Patents by Inventor Daniel Tavares

Daniel Tavares has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD37-Binding Molecules and Immunoconjugates Thereof
    Publication number: 20190218303
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to CD37 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Application
    Filed: December 17, 2018
    Publication date: July 18, 2019
    Inventors: Jutta Deckert, Peter Park, Daniel Tavares, Lingyun Rui
  • Folate receptor 1 antibodies and immunoconjugates and uses thereof
    Patent number: 10301385
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: May 28, 2019
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher
  • CD37-binding molecules and immunoconjugates thereof
    Patent number: 10202460
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to CD37 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: February 12, 2019
    Assignee: Debiopharm International, S.A.
    Inventors: Jutta Deckert, Peter Park, Daniel Tavares, Lingyun Rui
  • ANTIBODIES AND ASSAYS FOR DETECTION OF FOLATE RECEPTOR 1
    Publication number: 20190023805
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: June 7, 2018
    Publication date: January 24, 2019
    Inventors: Olga AB, Daniel TAVARES, Julianto SETIADY, Sharron LADD, Christina N. CARRIGAN, Lingyun RUI
  • Diagnostic assays and kits for detection of folate receptor 1
    Patent number: 10180432
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: January 15, 2019
    Assignee: ImmunoGen, inc.
    Inventors: Christina N. Carrigan, Olga Ab, Daniel Tavares, Beni B. Wolf
  • ANTI-CD33 ANTIBODIES AND METHOD FOR TREATMENT OF ACUTE MYELOID LEUKEMIA USING THE SAME
    Publication number: 20180362646
    Abstract: The present invention relates to antibodies that bind CD33. More particularly, the invention relates to anti-CD33 antibodies, fragments and homologues of these antibodies, humanized and resurfaced versions of these antibodies, functional equivalents and improved versions of these antibodies, immunoconjugates and compositions comprising these antibodies, and the uses of same in diagnostic, research and therapeutic applications. The invention also relates to a polynucleotide encoding these antibodies, vectors comprising the polynucleotides, host cells transformed with polynucleotides and methods of producing these antibodies.
    Type: Application
    Filed: May 14, 2018
    Publication date: December 20, 2018
    Inventors: Mary G. Hoffee, Daniel Tavares, Robert J. Lutz
  • Anti-CD123 antibodies and conjugates and derivatives thereof
    Patent number: 10077313
    Abstract: The present invention generally relates to antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to CD123 antigen (the ? chain of the interleukine 3 receptor, or IL-3R?). The present invention also relates to methods of using such CD123-binding molecules for diagnosing and treating diseases, such as B-cell malignancies.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: September 18, 2018
    Assignee: IMMUNOGEN, INC.
    Inventors: Yelena Kovtun, Daniel Tavares, Lingyun Rui, Thomas Chittenden
  • ANTIBODIES AND ASSAYS FOR DETECTION OF CD37
    Publication number: 20180244795
    Abstract: The invention generally relates to antibodies that bind to human CD37 and diagnostic assays for CD37-based therapies.
    Type: Application
    Filed: August 26, 2016
    Publication date: August 30, 2018
    Applicant: DEBIOPHARM INTERNATIONAL,S.A.
    Inventors: Jutta DECKERT, Daniel TAVARES, LingYun RUI, Sven LOEBRICH, Megan KELLY
  • Methods of treating cancer in a patient by administering anti-folate-receptor-1 (FOLR1) antibodies
    Patent number: 10017578
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 10, 2018
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Julianto Setiady, Sharron Ladd, Christina N. Carrigan, Lingyun Rui
  • Anti-CD33 antibodies and methods for treatment of acute myeloid leukemia using the same
    Patent number: 10000566
    Abstract: The present invention relates to antibodies that bind CD33. More particularly, the invention relates to anti-CD33 antibodies, fragments and homologues of these antibodies, humanized and resurfaced versions of these antibodies, functional equivalents and improved versions of these antibodies, immunoconjugates and compositions comprising these antibodies, and the uses of same in diagnostic, research and therapeutic applications. The invention also relates to a polynucleotide encoding these antibodies, vectors comprising the polynucleotides, host cells transformed with polynucleotides and methods of producing these antibodies.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: June 19, 2018
    Assignee: IMMUNOGEN, INC.
    Inventors: Mary G. Hoffee, Daniel Tavares, Robert J. Lutz
  • Diagnostic Assays and Kits for Detection of Folate Receptor 1
    Publication number: 20180003715
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: June 12, 2017
    Publication date: January 4, 2018
    Inventors: Christina N. CARRIGAN, Olga AB, Daniel TAVARES, Beni B. WOLF
  • NOVEL ANTI-CD38 ANTIBODIES FOR THE TREATMENT OF CANCER
    Publication number: 20170343550
    Abstract: Antibodies, humanized antibodies, resurfaced antibodies, antibody fragments, derivatized antibodies, and conjugates of same with cytotoxic agents, which specifically bind to CD38, are capable of killing CD3830 cells by apoptosis, antibody-dependent cell-mediated cytotoxicity (ADCC), and/or complement-dependent cytotoxicity (CDC). Said antibodies and fragments thereof may be used in the treatment of tumors that express CD38 protein, such as multiple myeloma, chronic lymphocytic leukemia, chronic rnyelogenous leukemia, acute myelogenous leukemia, or acute lymphocytic leukemia, or the treatment of autoimmune and inflammatory diseases such as systemic lupus, rheumatoid arthritis, multiple sclerosis, erythematosus, and asthma.
    Type: Application
    Filed: January 9, 2017
    Publication date: November 30, 2017
    Inventors: Peter U. PARK, Laura M. BARTLE, Anna SKALETSKAYA, Viktor GOLDMAKHER, Daniel TAVARES, Jutta DECKERT, Vincent MIKOL, Veronique BLANC
  • Folate Receptor 1 Antibodies and Immunoconjugates and Uses Thereof
    Publication number: 20170327575
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 16, 2017
    Applicant: ImmunoGen, Inc.
    Inventors: Olga AB, Daniel TAVARES, Lingyun RUI, Gillian PAYNE, Viktor S. GOLDMAKHER
  • ANTIBODIES AND ASSAYS FOR DETECTION OF FOLATE RECEPTOR 1
    Publication number: 20170306041
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Application
    Filed: March 29, 2017
    Publication date: October 26, 2017
    Inventors: Olga AB, Daniel TAVARES, Julianto SETIADY, Sharron LADD, Christina N. CARRIGAN, Lingyun RUI
  • Diagnostic assays and kits for detection of folate receptor 1
    Patent number: 9702881
    Abstract: The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: July 11, 2017
    Assignee: ImmunoGen, Inc.
    Inventors: Christina N. Carrigan, Olga Ab, Daniel Tavares, Beni B. Wolf, Nathan E. Testa
  • Antibodies that specifically bind to the EphA2 receptor
    Patent number: 9676864
    Abstract: The present disclosure relates to an antibody or an epitope-binding fragment thereof that specifically binds to an EphA2 receptor. It further relates to a conjugate comprising a cytotoxic agent which is covalently bound to the antibody and a method for preparing such a conjugate.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: June 13, 2017
    Assignee: SANOFI
    Inventors: Herve Bouchard, Alain Commercon, Claudia Fromond, Vincent Mikol, Fabienne Parker, Ingrid Sassoon, Daniel Tavares
  • Folate receptor 1 antibodies and immunoconjugates and uses thereof
    Patent number: 9670279
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: June 6, 2017
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher
  • Folate receptor 1 antibodies and immunoconjugates and uses thereof
    Patent number: 9670278
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: June 6, 2017
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher
  • Folate receptor 1 antibodies and immunoconjugates and uses thereof
    Patent number: 9670280
    Abstract: Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: June 6, 2017
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Lingyun Rui, Gillian Payne, Viktor S. Goldmakher
  • EPHA2 receptor antagonist antibodies
    Patent number: RE47123
    Abstract: Antagonistic antibodies that specifically bind to and inhibit Class A Eph receptors are provided. Also provided are cytotoxic conjugates, pharmaceutical compositions and kits comprising these antibodies.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: November 13, 2018
    Assignee: SANOFI
    Inventors: Veronique Blanc, Claudia Fromond, Fabienne Parker, Jiawen Han, Daniel Tavares, Chonghui Zhang, Min Li, Xiao-Mai Zhou, Michel Streuli