Abstract: A device for occluding a patient's left atrial appendage (LAA) device includes a self-expanding closure disc and an anchor. The self-expanding closure disc has an atrial side, an appendage side, and a peripheral edge configured to engage tissue on both an atrial side and an appendage side of an opening between the left atrium and the left atrial appendage. The self-expanding anchor extends from the appendage side of the self-expanding closure disc, and an annular sealing skirt extends about at least a portion of the appendage side of the self-expanding closure disc. the annular sealing skirt is more compliant than the self-expanding closure disc to seal over the left appendage side of the opening after implantation of the device in the LAA.

Abstract: Endoluminal devices are provided for the treatment of heart failure which include a central body adapted to permit the passage of interatrial blood, at least one anchor attached to the central body adapted to keep the endoluminal device in position within a defect present in the atrial septum of a patient's heart, and at least one control element engaged with the central body in a rotating manner. The rotation of the control element in relation to the central body creates a two-way flow of interatrial blood which allows the reduction of high pressure in the right side and in the left side of the heart.

Abstract: A pumping system (200) for controlling the flow of interatrial blood comprises, housed inside a container (201), a control element (30, 30?, 30?) of the interatrial blood flow. The control element comprises: at least one worm screw (31), the rotation of which creates a two-way flow of interatrial blood; or a pair of counter-rotating propellers (31?); or a pair of membranes (31?) whose deformation creates a two-way flow of interatrial blood; or a flexible structure (31?) whose change in volume within the container (201) creates a two-way flow of interatrial blood.

Abstract: Endoluminal devices are provided for the treatment of heart failure which include a central body adapted to permit the passage of interatrial blood, at least one anchor attached to the central body adapted to keep the endoluminal device in position within a defect present in the atrial septum of a patient's heart, and at least one control element engaged with the central body in a rotating manner. The rotation of the control element in relation to the central body creates a two-way flow of interatrial blood which allows the reduction of high pressure in the right side and in the left side of the heart.