Patents by Inventor Dan Y. Wu

Dan Y. Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Allele specific polymerase chain reaction
    Patent number: 5639611
    Abstract: A rapid, non-radioactive approach to the diagnosis of sickle cell anemia is described based on an allele specific polymerase chain reaction (ASPCR) in which the 3'-terminal nucleotide of one of the primers of the primer set forms a match with one allele and a mismatch with the other allele. This method allows the direct detection of the normal or the sickle cell .beta.-globin allele in genomic DNA without the additional steps of probe hybridization, ligation or restriction enzyme cleavage.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: June 17, 1997
    Assignee: City of Hope
    Inventors: R. Bruce Wallace, Bijay K. Pal, Luis A. Ugozzoli, Dan Y. Wu