Abstract: An aspect of the present disclosure is a system that includes a thermal valve having a first position and a second position, a heat transfer fluid, and an energy converter where, when in the first position, the thermal valve prevents the transfer of heat from the heat transfer fluid to the energy converter, and when in the second position, the thermal valve allows the transfer of heat from the heat transfer fluid to the energy converter, such that at least a portion of the heat transferred is converted to electricity by the energy converter.

Abstract: A motion compensation system includes a plurality of RF transmitters, a plurality of direction of arrival sensors, and a positioning table which together are usable to compensate for intrafraction motion of a patient during a medical procedure. The positioning table may be a secondary table arranged next to or above a primary table such as a radiotherapy couch, allowing for repositioning of part of patient such as the head and neck relative to a remainder of the body. The motion compensation system employs a direction of arrival sensor that includes rotating antenna elements in a configuration that improves the ease and accuracy of signal processing and analysis to identify the position of an RF transmitter affixed to a patient. The repositioning table has six degrees of freedom and is safe for use in imaging and radiation intensive environments.

Abstract: A monorail vehicle includes a chassis supporting a vehicle body, that includes a passenger floor and at least one side wall, and an electrical motor supported by the chassis. A drive wheel is coupled to a rotor of the electric motor with a rotation axis of the drive wheel substantially coaxial with an axis of the rotor. Portions of the drive wheel and the electric motor are positioned on both sides of an imaginary plane extension of the passenger floor. The drive wheel and the electric motor are covered by a shell that is integral to one side of the vehicle body and which defines a space between the other side of the vehicle body.

Abstract: The present invention concerns a method for identifying and using a biomarker, or creating a proteome profile, indicative of a reduced response to a drug in a patient involving a thermal shift assay on a sample. The method comprises the steps of a) heating a sample from a patient b) separating soluble from insoluble protein, c) analysing either or both the soluble and insoluble protein fractions of step b) to determine the melting temperature.

Abstract: The present invention refers to a process for preparing an animal brain extract. It also refers to the brain extract obtainable according to said process and to the use thereof as a medicine, in particular for the prevention and/or treatment of neurodegenerative diseases and disorders of the central nervous system. It also refers to compositions comprising this extract and to its use for preparing these compositions.

Abstract: A monorail vehicle includes a chassis supporting a vehicle body that includes a passenger floor, a first side wall, and a second side wall and first and second propulsion systems. Each propulsion system includes an electric motor and a drive wheel coupled to a rotor of the electric motor. Each electric motor and the drive wheel coupled to the rotor of the electric motor are positioned on both sides of an imaginary plane extension of the passenger floor. First and second shells cover portions of the first and second propulsion system. The first shell is positioned proximate to the first side wall and defines a first space between the second side wall. The second shell is positioned proximate to the second side wall and defines a second space between the first side wall.

Abstract: A monorail vehicle includes a chassis supporting a vehicle body, that includes a passenger floor and at least one side wall, and an electrical motor supported by the chassis. A drive wheel is coupled to a rotor of the electric motor with a rotation axis of the drive wheel substantially coaxial with an axis of the rotor. Portions of the drive wheel and the electric motor are positioned on both sides of an imaginary plane extension of the passenger floor. The drive wheel and the electric motor are covered by a shell that is integral to one side of the vehicle body and which defines a space between the other side of the vehicle body.

Abstract: A vehicle includes an engine, a manual transmission, and a clutch that selectively couples the engine to the transmission. The clutch includes a disk biased to engage a flywheel of the engine, a first actuator that disengages the disk in response to depression of a clutch pedal, and a second actuator that disengages the disk in response to an electric signal from a vehicle controller.

Abstract: A vehicle includes an engine, a manual transmission, and a clutch that selectively couples the engine to the transmission. The clutch includes a disk biased to engage a flywheel of the engine, a first actuator that disengages the disk in response to depression of a clutch pedal, and a second actuator that disengages the disk in response to an electric signal from a vehicle controller.

Abstract: A web-based software application accessible by subscribers via the internet at: http://cstore.saltwaretax.com, which allows convenience store and similar retail store owners to calculate Texas sales and use taxes by entering their purchases manually or by importing records electronically. The application connects to a database named “Cstore” which stores taxability decisions for convenience store products and expenses and is used by the application to calculate the sales tax payable. The subscriber may also upload digital images of transaction invoices to be stored electronically for future reference.

Abstract: A process of making a tack-free gel is disclosed comprising the steps of providing a mold defining a mold cavity, the mold cavity comprising a plastic material; pouring or injecting a molten gel having a high molding temperature into the mold cavity; and forming the tack-free gel as a thin layer of plastic of the mold cavity is melted over the gel. The forming step further comprises cooling the gel from the molten state to a solidified state. The melting temperature of the plastic material is lower than the molding temperature of the gel; and the higher the temperature differential, the greater the melting of the plastic material and the thicker the layer of the plastic material on the surface of the gel. The mold may be formed of low-density polyethylene (LDPE).

Abstract: Embodiments of an isolator are provided, as are embodiments of a spacecraft isolation system employing a number of three parameter isolators. In one embodiment, the isolator includes a damper assembly and a thermal compensator external to the damper assembly. The damper assembly includes, in turn, a damper housing and a first hydraulic chamber, which is located within the damper housing and which is configured to contain a damping fluid. The thermal compensator includes a thermal compensator chamber, which is fluidly coupled to the first hydraulic chamber and which is configured to exchange damping fluid therewith during operation of the isolator. A thermal compensator bellows bounds an inner circumference of the thermal compensator chamber such that the bellows is externally pressurized when the first hydraulic chamber and the thermal compensator chamber are filled with the damping fluid.

Abstract: An aspect of the present disclosure is a system that includes a thermal valve having a first position and a second position, a heat transfer fluid, and an energy converter where, when in the first position, the thermal valve prevents the transfer of heat from the heat transfer fluid to the energy converter, and when in the second position, the thermal valve allows the transfer of heat from the heat transfer fluid to the energy converter, such that at least a portion of the heat transferred is converted to electricity by the energy converter.

Abstract: The present invention concerns a method of determining whether a non-purified sample contains a target protein bound to a ligand of interest comprising the steps of a) exposing the non-purified sample to a temperature which is capable of causing or enhancing precipitation of the unbound target protein to a greater extent than it is capable of causing or enhancing precipitation of the target protein bound to the ligand; and b) analyzing said sample for the presence of soluble or native target protein using two or more affinity reagents capable of binding to said soluble or native target protein with a higher affinity than to an unfolded and/or insoluble form of said target protein. The invention particularly concerns the use of two affinity reagents (e.g. antibodies) which are capable of distinguishing between soluble or native, and unfolded and/or insoluble forms of a target protein and whose detection e.g. by FRET based technology, allows the performance of the method without a separation step.

Abstract: Embodiments of an isolator are provided, as are embodiments of a spacecraft isolation system employing a number of three parameter isolators. In one embodiment, the isolator includes an externally-pressurized damper assembly and a thermal compensator, which is located external to the externally-pressurized damper assembly. The damper assembly includes, in turn, a damper assembly housing and a first hydraulic chamber configured to be filled with a damping fluid. The first hydraulic chamber is located within the damper assembly housing and is fluidly coupled to the thermal compensator. A first bellows is disposed within the damper assembly housing and bounds an inner circumference of the first hydraulic chamber such that the first bellows is externally pressurized when the first hydraulic chamber is filled with the damping fluid.

Abstract: A pharmaceutical composition for a sustained release of peptide therapeutics, in particular for a sustained release compatible with therapeutic treatments of at least two months. In an embodiment, the composition comprises lanreotide as an active agent, a hydrosoluble co-solvent, and water with the pH of the composition being from 4.0 to 7.5.

Abstract: A workbench and an assistance method for manufacturing or checking electrical wiring harnesses. The workbench comprises: an assembly board; image projection devices on the assembly board; optical sensors arranged on the assembly board to provide information about its position; cameras arranged to capture gestures of the technician in charge of the workbench; a computer with a set of computer programs adapted to provide, through the image projection devices images in 1:1 scale of templates of the electrical wiring harness being manufactured or checked projected onto the assembly board and, superimposed on them, complementary images of aid requested by the technician, acting on virtual menus and/or buttons projected onto the assembly board.

Abstract: A method of manufacturing a cooled turbine blade for use in a gas turbine engine. The method includes forming an inner blade pattern, the inner blade pattern including an inner spar and a plurality of inner spar cooling fins. The method also includes forming an inner blade core, removing the inner blade pattern from the inner blade core, forming an outer blade pattern, forming a casting shell, removing the outer blade pattern from the casting shell, and casting the cooled turbine blade in the casting shell. The method also includes removing the casting shell from the cast cooled turbine blade, and removing the inner blade core from the cast cooled turbine blade.

Abstract: The present invention pertains to the field of genomics and nanotechnology, specifically to the in vivo gene expression technologies and their application in gene therapy. It consists of the performance of the NTS-polyplex nanocomplex, which can carry nucleic acids to the neurons, involving neurotrophic therapy to treat neurodegenerative diseases. In particular, the present invention addresses the treatment of Parkinson's disease by the regulated expression of the BDNF neurotrophin.

Abstract: A monorail vehicle includes a chassis supporting a vehicle body, that includes a passenger floor and at least one side wall, and an electrical motor supported by the chassis. A drive wheel is coupled to a rotor of the electric motor with a rotation axis of the drive wheel substantially coaxial with an axis of the rotor. Portions of the drive wheel and the electric motor are positioned on both sides of an imaginary plane extension of the passenger floor.