Abstract: A mechanism for adjusting occlusion of a roller pump is described, wherein the mechanism is provided with: an elongated rod member oriented on a central axis of a pump head of the roller pump; and a drive member attached to the elongated rod member so as to move along the elongated rod member between a first position and a second position, wherein the drive member is connected to each roller block of a pump rotor of the pump head so that movement of the drive member by constant increments along the elongated rod member causes non-uniform and/or non-linear incremental movement of each roller block in a direction radial to the central axis of the pump head.

Abstract: Disclosed herein are heart pumps that can include a catheter body and an impeller coupled with a distal end of the catheter body. The impeller can include a tip that is resealable or that includes a resealable member. The heart pump can also include a diffuser disposed between the distal end of the catheter body and the impeller, wherein the diffuser includes a flow directing surface.

Abstract: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g. optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyses, and/or measuring the return interval from a failed ATP attempt; the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.

Abstract: Apparatus, systems, and methods are provided for optimizing intracardiac filling pressures and cardiac output in patients with heart failure, conduction disease, and atrial fibrillation. The system is able to adjust and optimize intracardiac filling pressures and cardiac output by adjusting heart rate and the effective amount of total body blood volume. The device includes an adjustable member that may create a mean pressure differential in order to manifest an effective “mechanical diuresis” by sequestering extraneous blood volume to the high-capacitance of the venous vasculature. The system is therefore designed to reduce intracardiac filling pressures while maintaining or even increasing cardiac output.

Abstract: Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one component designed to cause dyssynchrony of the right ventricle, and a controller configured for adjusting the function of the at least one component based at least in part on sensor data from the at least one sensor.

Abstract: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g. optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyses, and/or measuring the return interval from a failed ATP attempt; the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.

Abstract: Disclosed herein are heart pumps that can include a catheter body and an impeller coupled with a distal end of the catheter body. The impeller can include a tip that is resealable or that includes a resealable member. The heart pump can also include a diffuser disposed between the distal end of the catheter body and the impeller, wherein the diffuser includes a flow directing surface.

Abstract: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g., for optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyses, and/or measuring the return interval from a failed ATP attempt, the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.

Abstract: A biasing circuit includes a differential communication line comprising a first signal line and a second signal line. The biasing circuit further includes a first current source coupled between a power supply and the first signal line. The biasing circuit further includes a first high-precision voltage reference coupled to the first current source, wherein the first high-precision voltage reference outputs a reference voltage that drives a current produced by the first current source. The biasing circuit further includes a second current source coupled to the second signal line and a system ground, wherein the second current source is driven by a voltage supplied by the power supply.

Abstract: Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one adjustable component designed to cause blood to flow in a direction opposite to the normal direction (regurgitation) within the patient's heart; and a controller configured for adjusting the function of the at least one adjustable component based at least in part on sensor data from the at least one sensor.

Abstract: The present disclosure relates to a hydraulic mining shovel. The shovel may comprise a main frame, a power module and a counterweight module. The shovel may further comprise a first exhaust aftertreatment module and a second exhaust aftertreatment module, each being mounted onto the counterweight module and each including a reductant tank and pump unit and a selective catalytic reduction unit. The first exhaust aftertreatment module and the second exhaust aftertreatment module may be configured and arranged substantially mirror-symmetrically at opposing sides of the counterweight module with respect to a central longitudinal axis of the main frame.

Abstract: A biasing circuit includes a differential communication line comprising a first signal line and a second signal line. The biasing circuit further includes a first current source coupled between a power supply and the first signal line. The biasing circuit further includes a first high-precision voltage reference coupled to the first current source, wherein the first high-precision voltage reference outputs a reference voltage that drives a current produced by the first current source. The biasing circuit further includes a second current source coupled to the second signal line and a system ground, wherein the second current source is driven by a voltage supplied by the power supply.

Abstract: The invention relates to a rail attachment system (1) for attaching a rail (2) to a concrete support slab (3a) or a concrete sleeper (3b) or to a steel structure comprising an intermediate plate (4), a rail attachment plate (5) with angle guide plates (6, 6b) arranged thereon, at least two first tensioning clamps (7a) for clamping the rail foot (2a) to the rail attachment plate (5) as well as screws (9) and/or ankle bolts (10) and at least two second tensioning clamps for screwing the rail attachment system (1) to the underlying surface, characterized in that an elastic intermediate layer (8) is arranged between the rail (2) and the rail attachment plate (5), and the intermediate plate (4) is composed of a highly elastic material and/or comprises a steel plate (4), at least two second tensioning clamps (7b) for clamping the rail attachment plate (5) to the substructure, preferably via the intermediate plate (4), wherein the first and second tensioning clamps (7a, 7b) are embodied in a highly elastic fashion w