Patents by Inventor Daniel J. Kroon

Daniel J. Kroon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Labeled chemotactic peptides to image focal sites of infection or inflammation
    Patent number: 5792444
    Abstract: The invention relates to a method of detecting a site of infection or inflammation, and a method for treating such infection or inflammation, in an individual by administering to the individual a diagnostically or therapeutically effective amount of detectably labeled, therapeutic, or therapeutically-conjugated, chemotactic peptide that accumulates substantially at the infected or inflamed site, said chemotactic peptide having the general structureX--Y--Leu--Phe--?Z!.sub.n --Wwherein:X is an amino protecting group,Y is an amino acid residue,Z is a spacer sequence,n is 0 or 1, andW is a labeling or attachment substituent.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: August 11, 1998
    Assignees: The General Hospital Corporation, Johnson Matthey, Inc., Ortho Pharmaceutical Corporation
    Inventors: Alan J. Fischman, Howard F. Solomon, Claudia K. Derian, Gary J. Bridger, John D. Higgins, III, Scott K. Larsen, Pedro E. Hernandez, Robert H. Rubin, H. William Strauss, Anthony J. Fuccello, Daniel J. Kroon
  • B cell differentiating peptides and conjugates thereof
    Patent number: 4866121
    Abstract: Synthetic peptides which possess the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: June 23, 1988
    Date of Patent: September 12, 1989
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein
  • B-cell differentiating peptides
    Patent number: 4783442
    Abstract: Synthetic peptides which possess the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: November 8, 1988
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein
  • Bursopoietin
    Patent number: 4584284
    Abstract: A synthetic peptide which possesses the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: January 31, 1985
    Date of Patent: April 22, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein