Patents by Inventor Daniel W. Bradbury

Daniel W. Bradbury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks
    Patent number: 11209427
    Abstract: Devices and methods are provided for the detection of CSF in a biological sample. In certain embodiments the device is a lateral flow device comprising: a porous substrate; a sample addition zone disposed on or in said porous substrate; a detection zone disposed on or in said porous substrate where said detection zone comprises at least a first test line (T1) and a second test line (T2) each test line comprising binding moieties that bind a complex formed between beta-trace protein (betaTP) and an indicator attached to a betaTP binding molecule; wherein said porous substrate defines a flow path through which a sample applied to the sample addition zone flows under capillary action away from said sample addition zone into said detection zone.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: December 28, 2021
    Assignee: The Regents of the University of California
    Inventors: Daniel T. Kamei, Maie A. ST John, Zachary D. Taylor, Daniel W. Bradbury, Ashley E. Kita
  • SEMI-QUANTITATIVE LATERAL-FLOW IMMUNOASSAY FOR THE DETECTION OF CSF LEAKS
    Publication number: 20200033336
    Abstract: Devices and methods are provided for the detection of CSF in a biological sample. In certain embodiments the device is a lateral flow device comprising: a porous substrate; a sample addition zone disposed on or in said porous substrate; a detection zone disposed on or in said porous substrate where said detection zone comprises at least a first test line (T1) and a second test line (T2) each test line comprising binding moieties that bind a complex formed between beta-trace protein (betaTP) and an indicator attached to a betaTP binding molecule; wherein said porous substrate defines a flow path through which a sample applied to the sample addition zone flows under capillary action away from said sample addition zone into said detection zone.
    Type: Application
    Filed: March 26, 2018
    Publication date: January 30, 2020
    Inventors: Daniel T. Kamei, Maie A. ST John, Zachary D. Taylor, Daniel W. Bradbury, Ashley E. Kita