Patents by Inventor Dan-Paul Hartmann

Dan-Paul Hartmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210038565
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: October 16, 2020
    Publication date: February 11, 2021
    Applicant: GEORGETOWN UNIVERSITY
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Publication number: 20190269648
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: October 5, 2018
    Publication date: September 5, 2019
    Applicant: Georgetown University
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Publication number: 20170246145
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: October 13, 2016
    Publication date: August 31, 2017
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Publication number: 20150196530
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: January 26, 2015
    Publication date: July 16, 2015
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Patent number: 8940787
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: January 27, 2015
    Assignee: Georgetown University
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Patent number: 8779312
    Abstract: The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as a multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: July 15, 2014
    Assignees: United States of America/NIH, 20/20 Genesystems, Inc.
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Michael R. Emmert-Buck
  • Publication number: 20130296411
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: February 26, 2013
    Publication date: November 7, 2013
    Inventors: Richard SCHLEGEL, Dan-Paul HARTMANN, Astrid BAEGE
  • Patent number: 8394849
    Abstract: In certain aspects, the invention relates to methods of treating proliferative oropharyngeal cancer, laryngeal cancer and esophageal cancer by administering artemisinin-related compounds.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: March 12, 2013
    Assignee: Georgetown University
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Publication number: 20120010278
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: July 11, 2011
    Publication date: January 12, 2012
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Patent number: 7989491
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infections by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: August 2, 2011
    Assignee: Georgetown University
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Patent number: 7838222
    Abstract: The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as a multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: November 23, 2010
    Assignees: United States of America/ NIH, 20/20 Genesystems, Inc.
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Michael R. Emmert-Buck
  • Publication number: 20100137160
    Abstract: The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as a multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
    Type: Application
    Filed: November 25, 2009
    Publication date: June 3, 2010
    Inventors: Vladimir KNEZEVIC, Dan-Paul Hartmann, Michael R. Emmert-Buck
  • Publication number: 20070142459
    Abstract: In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infections by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
    Type: Application
    Filed: February 12, 2004
    Publication date: June 21, 2007
    Inventors: Richard Schlegel, Dan-Paul Hartmann, Astrid Baege
  • Publication number: 20060211011
    Abstract: The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as a multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
    Type: Application
    Filed: March 22, 2006
    Publication date: September 21, 2006
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Michael Emmert-Buck
  • Patent number: 6969615
    Abstract: The present disclosure is directed to devices, arrays, kits and methods for detecting biomolecules in a tissue section (such as a fresh or archival sample, tissue microarray, or cells harvested by an LCM procedure) or other substantially two-dimensional sample (such as an electrophoretic gel or cDNA microarray) by creating “carbon copies” of the biomolecules eluted from the sample and visualizing the biomolecules on the copies using one or more detector molecules (e.g., antibodies or DNA probes) having specific affinity for the biomolecules of interest. Specific methods are provided for identifying the pattern of biomolecules (e.g., proteins and nucleic acids) in the samples. Other specific methods are provided for the identification and analysis of proteins and other biological molecules produced by cells and/or tissue, especially human cells and/or tissue.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: November 29, 2005
    Assignees: 20/20 GeneSystems, Inc., The United States of America as represented by the Department of Health and Human Services
    Inventors: Vladimir Knezevic, Michael R. Emmert-Buck, Galina Baibakova, Dan-Paul Hartmann, Stephen M. Hewitt, Capre Denise Mitchell, Kevin Gardner
  • Publication number: 20050255473
    Abstract: The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as a multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
    Type: Application
    Filed: August 1, 2003
    Publication date: November 17, 2005
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Michael Emmert-Buck
  • Publication number: 20050238535
    Abstract: Provided herein are methods for preliminary analysis of suspect samples, which can be used in triaging possible contaminated sites (e.g., sites contaminated or thought to be contaminated by biowarfare agents). In some embodiments, the methods involve testing for the presence of protein in the suspect sample; optionally, the sample can also be tested for the presence of sugar, and/or for pH determination. Specific embodiment methods are carried out in tubes or other reaction vessels, others are carried out in a pad format, and still others are carried out in a test strip format. Kits for carrying out the described methods are also provided.
    Type: Application
    Filed: January 27, 2005
    Publication date: October 27, 2005
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Jonathan Cohen, Elizabeth Marcus, Gerard Troy
  • Patent number: 6958242
    Abstract: Provided herein are methods for preliminary analysis of suspect samples, which can be used in triaging possible contaminated sites (e.g., sites contaminated or thought to be contaminated by biowarfare agents). In some embodiments, the methods involve testing for the presence of protein in the suspect sample; optionally, the sample can also be tested for the presence of sugar, and/or for pH determination. Specific embodiment methods are carried out in tubes or other reaction vessels, others are carried out in a pad format, and still others are carried out in a test strip format. Kits for carrying out the described methods are also provided.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: October 25, 2005
    Assignee: 20/20/GeneSystems, Inc.
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Jonathan Cohen, Elizabeth Marcus
  • Publication number: 20050148090
    Abstract: Provided herein are methods for preliminary analysis of suspect samples, which can be used in triaging possible contaminated sites (e.g., sites contaminated or thought to be contaminated by biowarfare agents). In some embodiments, the methods involve testing for the presence of protein in the suspect sample; optionally, the sample can also be tested for the presence of sugar, and/or for pH determination. Specific embodiment methods are carried out in tubes or other reaction vessels, others are carried out in a pad format, and still others are carried out in a test strip format. Kits for carrying out the described methods are also provided.
    Type: Application
    Filed: May 14, 2004
    Publication date: July 7, 2005
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Jonathan Cohen, Elizabeth Marcus
  • Patent number: 6770485
    Abstract: Provided herein are methods for preliminary analysis of suspect samples, which can be used in triaging possible contaminated sites (e.g., sites contaminated or thought to be contaminated by biowarfare agents). In some embodiments, the methods involve testing for the presence of protein in the suspect sample; optionally, the sample can also be tested for the presence of sugar, and/or for pH determination. Specific embodiment methods are carried out in tubes or other reaction vessels, others are carried out in a pad format, and still others are carried out in a test strip format. Kits for carrying out the described methods are also provided.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: August 3, 2004
    Assignee: 20/20 GeneSystems, Inc.
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Jonathan Cohen, Elizabeth Marcus