Filed: September 29, 1987
    Date of Patent: March 14, 1989
    Assignee: Boehringer Ingelheim KG
    Inventors: Erich Lehr, Wolf-Dietrich Bechtel, Karin Boke-Kuhn, Claus Schneider, Gerhard Walther, Karl-Heinz Weber
  • Patent number: 4767759
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms;R.sub.2 is 2-, 3- or 4-pyridyl, phenyl or mono- or di- substituted phenyl, where the substituents are each individually alkoxy of 1 to 2 carbon atoms, fluorine, chlorine, bromine, trifluoromethyl, alkyl or 1 to 4 carbon atoms, hydroxyl or nitro; andR.sub.3 and R.sub.4 are each independently hydrogen or alkyl of 1 to 4 carbon atoms; orR.sub.3 and R.sub.4, together with each other and the nitrogen atom to which they are attached, form an unsubstituted or methyl-substituted, saturated 5- or 6-membered heterocycle which may contain an additional oxygen or nitrogen heteroatom, or form an imidazole ring;where the aminomethyl substituent is attached to the 4- or 5-position or the pyrrolidine ring, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as nootropics and antihypoxics.
    Type: Grant
    Filed: June 26, 1986
    Date of Patent: August 30, 1988
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Gerhard Walther, Claus Schneider, Dieter Hinzen, Franz J. Kuhn, Erich Lehr
  • Patent number: 4762832
    Abstract: The invention relates to new substituted pyrrolidinones of general formula ##STR1## wherein R.sub.1 represents a phenyl group which may be mono- or di-substituted by methyl, methoxy, fluorine, chlorine, bromine or trifluoromethyl, or a pyridyl group;R.sub.2 represents hydrogen or a straight-chained or branched alkyl group with 1-4 carbon atoms;R.sub.3 represents a straight-chained or branched alkyl group with 1-3 carbon atoms, a hydroxyalkyl group with 2-3 carbon atoms, a phenyl group which can be mono- or di-substituted by chlorine, bromine, methyl or methoxy, a cyclohexyl group or a dialkylamino alkyl group, where in each alkyl group can contain from 1-3 carbon atoms;R.sub.4 represents hydrogen or a straight-chained or branched alkyl group with 1-3 carbon atoms; orR.sub.3 and R.sub.
    Type: Grant
    Filed: December 18, 1986
    Date of Patent: August 9, 1988
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Claus Schneider, Gerhard Walther, Dieter Hinzen, Franz J. Kuhn, Erich Lehr, Helmut Ensinger, Wolfgang Troger
  • Patent number: 4755441
    Abstract: A fiber structure-electrode framework of metallized plastic fibers with reinforced edge and with welded-on current-conducting lug, in which the current-conducting lug is provided with one or several steps on the side abutting at the fiber framework. The electrode framework is so connected with the current-conducting lug that the reinforced edge of the electrode framework is located inside of an area whose boundaries lie at the distance of double the lug thickness on both sides of the step. The fiber structure-electrode framework which is compressed in the stepped area reaches its full thickness continuously approximately to the end of the step.
    Type: Grant
    Filed: September 23, 1987
    Date of Patent: July 5, 1988
    Assignee: Deutsche Automobilgesellschaft mbH
    Inventors: Otwin Imhof, Claus Schneider, Willi Kitzhoefer
  • Patent number: 4687719
    Abstract: A metallized synthetic resin fiber electrode structure is described, based on a nonwoven fabric, with a porosity of 85-96% and a fiber thickness of 10-30 .mu.m, determined, respectively, in the nonmetallized condition, wherein the nonmetallized nonwoven fabric is characterized by the following strength properties. The quotient of the flexural stiffness according to DIN 53 362 (cantilever test) and the square of the nonwoven fabric thickness according to DIN 53 855 ranges between 80 and 400 cN. The deformation of a sample stack in the 5th cycle under 200 N in the compression test according to DIN 54 305 amounts to 6-18 mm. The force required to obtain half the achieved deformation amounts to 30-70 N. Polypropylene needle felts are preferred having a metallic coating of 0.1-10 .mu.m, especially 1-6 .mu.m. The electrode structures according to this invention can also be manufactured with larger thicknesses and permit production of rugged electrodes having reproducible properties.
    Type: Grant
    Filed: May 16, 1984
    Date of Patent: August 18, 1987
    Assignee: Deutsche Automobilgesellschaft mbH
    Inventors: Klaus Von Benda, Claus Schneider
  • Patent number: 4686219
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, nitro, amino, cyano, methylsulfonamido, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 3 carbon atoms, (alkyl of 1 to 3 carbon atoms)thio or (alkanoyl of 2 to 4 carbon atoms)amino;R.sub.3 is hydrogen, fluorine, chlorine, bromine or alkyl of 1 to 3 carbon atoms;R.sub.
    Type: Grant
    Filed: February 7, 1986
    Date of Patent: August 11, 1987
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerhard Walther, Claus Schneider, Karl-Heinz Weber, Armin Fugner
  • Patent number: 4670456
    Abstract: The invention relates to new substituted pyrrolidinones of general formula ##STR1## wherein R.sub.1 represents a phenyl group which may be mono- or di-substituted by methyl, methoxy, fluorine, chlorine, bromine or trifluoromethyl, or a pyridyl group;R.sub.2 represents hydrogen or a straight-chained or branched alkyl group with 1-4 carbon atoms;R.sub.3 represents a straight-chained or branched alkyl group with 1-3 carbon atoms, a hydroxyalkyl group with 2-3 carbon atoms, a phenyl group which can be mono- or di-substituted by chlorine, bromine, methyl or methoxy, a cyclohexyl group or a dialkylamino alkyl group, where in each alkyl group can contain from 1-3 carbon atoms;R.sub.4 represents hydrogen or a straight-chained or branched alkyl group with 1-3 carbon atoms; orR.sub.3 and R.sub.
    Type: Grant
    Filed: May 24, 1985
    Date of Patent: June 2, 1987
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Claus Schneider, Gerhard Walther, Dieter Hinzen, Franz J. Kuhn, Erich Lehr, Helmut Ensinger, Wolfgang Troger
  • Patent number: 4666910
    Abstract: Compounds of the formula ##STR1## wherein one of R.sub.1 and R.sub.2 is hydrogen, halogen, methyl, methoxy, amino or nitro and the other is hydrogen; orR.sub.1 and R.sub.2 are both halogen;R.sub.3 is hydrogen, halogen or methyl;R.sub.4 and R.sub.5 are each independently hydrogen or alkyl or 1 to 2 carbon atoms; orR.sub.4 and R.sub.5, together with each other and the nitrogen atom to which they are attached, are pyrrolidino or morpholino; andX is --O--, --NH--, or --S--;and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful anti-depressants.
    Type: Grant
    Filed: August 28, 1984
    Date of Patent: May 19, 1987
    Assignee: Boehringer Ingelheim KG
    Inventors: Claus Schneider, Gerhard Walther, Karl-Heinz Weber, Wolf D. Bechtel, Karin Boke-Kuhn
  • Patent number: 4636510
    Abstract: The invention relates to 4-phenyl-tetrahydro-furano-pyridines of the formulas ##STR1## wherein R.sup.1 to R.sup.5 are variously defined. The compounds of the invention are intended to be used as anti-depressants with, in particular, thymoleptic and central-stimulant properties.
    Type: Grant
    Filed: April 19, 1984
    Date of Patent: January 13, 1987
    Assignee: Boehringer Ingelheim KG
    Inventors: Claus Schneider, Gerhard Walther, Karl-Heinz Weber, Wolf D. Bechtel, Karin Boke-Kuhn
  • Patent number: 4581364
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms; andR.sub.2 is pyridyl, phenyl or mono-, di- or tri-substituted phenyl, where the substituents are alkyl of 1 to 2 carbon atoms, alkoxy of 1 to 2 carbon atoms, fluorine, chlorine, bromine, trifluoromethyl, nitro, benzyloxy or hydroxyl.The compounds are useful as nootropics.
    Type: Grant
    Filed: July 9, 1984
    Date of Patent: April 8, 1986
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Gerhard Walther, Claus Schneider, Dieter Hinzen, Franz J. Kuhn, Erich Lehr
  • Patent number: 4550106
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is amino, acetylamino, hydroxymethyl, methoxymethyl or ##STR2## R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, methoxy, methyl or ethyl;R.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.5 and R.sub.6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocyclic ring where, in the case of a 6-membered ring, a --CH.sub.2 -group in the ring may be replaced by an oxygen atom,and non-toxic, pharmacologically acceptable salts thereof. The compounds as well as their salts are useful as antidepressants.
    Type: Grant
    Filed: July 23, 1984
    Date of Patent: October 29, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Claus Schneider, Gerhard Walther, Karl-Heinz Weber, Wolf D. Bechtel, Karin Boke-Kuhn
  • Patent number: 4503060
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms;R.sub.5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkenyl of 3 to 6 carbon atoms;R.sub.6 is alkyl of 1 to 6 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl, halo-phenyl, lower alkyl-phenyl, or lower alkoxy-phenyl or ##STR2## R.sub.7 and R.sub.8 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy or 1 to 6 carbon atoms;n is an integer from 0 to 4, inclusive;x is --O--, --S--, or --CH.sub.2 --; and the broken line between the 10 and 13b-positions indicates a single or double bond;and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as antiallergics and antithrombotics.
    Type: Grant
    Filed: August 20, 1982
    Date of Patent: March 5, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerhard Walther, Claus Schneider, Karl-Heinz Weber, Armin F/u/ gner
  • Patent number: 4482559
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is amino, acetylamino, hydroxymethyl, methoxymethyl or ##STR2## R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, methoxy, methyl or ethyl;R.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.5 and R.sub.6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocyclic ring where, in the case of a 6-membered ring, a --CH.sub.2 -group in the ring may be replaced by an oxygen atom, and non-toxic, pharmacologically acceptable salts thereof. The compounds as well as their salts are useful as antidepressants.
    Type: Grant
    Filed: February 14, 1983
    Date of Patent: November 13, 1984
    Assignee: Boehringer Ingelheim KG
    Inventors: Claus Schneider, Gerhard Walther, Karl-Heinz Weber, Wolf D. Bechtel, Karin Boke-Kuhn
  • Patent number: 4439281
    Abstract: Electrode structures made from metallized bodies of a fibrous nature, for example from metallized felt, possess the advantage, deriving from their intrinsic stiffness, of requiring no internally fitted supporting structure. It is, however, difficult to attach the current lead-out tabs to an electrode structure of this type, because it is hightly susceptible to mechanical damage at the point of attachment. These difficulties are avoided, according to the present invention, when the edge of the electrode structure is reinforced, to a width of about 0.3 to about 1 cm, by means of an electrodeposited metal coating. If appropriate, the reinforcement of the edge can also be carried out simultaneously with the production, by electrodeposition, of the electrode structure. The current lead out-tab can be attached to the reinforced edge avoiding such difficulties.
    Type: Grant
    Filed: October 21, 1982
    Date of Patent: March 27, 1984
    Assignee: Deutsche Automobilgesellschaft
    Inventors: Claus Schneider, Gabor Benczur-Urmossy
  • Patent number: 4322423
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is chlorine, bromine or alkyl of 1 to 3 carbon atoms;R.sub.2 is hydrogen or, when R.sub.1 is alkyl, chlorine or bromine;R.sub.1 and R.sub.2, together with each other, are straight alkylene of 3 to 4 carbon atoms;R.sub.3 is hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 2 carbon atoms; hydroxyl or trifluoromethyl; andR.sub.4 is hydrogen, straight or branched alkyl of 1 to 4 carbon atoms or phenyl lower alkyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.
    Type: Grant
    Filed: March 27, 1980
    Date of Patent: March 30, 1982
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Claus Schneider, Karl-Heinz Weber, Adolf Langbein, Wolf D. Bechtel, Karin Boke
  • Patent number: 4315938
    Abstract: Compounds of the formula ##STR1## wherein R.sub.2 is hydrogen, chlorine, bromine, formyl, acetyl, alkyl of 1 to 4 carbon atoms, nitro, cyano or --CH.sub.2 --A;whereA is (alkyl of 1 to 2 carbon atoms)-amino; di(alkyl of 1 to 2 carbon atoms)-amino, where one of the alkyl moieties may have a terminal hydroxyl substituent attached thereto; or a 5-, 6- or 7-membered saturated, nitrogen-containing heterocycle which is attached to the methylene group through the nitrogen atom and may have a hydroxyl or hydroxymethyl substituent attached to a ring carbon atom, and the 6-membered heterocycle may contain oxygen as an additional ring heteroatom in the p-position;R.sub.3 is hydrogen, fluorine, chlorine, bromine, methyl or methoxy; andR.sub.4 is hydrogen or alkyl of 1 to 3 carbon atoms;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.
    Type: Grant
    Filed: June 30, 1980
    Date of Patent: February 16, 1982
    Assignee: Boehringer Ingelheim Gmbh
    Inventors: Claus Schneider, Karl-Heinz Weber, Gerhard Walther, Karin Boke, Wolf D. Bechtel
  • Patent number: 4297354
    Abstract: Compounds of the steroisomeric formulas ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each phenyl, substituted phenyl, thienyl or furyl;R.sub.3 is hydrogen or straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; orR.sub.3 and R.sub.4, together with each other and the nitrogen atom to which they are attached, form a piperidino, 4-amino-piperidino, 4-(lower alkylamino)-piperidino, piperazino, 4-(alkyl of 1 to 2 carbon atoms)-piperazino or morpholino radical; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.
    Type: Grant
    Filed: December 15, 1980
    Date of Patent: October 27, 1981
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Karl-Heinz Weber, Claus Schneider, Gerhard Walther, Karl-Heinz Pook, Karin Boke, Wolf D. Bechtel
  • Patent number: 4180573
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, di(lower alkyl)amino-lower alkyl, phenyl, tolyl, methoxy-phenyl, nitro-phenyl, halo-phenyl, pyridyl, pyrimidinyl or --CO--R.sub.4, where R.sub.4 is hydrogen, alkyl or 1 to 17 carbon atoms, alkoxy of 1 to 2 carbon atoms, phenyl, tolyl, methoxy-phenyl, halo-phenyl, nitro-phenyl or pyridyl;R.sub.2 is hydrogen, fluorine, chlorine, or bromine; andR.sub.3 is chlorine, bromine or lower alkyl,and non-toxic, pharmacologically acceptable acid addition salts of certain of these compounds. The compounds as well as the salts are useful as anxiolytics, tranquilizers, sedatives or neuroleptics.
    Type: Grant
    Filed: July 13, 1978
    Date of Patent: December 25, 1979
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Karl-Heinz Weber, Adolf Langbein, Claus Schneider, Erich Lehr, Karin Boke, Franz J. Kuhn