Patents by Inventor Clive Hoggart

Clive Hoggart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210246506
    Abstract: A method of identifying a subject having Kawasaki disease (KD), which includes discriminating the subject from a subject having another condition, for example other infectious and inflammatory conditions, such as those that present similar symptoms to KD. Also provided is a minimal gene signature employed in the method, as well as primers, probes and gene chips for use in the method.
    Type: Application
    Filed: August 5, 2019
    Publication date: August 12, 2021
    Inventors: Jethro HERBERG, Victoria WRIGHT, Michael LEVIN, Clive HOGGART, Myrsini KAFOROU, Jane BURNS
  • Publication number: 20190062812
    Abstract: The invention relates to a method for the diagnosis of TB in a subject, the method comprising (a) providing a sample from said subject, said sample being selected from the group consisting of: blood, serum and plasma; (b) determining the concentration in said sample of the following biomarkers: IL-1ra, IL6, IL-7, IL-8, IL-12p70, FGF-basic, IP-10, and VEGF; (c) converting each biomarker concentration determined in (b) into a decile value; and (d) converting each decile value into a binary presence or absence by comparing the decile values of (c) to the following specific quantile cut off values wherein a decile value matching or exceeding the specific quantile cut-off value is converted into the binary presence of the biomarker, and a decile value lower than the specific quantile cut-off value is converted into the binary absence of the biomarker; wherein detecting the presence of each of said biomarkers indicates that the subject has TB. The invention also relates to uses, kits and devices.
    Type: Application
    Filed: February 3, 2017
    Publication date: February 28, 2019
    Applicants: Medical Research Council, Imperial Innovations Limited
    Inventors: Beate KAMPMANN, Toyin TOGUN, Clive HOGGART
  • Publication number: 20020016699
    Abstract: In many situations it is required to predict if and/or when an event will occur after a trigger. For example, businesses such as banks would like to predict if and when their customers are likely to leave after a particular event such as closing a loan. The business is then able to take action to prevent loss of customers. Customer data including data about customer who have closed a loan and then left a bank for example, is used to create a Bayesian statistical model. A plurality of attributes are available for each customer and the model involves partitioning these attributes into a plurality of partitions. In one embodiment the Bayesian statistical model is a survival analysis type model and in another embodiment the model comprises fitting a Weibull distribution to the data in each of the partitions. The marginal likelihood of the data is calculated and then the method involves mixing over all possible partitions in a Bayesian framework.
    Type: Application
    Filed: May 24, 2001
    Publication date: February 7, 2002
    Inventors: Clive Hoggart, James Griffin