Patents by Inventor Craig S. Atwood

Craig S. Atwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180221419
    Abstract: Methods are described for differentiating stem and post-natal cells into sex hormone-producing cells that can be administered to a patient autologously or allogeneically in order to maintain in balance, or rebalance, their hypothalamic-pituitary-gonadal (HPG) axis.
    Type: Application
    Filed: April 6, 2018
    Publication date: August 9, 2018
    Inventors: Craig S. Atwood, Sivan Vidakkadath Meethal
  • Publication number: 20170016072
    Abstract: Disclosed are methods for diagnosis or prognosis of Alzheimer's disease in a patient. The methods may include assessing whether a patient has Alzheimer's disease or assessing a patient's risk for developing Alzheimer's disease. The methods typically include determining, either directly or indirectly, whether the patient has mutations, such as single nucleotide polymorphisms, in a plurality of genes that encode gene products that function in steroid biosynthesis.
    Type: Application
    Filed: September 29, 2016
    Publication date: January 19, 2017
    Inventor: Craig S. Atwood
  • Publication number: 20150359822
    Abstract: A hypothalamic-pituitary-gonadal (HPG) axis of a patient in need thereof is rebalanced by administering a therapeutically effective amount of at least one donor cell.
    Type: Application
    Filed: May 21, 2015
    Publication date: December 17, 2015
    Inventor: Craig S. Atwood
  • Patent number: 8906877
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in tissue engineering as well as identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility. Examples of tissue engineering include techniques that allow for the generation of biological substitutes that restore, maintain, or improve tissue function or a whole organ.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: December 9, 2014
    Assignee: GenRemedy, LLC
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Publication number: 20140206012
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in tissue engineering as well as identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility. Examples of tissue engineering include techniques that allow for the generation of biological substitutes that restore, maintain, or improve tissue function or a whole organ.
    Type: Application
    Filed: April 1, 2014
    Publication date: July 24, 2014
    Applicant: GenRemedy LLC
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Patent number: 8716466
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: May 6, 2014
    Assignee: Genremedy LLC
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Patent number: 8329891
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: December 11, 2012
    Assignee: Genremedy LLC
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Publication number: 20120190588
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility.
    Type: Application
    Filed: February 6, 2012
    Publication date: July 26, 2012
    Applicant: GenRemedy LLC
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Patent number: 8110355
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: February 7, 2012
    Assignee: GenRemedy, LLC
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Publication number: 20120003649
    Abstract: Disclosed are methods for diagnosis or prognosis of Alzheimer's disease in a patient. The methods may include assessing whether a patient has Alzheimer's disease or assessing a patient's risk for developing Alzheimer's disease. The methods typically include determining, either directly or indirectly, whether the patient has mutations, such as single nucleotide polymorphisms, in a plurality of genes that encode gene products that function in steroid biosynthesis.
    Type: Application
    Filed: August 8, 2011
    Publication date: January 5, 2012
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Craig S. Atwood
  • Publication number: 20100273163
    Abstract: Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility.
    Type: Application
    Filed: February 22, 2010
    Publication date: October 28, 2010
    Inventors: Craig S. Atwood, Sivan Vadakkadath Meethal
  • Publication number: 20100035266
    Abstract: Disclosed are methods for diagnosis or prognosis of Alzheimer's disease in a patient. The methods may include assessing whether a patient has Alzheimer's disease or assessing a patient's risk for developing Alzheimer's disease. The methods typically include determining, either directly or indirectly, whether the patient has mutations, such as single nucleotide polymorphisms, in a plurality of genes that encode gene products that function in steroid biosynthesis.
    Type: Application
    Filed: July 28, 2009
    Publication date: February 11, 2010
    Applicant: Wisconsin Alumni Research Foundation
    Inventor: Craig S. Atwood
  • Patent number: 7045531
    Abstract: The invention relates to the identification of pharmacological agents to be used in the treatment of Alzheimer's disease and related pathological conditions. Methods and compositions for treatment of conditions caused by amyloidosis, A?-mediated ROS formation, or both, such as Alzheimer's disease, are disclosed.
    Type: Grant
    Filed: March 11, 1998
    Date of Patent: May 16, 2006
    Assignee: The General Hospital Corporation
    Inventors: Ashley I. Bush, Xudong Huang, Craig S. Atwood, Rudolph E. Tanzi
  • Patent number: 6638711
    Abstract: The invention relates to methods for identifying candidate pharmacological agents to be used in the treatment and/or prevention of Alzheimer's disease and/or related pathological conditions.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: October 28, 2003
    Assignee: The General Hospital Corporation
    Inventors: Ashley I. Bush, Xudong Huang, Craig S. Atwood, Rudolph E. Tanzi
  • Publication number: 20020082273
    Abstract: The invention relates to the identification of pharmacological agents to be used in the treatment of Alzheimer's disease and related pathological conditions and compositions for treatment of conditions caused by amyloidosis, A&bgr;-mediated formation of ROS, or both, such as Alzheimer's disease, are disclosed.
    Type: Application
    Filed: September 21, 2001
    Publication date: June 27, 2002
    Inventors: Ashley I. Bush, Xudong Huang, Craig S. Atwood, Rudolph E. Tanzi
  • Patent number: 6323218
    Abstract: The invention relates to the identification of pharmacological agents to be used in the treatment of Alzheimer's disease and related pathological conditions and compositions for treatment of conditions caused by amyloidosis, A&bgr;-mediated formation of ROS, or both, such as Alzheimer's disease.
    Type: Grant
    Filed: March 11, 1998
    Date of Patent: November 27, 2001
    Assignee: The General Hospital Corporation
    Inventors: Ashley I. Bush, Xudong Huang, Craig S. Atwood, Rudolph E. Tanzi