Abstract: There are described a system and method for performing ultrasound testing of a component comprising a first material layer and a second material layer bonded by an adhesive layer. The method comprises applying input ultrasound to the component to cause longitudinal propagation of ultrasonic guided waves through the first material layer and the adhesive layer; acquiring acoustic waves from the component, wherein the acoustic waves produced by the longitudinal propagation of the ultrasonic guided waves; generating a signal representation of the acoustic waves; comparing the signal representation of the acoustic waves to a plurality of reference signals to identify a characteristic of the adhesive layer; and outputting an output signal indicative of the characteristic of the adhesive layer.

Abstract: Aspects described herein include systems and methods for determining addresses for assets, prioritizing the addresses for inspection by users, and applying natural language processing techniques to unstructured text input by the users. According to some aspects, a message may be received that includes unstructured text that was input by a user. The unstructured text may be associated with an inspection, by the user, of an address for an asset. One or more natural language techniques may be applied to the unstructured text to, among other things, facilitate the determination and sending of a response message to the unstructured text in an automated fashion. The response message may, if the asset was not found, include another address as a suggestion for the user to inspect for the asset. This suggested address may be determined based on changes to address priority that were caused by processing of the unstructured text.

Abstract: Aspects described herein include systems and methods for determining addresses for assets, prioritizing the addresses for inspection by users, and applying natural language processing techniques to unstructured text input by the users. According to some aspects, a message may be received that includes unstructured text that was input by a user. The unstructured text may be associated with an inspection, by the user, of an address for an asset. One or more natural language techniques may be applied to the unstructured text to, among other things, facilitate the determination and sending of a response message to the unstructured text in an automated fashion. The response message may, if the asset was not found, include another address as a suggestion for the user to inspect for the asset. This suggested address may be determined based on changes to address priority that were caused by processing of the unstructured text.

Abstract: An interface device for performing off-chip coupling in optical waveguides includes an optical waveguide core for propagating light of a particular wavelength or a plurality of wavelengths and an array of radiative elements configured to change the propagation direction of the light. The optical waveguide core is configured to control the effective refractive index of the propagation mode of the light. The device can thus serve as an optical antenna for coupling between a waveguide mode and a free-space propagating beam or a plurality of free-space propagating beams in an arrayed configuration.

Abstract: Techniques are described for obtaining current location data for a non-traditional telephony endpoint for emergency calling purposes. An emergency services (ES) provider receives, from a telephony server responding to a telecommunication session establishment request from a telephony endpoint, a location registration request, the location registration request including telephony endpoint identification information and a mobile device telephone number. The ES provider may send a short message service (SMS) message to the mobile device telephone number, the SMS message including an executable registration link that when executed on a mobile device receiving the SMS message causes the mobile device to retrieve location data of the mobile device. The ES provider may then receive the current location data from the mobile device and store it and the telephony endpoint identification information for subsequent use should a 911 call be made from that telephony endpoint.

Abstract: Techniques are described for obtaining current location data for a non-traditional telephony endpoint for emergency calling purposes. An emergency services (ES) provider receives, from a telephony server responding to a telecommunication session establishment request from a telephony endpoint, a location registration request, the location registration request including telephony endpoint identification information and a mobile device telephone number. The ES provider may send a short message service (SMS) message to the mobile device telephone number, the SMS message including an executable registration link that when executed on a mobile device receiving the SMS message causes the mobile device to retrieve location data of the mobile device. The ES provider may then receive the current location data from the mobile device and store it and the telephony endpoint identification information for subsequent use should a 911 call be made from that telephony endpoint.

Abstract: DNA aptamers that recognize the human galectin-1 hGal1 with a very high degree of binding affinity and specificity, and inhibit hGal1-induced hemagglutination, besides presenting antiproliferative effects in seven human solid tumor cell lines are disclosed. The cytotoxicity tests demonstrated that, among 41 sequences tested, four of them (SEQ ID NO.: 04, SEQ ID NO.: 09, SEQ ID NO.:10 and, SEQ ID NO.:12) have the best capacity of inhibiting the cell growth in tumor cell. Additionally, the aptamers developed in the present invention will be used, for example, in the treatment of disorders related to the binding of human galectin-1 to a ligand in a mammal, wherein said disorder is selected from the group consisting of inflammation, fibrosis, septic shock, cancer, autoimmune diseases, metabolic disorders, heart disease, heart failure, pathological angiogenesis, and eye diseases, mainly cancer.

Abstract: Techniques are described for obtaining current location data for a non-traditional telephony endpoint for emergency calling purposes. An emergency services (ES) provider receives, from a telephony server responding to a telecommunication session establishment request from a telephony endpoint, a location registration request, the location registration request including telephony endpoint identification information. The ES provider may push a quick response (QR) code to the telephony endpoint, the QR code when scanned by a mobile device causes the mobile device to retrieve its current location data. The ES provider may then receive the current location data from the mobile device and store it and the telephony endpoint identification information for subsequent use should a 911 call be made from that telephony endpoint. The ES provider may then send the telephony server an authorization acknowledgement for the telecommunication session establishment request.

Abstract: An effective therapeutic agent for subretinal hyperreflective material or retinal diseases accompanying subretinal hyperreflective material is provided by the present invention. Specifically, a therapeutic agent for subretinal hyperreflective material or a retinal disease accompanying subretinal hyperreflective material, containing an aptamer that binds to FGF2 or a salt thereof is provided.

Abstract: There are described a system and method for performing ultrasound testing of a component comprising a first material layer and a second material layer bonded by an adhesive layer. The method comprises applying input ultrasound to the component to cause longitudinal propagation of ultrasonic guided waves through the first material layer and the adhesive layer; acquiring acoustic waves from the component, wherein the acoustic waves produced by the longitudinal propagation of the ultrasonic guided waves; generating a signal representation of the acoustic waves; comparing the signal representation of the acoustic waves to a plurality of reference signals to identify a characteristic of the adhesive layer; and outputting an output signal indicative of the characteristic of the adhesive layer.

Abstract: A software development system is provided for creating and testing applications. The software development system includes a non-transitory computer-readable medium and a processor in communication with the medium.

Abstract: Provided are methods for treatment of cancer. Also provided are methods for treating a patient susceptible or suspected of being susceptible with anti-CD47 therapies.

Abstract: DNA aptamers that recognize the human galectin-1 hGal1 with a very high degree of binding affinity and specificity, and inhibit hGal1-induced hemagglutination, besides presenting antiproliferative effects in seven human solid tumor cell lines are disclosed. The cytotoxicity tests demonstrated that, among 41 sequences tested, four of them (SEQ ID NO.: 04, SEQ ID NO.: 09, SEQ ID NO.:10 and, SEQ ID NO.:12) have the best capacity of inhibiting the cell growth in tumor cell. Additionally, the aptamers developed in the present invention will be used, for example, in the treatment of disorders related to the binding of human galectin-1 to a ligand in a mammal, wherein said disorder is selected from the group consisting of inflammation, fibrosis, septic shock, cancer, autoimmune diseases, metabolic disorders, heart disease, heart failure, pathological angiogenesis, and eye diseases, mainly cancer.

Abstract: The invention is directed to a hydratable concentrated surfactant composition. The composition is pourable, easy to dilute, substantially free of sulfate and oil, comprises a C6-C14 acid, alcohol or both, anionic surfactant and an amphoteric surfactant, zwitterionic surfactant or both. The composition is in lamellar phase and thickens and transforms to an isotropic phase upon dilution. The composition can be used as a concentrate in small volumes and diluted as used and needed or can be diluted with water in refill packaging to ensure a reduction in plastic waste.

Abstract: The present invention concerns a cooling element (100) of an electrical storage device (200) for a motor vehicle, comprising at least one first wall (110) extending primarily in a first plane and in which is created at least one first channel (113) and at least one second wall (120) extending primarily in a second plane and which is created at least one second channel (123), the first channel (113) and the second channel (123) being adapted to be taken by a heat transport fluid. According to the invention the first plane in which the first wall (110) extends and the second plane in which the second wall (120) extends intersect and at least the first wall (110) is configured to support the electrical storage device (200).

Abstract: The present invention consists in a thermal module (1) for a motor vehicle, comprising a main radiator (2) and at least one auxiliary heat exchanger (3, 4) mounted on the main radiator (2) by means of a junction member (13) disposed between the main radiator (2) and at least one first auxiliary heat exchanger (3), The junction member (13) is principally formed of at least two shaft bearings (14, 15) attached to the first auxiliary heat exchanger (3) and nested inside respective open flanges (16, 17) formed on one of the lateral sides (7, 8) of the main radiator (2). Secondarily, the junction member (13) carries a plurality of auxiliary heat exchangers (3, 4) fixed to one another in staggered succession and composing a thermal submodule mounted on the main radiator (2) by means of the junction member (13).

Abstract: The invention concerns an attachment device (3) for a heat exchanger (2) comprising a core (23) for exchanging heat between a first fluid and a second fluid, said core (23) being provided with collectors (21) for the first fluid, said exchanger (2) comprising a cylinder (25), said cylinder (25) and one of said collectors (21) allowing the passage of said first fluid from one to the other, said attachment device (3) comprising a body, which is set up in order to close said cylinder (25), and an extension which allows the core (23) to be secured to a holder (4). The invention also concerns a cylinder (25) which comprises such an attachment device (3), a heat exchanger (2) which comprises such a cylinder (25) and a heat exchanging module which comprises such a heat exchanger (2).

Abstract: The present invention consists in a thermal module (1) for a motor vehicle, comprising a main radiator (2) and at least one auxiliary heat exchanger (3, 4) mounted on the main radiator (2) by means of a junction member (13) disposed between the main radiator (2) and at least one first auxiliary heat exchanger (3), The junction member (13) is principally formed of at least two shaft bearings (14, 15) attached to the first auxiliary heat exchanger (3) and nested inside respective open flanges (16, 17) formed on one of the lateral sides (7, 8) of the main radiator (2). Secondarily, the junction member (13) carries a plurality of auxiliary heat exchangers (3, 4) fixed to one another in staggered succession and composing a thermal submodule mounted on the main radiator (2) by means of the junction member (13).

Abstract: The invention concerns an attachment device (3) for a heat exchanger (2) comprising a core (23) for exchanging heat between a first fluid and a second fluid, said core (23) being provided with collectors (21) for the first fluid, said exchanger (2) comprising a cylinder (25), said cylinder (25) and one of said collectors (21) allowing the passage of said first fluid from one to the other, said attachment device (3) comprising a body, which is set up in order to close said cylinder (25), and an extension which allows the core (23) to be secured to a holder (4). The invention also concerns a cylinder (25) which comprises such an attachment device (3), a heat exchanger (2) which comprises such a cylinder (25) and a heat exchanging module which comprises such a heat exchanger (2).

Abstract: The device according to the invention controls a polyphase inverter (10, 14, 17) intended for powering from a DC current source (CC) a polyphase rotating electric machine (1). The device is of the type of those generating commutation functions driving commutation elements (9, 13) of the inverter in such a way as to obtain a reduction of the losses in the commutation elements and a decrease of an effective current in a decoupling capacitor (16) of the source (CC). According to the invention, this reduction and this decrease are obtained by means of a set of control strategies (21, 24) determining the commutation functions by using additional degrees of freedom of the polyphase machine (1) with respect to a three-phase reference machine. The polyphase machine comprises first and second phase windings forming a first three-phase system (2, 3, 4) and a second three-phase system (5, 6, 7) with distinct neutral points (11, 15) offset angularly by a predetermined angle of offset (?).