Abstract: The present disclosure provides an ActRII antagonist, e.g., the ActRIIA and/or ActRIIB antagonist, e.g., an anti-ActRII receptor antibody or antigen-binding fragment thereof, e.g., bimagrumab, for treating or preventing liver disease or disorder in a subject in need thereof. The present disclosure also relates to pharmaceutical combinations comprising such ActRII antagonists and at least one further therapeutic agent in the treatment or prevention of liver disease or disorder.

Abstract: Techniques described herein are directed to transacting via social media interactions. In an example, content posted by a first user of a social media service provider and/or response(s) to the content posted by the first user of the social media service can be analyzed by computing system(s) of a payment processing service provider. The response(s) can be associated with second user(s) of the social media service provider. The computing system(s) can determine, based at least in part on the analyzing, an intent of at least the first user or the second user(s) to participate in a transaction for an item depicted in the content and can create a record indicating that item(s) depicted in the content are available for purchase by the second user(s). The record can be created at or near a time that the content is posted by the first user and used for facilitating the transaction.

Abstract: An apparatus for upholstering a truss allows an operator to staple a fabric web to the truss, rotate the truss, further staple the semi-finished truss and cut the fabric web. The truss is fully upholstered after the end surfaces of the truss are wrapped up in fabric and the fabric stapled in place. The apparatus may accommodate different size trusses. A web of fabric is pulled around at least one roller in the apparatus by rotation of two vise mechanisms on opposite sides of the truss.

Abstract: A safe assembly includes a housing having a top wall, a bottom wall, a first side wall, a second side wall, a rear wall and a door. The door having a locking mechanism to releasably lock the door in a closed position. Each of the walls includes an outer panel of steel material defining an exterior of the housing. An inner panel of steel material is spaced from the outer panel and has an exterior face facing the outer panel. The exterior face comprises a highly reflective surface. An insulating material is positioned between and fills a space between the outer and inner panels. A plurality of mating flanges is attached to the walls such that each of the walls includes a mating flange securable to a mating flange on one more adjacently positioned one of the walls to form the completed housing.

Abstract: A robotic cleaner includes a housing, a suction conduit with an opening, and a leading roller mounted in front of a brush roll. An inter-roller air passageway may be defined between the leading roller and the brush roll wherein the lower portion of the leading roller is exposed to a flow path to the suction conduit and an upper portion of the leading roller is outside of the flow path. Optionally, a combing unit includes a plurality of combing protrusions extending into the leading roller and having leading edges not aligned with a center of the leading roller. Optionally, a sealing strip is located along a rear side of the opening and along a portion of left and right sides of the opening. The underside may define side edge vacuum passageways extending from the sides of the housing partially between the leading roller and the sealing strip towards the opening.

Abstract: A surface cleaning head with dual rotating agitators (e.g., a leading roller and a brush roll) may be used to facilitate capturing of debris in the air flow into a suction conduit on the underside of the surface cleaning head. The leading roller is generally positioned adjacent to and in advance of the opening of the suction conduit. The rotating brush roll may be located in the suction conduit with the leading roller located in front of and spaced from the brush roll, forming an inter-roller air passageway therebetween. The leading roller may provide a softer cleaning element than the brush roll and may also have an outside diameter that is less than the outside diameter of the brush roll. The surface cleaning head may also include debriding protrusions contacting the leading roller and/or a leading bumper that extends in front of the leading roller.

Abstract: The articulated-arm robot has a robot arm with an arm element movable via a joint and a sensor for continuously measuring a status parameter of the joint. The articulated-arm robot also has an optical signaling device arranged on the robot arm in spatial assignment to the joint and an assessment device for continuously assessing the measured status parameter in a joint-specific manner and for controlling the signaling device on the basis of the assessment result.

Abstract: A robotic cleaner includes a housing, a suction conduit with an opening, and a leading roller mounted in front of a brush roll. An inter-roller air passageway may be defined between the leading roller and the brush roll wherein the lower portion of the leading roller is exposed to a flow path to the suction conduit and an upper portion of the leading roller is outside of the flow path. Optionally, a combing unit includes a plurality of combing protrusions extending into the leading roller and having leading edges not aligned with a center of the leading roller. Optionally, a sealing strip is located along a rear side of the opening and along a portion of left and right sides of the opening. The underside may define side edge vacuum passageways extending from the sides of the housing partially between the leading roller and the sealing strip towards the opening.

Abstract: The invention relates to a measurement system for detection of conduction faults of a device or equipment, comprising an evaluation unit and at least one sensor unit, wherein the measurement system is furthermore adapted to determine, in regard to a fault, whether the fault is higher or lower in frequency with respect to a predetermined limit frequency, and the measurement system is furthermore adapted to provide data in regard to one fault or multiple faults.

Abstract: The disclosure concerns the use of LIK066 in the treatment, prevention or delay of non-alcoholic steatohepatitis.

Abstract: An apparatus for upholstering a truss allows an operator to staple a fabric web to the truss, rotate the truss, further staple the semi-finished truss and cut the fabric web. The truss is fully upholstered after the end surfaces of the truss are wrapped up in fabric and the fabric stapled in place. The apparatus may accommodate different size trusses. A web of fabric is pulled around at least one roller in the apparatus by rotation of two vise mechanisms on opposite sides of the truss.

Abstract: Various embodiments include a sensor device for determining an electrical conductivity of a fluid and a speed of sound in the fluid comprising: a first electrode; a second electrode electrically isolated from the first electrode; and a sound transducer to emit sound waves into the fluid toward the first electrode and/or the second electrode, and to receive sound waves reflected back by the respective electrode to determine the speed of sound in the fluid. Each electrode is in direct contact with the fluid and is operable to determine the electrical conductivity of the fluid using the conductive principle.

Abstract: An assembly of vessel and turret is provided. The vessel comprises a moonpool and the turret is mounted in said moonpool for a rotation around a turret axis relative to the vessel. The turret comprises a chain table to which mooring lines are connected and through which risers are conveyed, and a turret table vertically spaced above the chain table and connected therewith by a connecting structure. The connecting structure comprises at least three vertically extending columns positioned such at angular intervals that radially outer sides of the columns are located in the vicinity of an outer circumference of the turret. The risers are conveyed through the chain table in such a way that riser sections above the chain table extend towards the turret table within an internal space of the columns.

Abstract: A conveyor chain includes a plurality of side link assemblies and flight arm assemblies coupled together to form an elongated chain. The flight arm assemblies include a pair of opposing flight arms positioned on either side of the chain with the flight arms each including an elongated body formed with and extending from an integral base and a vertical sprocket opening formed in the integral base. The vertical sprocket opening is configured for engaging a tooth of a drive sprocket to drive the flight arm. The side link assemblies include a pair of opposing side straps positioned on either side of the chain each including a base and a pair of side strap bosses extending outwardly from the base.

Abstract: A surface cleaning head with a leading roller may be used to facilitate capturing of debris in the air flow into a suction conduit on the underside of the surface cleaning head. The leading roller is generally positioned adjacent to and in advance of the opening of the suction conduit. The surface cleaning head may have dual agitators—a leading roller and a rotating brush roll—with the leading roller being located in front of the brush roll. The leading roller may have a smaller diameter than the brush roll and may provide a softer cleaning element. The leading roller may also have a bottom portion exposed to the flow path to the suction conduit and at least a top half that is not exposed to that flow path. The leading roller may also float relative to the surface cleaning head and/or may be adjustable relative to the brush roll.

Abstract: A method and a device for the mutual monitoring and/or control of a multiplicity of autonomous technical systems which are at least partially interconnected to one another via a communication network is provided. At least one of the autonomous technical systems is embodied as a monitoring autonomous technical system and monitors the operating behaviour of other autonomous technical systems. Since a specified first rule, the monitoring autonomous technical system detects an operating behavior, which is contrary to the rule, of a first autonomous technical system and generates a status message about the operating behavior which is contrary to the rule therefrom. Depending on the evaluation, a control rule is derived for the first autonomous technical system and communicated to a control module which is assigned to the first autonomous technical system. The operating behavior of the first autonomous technical system is controlled on the basis of the control rule.

Abstract: The disclosure concerns the use of LIK066 in the treatment, prevention or delay of non-alcoholic steatohepatitis.

Abstract: A safe assembly includes a housing having a top wall, a bottom wall, a first side wall, a second side wall, a rear wall and a door. The door having a locking mechanism to releasably lock the door in a closed position. Each of the walls includes an outer panel of steel material defining an exterior of the housing. An inner panel of steel material is spaced from the outer panel and has an exterior face facing the outer panel. The exterior face comprises a highly reflective surface. An insulating material is positioned between and fills a space between the outer and inner panels. A plurality of mating flanges is attached to the walls such that each of the walls includes a mating flange securable to a mating flange on one more adjacently positioned one of the walls to form the completed housing.

Abstract: An apparatus for upholstering a truss allows an operator to staple a fabric web to the truss, rotate the truss, further staple the semi-finished truss and cut the fabric web. The truss is fully upholstered after the end surfaces of the truss are wrapped up in fabric and the fabric stapled in place. The apparatus may accommodate different size trusses. A web of fabric is pulled around at least one roller in the apparatus by rotation of two vise mechanisms on opposite sides of the truss.

Abstract: An apparatus for upholstering a truss allows an operator to staple a fabric web to the truss, rotate the truss, further staple the semi-finished truss and cut the fabric web. The truss is fully upholstered after the end surfaces of the truss are wrapped up in fabric and the fabric stapled in place. The apparatus may accommodate different size trusses. A web of fabric is pulled around at least one roller in the apparatus by rotation of two vise mechanisms on opposite sides of the truss.