Patents by Inventor Daniel Bedau

Daniel Bedau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230176032
    Abstract: Disclosed herein are devices, systems, and methods for controlling a translocation speed of a molecule through a nanopore. In some embodiments, a speed-control device comprises at least one fluid-retaining surface, a fluid region, a field-responsive fluid coupled to the fluid-retaining surface and situated in the fluid region. In some embodiments, a system comprises the nanopore, the speed-control device, and a field generator for generating a magnetic or electric field across the fluid region. The viscosity of the field-responsive fluid is dependent on a magnitude of the magnetic or electric field across the fluid region and can be controlled by changing a magnitude of the magnetic or electric field across the fluid region.
    Type: Application
    Filed: December 8, 2021
    Publication date: June 8, 2023
    Applicant: Western Digital Technologies, Inc.
    Inventors: Daniel BEDAU, Justin P. KINNEY
  • Publication number: 20230176033
    Abstract: Disclosed herein are devices, systems, and methods for controlling the movement of at least one molecule in a first fluid having a first viscosity. The system includes a fluid region defined by at least one fluid-retaining surface, a field-responsive fluid situated in the fluid region, and a field generator for generating a magnetic or electric field across the fluid region. The fluid region is traversable by the at least one molecule. In response to a magnitude of the magnetic or electric field across the fluid region exceeding a threshold magnitude, a viscosity of the field-responsive fluid is greater than the first viscosity.
    Type: Application
    Filed: December 8, 2021
    Publication date: June 8, 2023
    Applicant: Western Digital Technologies, Inc.
    Inventors: Daniel BEDAU, Justin P. KINNEY
  • Patent number: 11609208
    Abstract: Disclosed herein are detection devices, systems, and methods that use magnetic nanoparticles (MNPs) to allow molecules to be identified. Embodiments of this disclosure include magnetic sensors (e.g., magnetoresistive sensors) that can be used to detect temperature-dependent magnetic fields (or changes in magnetic fields) emitted by MNPs, and, specifically to distinguish between the presence and absence of magnetic fields emitted, or not emitted, by MNPs at different temperatures selected to take advantage of knowledge of how the MNPs' magnetic properties change with temperature. Embodiments disclosed herein may be used for nucleic acid sequencing, such as deoxyribonucleic acid (DNA) sequencing.
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: March 21, 2023
    Assignee: Western Digital Technologies, Inc.
    Inventors: Patrick Braganca, Daniel Bedau
  • Patent number: 11579217
    Abstract: Devices and methods for molecule detection using such devices are disclosed herein. A molecule detection device comprises at least one fluidic channel configured to receive molecules to be detected, a sensor comprising a spin torque oscillator (STO) and encapsulated by a material separating the sensor from the at least one fluidic channel, and detection circuitry coupled to the sensor. At least some of the molecules to be detected are labeled by magnetic nanoparticles (HNPs). A surface of the material provides binding sites for the molecules to be detected. The detection circuitry is configured to detect a frequency or frequency noise of a radio-frequency (RF) signal generated by the STO in response to presence or absence of at least one MNP coupled to one or more binding sites associated with the sensor.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: February 14, 2023
    Assignee: Western Digital Technologies, Inc.
    Inventors: Patrick Braganca, Daniel Bedau
  • Publication number: 20220376711
    Abstract: Example systems, read channels, and methods provide bit value detection from an encoded data signal using a neural network soft information detector. The neural network detector determines a set of probabilities for possible states of a data symbol from the encoded data signal. A soft output detector uses the set of probabilities for possible states of the data symbol to determine a set of bit probabilities that are iteratively exchanged as extrinsic information with an iterative decoder for making decoding decisions. The iterative decoder outputs decoded bit values for a data unit that includes the data symbol.
    Type: Application
    Filed: September 21, 2021
    Publication date: November 24, 2022
    Inventors: Iouri Oboukhov, Daniel Bedau, Richard Galbraith, Niranjay Ravindran, Weldon Hanson, Pradhan Bellam
  • Publication number: 20220252587
    Abstract: Disclosed herein are methods of using detection devices. A detection device comprises a fluidic channel configured to receive a plurality of molecules to be detected, a plurality of temperature sensors, and an insulating material encapsulating the plurality of temperature sensors and providing a barrier between the plurality of temperature sensors and contents of the fluidic channel. A surface of the insulating material within the fluidic channel provides a plurality of sites for binding the plurality of molecules to be detected. Each of the plurality of temperature sensors is configured to detect, in the presence of an alternating magnetic field, a temperature change indicating presence or absence of one or more magnetic nanoparticles (MNPs) coupled to at least one of the plurality of molecules to be detected at a respective subset of the plurality of sites.
    Type: Application
    Filed: May 2, 2022
    Publication date: August 11, 2022
    Applicant: Western Digital Technologies, Inc.
    Inventors: Patrick BRAGANCA, Daniel BEDAU
  • Patent number: 11355188
    Abstract: An apparatus is provided that includes a plurality of data arrays each comprising first memory cells, a plurality of read reference arrays each comprising second memory cells, a plurality of write reference arrays each comprising third memory cells, an access block comprising a memory cell from each of the plurality of data arrays, each of the plurality of read reference arrays, and each of the plurality of write reference arrays, and a memory controller. The memory controller is configured to determine a read threshold voltage to compensate a drift of a threshold voltage of the first memory cells, wherein the read threshold voltage is determined based on threshold voltages of a plurality of second memory cells, and a read offset voltage to compensate an offset voltage of the first memory cells, wherein the read offset voltage is determined based on offset voltages of a plurality of second memory cells.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: June 7, 2022
    Assignee: SanDisk Technologies LLC
    Inventors: Michael K. Grobis, Daniel Bedau
  • Patent number: 11327073
    Abstract: Disclosed herein are detection devices, systems including such detection devices, and methods of using such detection devices. A detection device comprises a fluidic channel configured to receive a plurality of molecules to be detected, a plurality of temperature sensors, and an insulating material encapsulating the plurality of temperature sensors and providing a barrier between the plurality of temperature sensors and contents of the fluidic channel. A surface of the insulating material within the fluidic channel provides a plurality of sites for binding the plurality of molecules to be detected. Each of the plurality of temperature sensors is configured to detect, in the presence of an alternating magnetic field, a temperature change indicating presence or absence of one or more magnetic nanoparticles (MNPs) coupled to at least one of the plurality of molecules to be detected at a respective subset of the plurality of sites.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: May 10, 2022
    Assignee: Western Digital Technologies, Inc.
    Inventors: Patrick Braganca, Daniel Bedau
  • Publication number: 20220090173
    Abstract: Disclosed herein are improved methods and systems for sequencing nucleic acid that exploit the temperature-dependence of the emitted intensity of fluorescent dyes. The temperature of the sequencing reaction is adjusted during each sequencing cycle, and the emission, or lack of emission, of light meeting or exceeding a threshold by the fluorescent dyes at different temperatures, or within different temperature ranges, is used to detect the fluorescent labels of the incorporated dNTPs and thereby sequence the nucleic acid. The disclosed methods enable a determination of the dNTP incorporated at any given site with a reasonable number of chemistry steps without the complex optics necessary for prior-art systems.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Applicant: Western Digital Technologies, Inc.
    Inventors: Patrick BRAGANCA, Daniel BEDAU
  • Patent number: 11271009
    Abstract: A ferroelectric memory device contains a two-dimensional semiconductor material layer having a band gap of at least 1.1 eV and at least one of a thickness of 1 to 5 monolayers of atoms of the semiconductor material or includes a two-dimensional charge carrier gas layer, a source contact contacting a first portion of the two-dimensional semiconductor material layer, a drain contact contacting a second portion of the two-dimensional semiconductor material layer, a ferroelectric memory element located between the source and drain contacts and adjacent to a first surface of the two-dimensional semiconductor material layer, and a conductive gate electrode located adjacent to the ferroelectric memory element.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: March 8, 2022
    Assignee: SANDISK TECHNOLOGIES LLC
    Inventors: Alan Kalitsov, Derek Stewart, Daniel Bedau, Gerardo Bertero
  • Publication number: 20210406007
    Abstract: In one embodiments, a method is provided. The method includes determining whether a set of algorithmic operations can be represented using an algebraic formulation. The method also includes generating a sequence of idempotent semiring operations based on the set of algorithmic operations in response to determining that the set of algorithmic operations can be represented using the algebraic formulation. The sequence of idempotent semiring operations are part of an algebraic idempotent semiring, represent the algebraic formulation, and comprise one or more of an associative, commutative pick operation that forms an abelian monoid and an associative tally operation that forms a monoid and distributes over the pick operation. The method also includes generating a sequence of microcode instructions based on the sequence of idempotent semiring operations, wherein the sequence of microcode instructions carries out the sequence of idempotent semiring operations.
    Type: Application
    Filed: June 30, 2020
    Publication date: December 30, 2021
    Inventor: Daniel BEDAU
  • Publication number: 20210406009
    Abstract: In one embodiments, a method is provided. The method includes determining whether a set of algorithmic operations can be represented using an algebraic formulation. The method also includes generating a sequence of idempotent semiring operations based on the set of algorithmic operations in response to determining that the set of algorithmic operations can be represented using the algebraic formulation. The sequence of idempotent semiring operations are part of an algebraic idempotent semiring, represent the algebraic formulation, and comprise one or more of an associative, commutative pick operation that forms an abelian monoid and an associative tally operation that forms a monoid and distributes over the pick operation. The method also includes generating a sequence of microcode instructions based on the sequence of idempotent semiring operations, wherein the sequence of microcode instructions carries out the sequence of idempotent semiring operations.
    Type: Application
    Filed: June 30, 2020
    Publication date: December 30, 2021
    Inventor: Daniel BEDAU
  • Patent number: 11208682
    Abstract: Disclosed herein are improved methods and systems for sequencing nucleic acid that exploit the temperature-dependence of the emitted intensity of fluorescent dyes. The temperature of the sequencing reaction is adjusted during each sequencing cycle, and the emission, or lack of emission, of light meeting or exceeding a threshold by the fluorescent dyes at different temperatures, or within different temperature ranges, is used to detect the fluorescent labels of the incorporated dNTPs and thereby sequence the nucleic acid. The disclosed methods enable a determination of the dNTP incorporated at any given site with a reasonable number of chemistry steps without the complex optics necessary for prior-art systems.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: December 28, 2021
    Assignee: Western Digital Technologies, Inc.
    Inventors: Patrick Braganca, Daniel Bedau
  • Publication number: 20210396820
    Abstract: A method of sensing molecules using a detection device, the detection device comprising a plurality of magnetoresistive (MR) sensors and at least one fluidic channel, comprising adding a plurality of molecules to be detected to the at least one fluidic channel, wherein at least some of the plurality of molecules to be detected are coupled to respective magnetic nanoparticles (MNPs), detecting a characteristic of a magnetic noise of a first MR sensor of the plurality of MR sensors, wherein the characteristic of the magnetic noise is influenced by a presence of one or more MNPs in a vicinity of the first MR sensor, and determining, based on the detected characteristic, whether the first MR sensor detected the presence of one or more MNPs in the vicinity of the first MR sensor.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Applicant: Western Digital Technologies, Inc.
    Inventors: Patrick BRAGANCA, Daniel BEDAU
  • Publication number: 20210398618
    Abstract: A device includes arrays of Non-Volatile Memory (NVM) cells. Reference sequences representing portions of a genome are stored in respective groups of NVM cells. Exact matching phase substring sequences representing portions of at least one sample read are loaded into groups of NVM cells. One or more groups of NVM cells are identified where the stored reference sequence matches the loaded exact matching phase substring sequence using the arrays at Content Addressable Memories (CAMs). Approximate matching phase substring sequences are loaded into groups of NVM cells. One or more groups of NVM cells are identified where the stored reference sequence approximately matches the loaded approximate matching phase substring sequence using the arrays as Ternary CAMs (TCAMs). At least one of the reference sequence and the approximate matching phase substring sequence for each group of NVM cells includes at least one wildcard value when the arrays are used as TCAMs.
    Type: Application
    Filed: June 22, 2020
    Publication date: December 23, 2021
    Inventors: Wen Ma, Tung Thanh Hoang, Daniel Bedau, Justin Kinney
  • Publication number: 20210391988
    Abstract: This disclosure relates to secure optical communication links. In particular, this disclosure relates to data storage devices, random access memories, host interfaces, and network layers that comprise a secure optical communication link. A data storage device comprises an optical data port to connect to an optical communication link external to the data storage device and a non-volatile storage medium to store user content data received over the optical communication link. A controller controls access to the user content data stored on the non-volatile storage medium. A cryptography engine uses a cryptographic key to perform cryptographic operations on data sent and received through the optical data port. An optical key distribution device coupled to the optical data port performs quantum key distribution over the optical communication link to provide the cryptographic key to the cryptography engine.
    Type: Application
    Filed: June 11, 2020
    Publication date: December 16, 2021
    Applicant: Western Digital Technologies, Inc.
    Inventor: Daniel BEDAU
  • Publication number: 20210379581
    Abstract: Embodiments of the present disclosure generally relate to diagnostic apparatus and uses thereof. The apparatus and methods described herein can be useful for, e.g., rapid detection of SARS- and SARS-related coronaviruses. In an embodiment is provided an apparatus for detecting a nucleotide sequence that includes a fluidic channel coupled to one or more reservoirs, the fluidic channel comprising a sample introduction component, a polymerase chain reaction component, and a detection component. The apparatus further includes a temperature control device to heat or cool the fluidic channel, one or more sensors to detect the presence or absence of a magnetic nanoparticle, and a processor coupled to the one or more sensors and to the temperature control device. In another embodiment is provided a method for detecting an analyte that includes introducing a sample to an apparatus described herein, performing one or more processes to the sample, and detecting the analyte.
    Type: Application
    Filed: June 5, 2020
    Publication date: December 9, 2021
    Inventor: Daniel BEDAU
  • Patent number: 11170852
    Abstract: Technology for operating cross-bar arrays is disclosed herein. The memory cells may each have a reversible resistivity element and a steering element comprising a diode. The cross-bar array may be operated in read mode and a bipolar programming mode. Selected memory cells may be sensed by operating the steering elements such that sense currents pass through the diodes and any sneak currents are blocked by the diodes. During bipolar programming of selected memory cells, the steering element of the selected memory cells allows current to flow in either direction through the steering element to permit bipolar programming. In some aspects, the steering element has a switch in parallel with the diode. The switches may be opened when sensing selected memory cells to pass sense currents and block sneak currents with the diodes. The switches may be closed during bipolar programming of the selected memory cells to allow bi-directional current flow.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: November 9, 2021
    Assignee: SanDisk Technologies LLC
    Inventors: Justin Phillip Kinney, Daniel Bedau
  • Publication number: 20210343338
    Abstract: A method is provided that includes reading a plurality of resistance-switching memory cells comprising a block of data, decoding the block of data using an error correction code decoder, and based on results of the decoding, selectively performing an overwrite-read process to read the block of data. The overwrite read process determines a change in resistance of the resistance-switching memory cells in response to a write pulse.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 4, 2021
    Applicant: SanDisk Technologies LLC
    Inventors: Michael K. Grobis, Daniel Bedau, Christopher J. Petti
  • Patent number: 11112468
    Abstract: A sensing device comprises a plurality of magnetoresistive (MR) sensors, at least one fluidic channel, and detection circuitry coupled to the MR sensors. Each MR sensor is configured to detect the presence of molecules (e.g., biologic molecules) labeled by magnetic nanoparticles (MNPs). The sensors are encapsulated by an insulating material that protects the sensors from the contents of the at least one fluidic channel. The insulating material has a surface within the fluidic channel that provides sites for binding the molecules to be detected. The detection circuitry is configured to detect (a) a characteristic of magnetic noise of each MR sensor, the characteristic being influenced by a presence or absence of one or more MNPs at each site, or (b) a change in resistance, current, and/or voltage drop of each MR sensor, wherein the change is influenced by the presence or absence of one or more MNPs at each site.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: September 7, 2021
    Assignee: Western Digital Technologies, Inc.
    Inventors: Patrick Braganca, Daniel Bedau