Patents by Inventor David A Stenger
David A Stenger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20200315025Abstract: Patterns of homogenous, electroless-plated metals within and on one or both sides of a porous substrate (such as nanocellulose sheets) enable the formation of an matrix of metal within pores of the substrate that can connect patterns on both sides of the substrate. These can serve as circuits with applications in, for example, wearable electronics.Type: ApplicationFiled: March 24, 2020Publication date: October 1, 2020Inventors: Jonathan D. Yuen, David A. Stenger, Daniel Zabetakis, Scott Walper, Banahalli R. Ratna
-
Publication number: 20190033247Abstract: An electrochemical cell includes a working electrode in contact with an aqueous electrolyte solution, a counter electrode in contact with the aqueous electrolyte solution, and a reference electrode in contact with the aqueous electrolyte solution. The working electrode comprises a plasma modified epitaxial synthesized graphene surface fabricated on SiC.Type: ApplicationFiled: July 30, 2018Publication date: January 31, 2019Inventors: Scott A. Trammell, Rachael L. Myers-Ward, Sandra C. Hangarter, Daniel Zabetakis, David A. Stenger, David Kurt Gaskill, Scott G. Walton
-
Patent number: 9857293Abstract: Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to voltammetry and/or spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is the deep eutectic solvent consisting of a mixture of ethylene glycol and choline chloride.Type: GrantFiled: November 18, 2016Date of Patent: January 2, 2018Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Daniel Zabetakis, Scott A. Trammell, Walter J. Dressick, David A. Stenger, Jasenka Verbarg
-
Patent number: 9857294Abstract: Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is a deep eutectic solvents consisting of a mixture of ethylene glycol and choline chloride.Type: GrantFiled: November 18, 2016Date of Patent: January 2, 2018Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Daniel Zabetakis, Scott A. Trammell, Walter J. Dressick, David A. Stenger, Jasenka Verbarg
-
Publication number: 20170343471Abstract: Systems and methods are provided for identification of a detection event relevant in applications focused on real-time or near real-time reporting in a continuous monitoring application. A controller collects data from a plurality of sensors and compares recent data to background data to determine whether an event has occurred. A system in accordance with an embodiment of the present disclosure is considered to have detected an event of interest when at least a specified minimum number of sensors report a detection event at the same time.Type: ApplicationFiled: May 27, 2017Publication date: November 30, 2017Inventors: Anthony P. Malanoski, Brandy J. White, Jeffrey S. Erickson, David A. Stenger
-
Publication number: 20170074785Abstract: Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is a deep eutectic solvents consisting of a mixture of ethylene glycol and choline chloride.Type: ApplicationFiled: November 18, 2016Publication date: March 16, 2017Inventors: Daniel Zabetakis, Scott A. Trammell, Walter J. Dressick, David A. Stenger, Jasenka Verbarg
-
Publication number: 20170074825Abstract: Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to voltammetry and/or spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is the deep eutectic solvent consisting of a mixture of ethylene glycol and choline chloride.Type: ApplicationFiled: November 18, 2016Publication date: March 16, 2017Inventors: Daniel Zabetakis, Scott A. Trammell, Walter J. Dressick, David A. Stenger, Jasenka Verbarg
-
Patent number: 9557296Abstract: Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to voltammetry and/or spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is selected from the group consisting of polar aprotic or protic solvents having a boiling point of at least 100° C., room temperature ionic liquids, and deep eutectic solvents.Type: GrantFiled: August 27, 2014Date of Patent: January 31, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Daniel Zabetakis, Scott A. Trammell, Walter J. Dressick, David A. Stenger, Jasenka Verbarg
-
Patent number: 9430610Abstract: The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample.Type: GrantFiled: April 10, 2008Date of Patent: August 30, 2016Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Brian K Agan, Eric H Hanson, Russell P Kruzelock, Baochuan Lin, Robb K Rowley, Donald Seto, David A Stenger, Jennifer Johnson, Clark J Tibbetts, Dzung C Thach, Gary J Vora, Elizabeth A Walter, Zheng Wang
-
Publication number: 20160061775Abstract: Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to voltammetry and/or spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is selected from the group consisting of polar aprotic or protic solvents having a boiling point of at least 100° C., room temperature ionic liquids, and deep eutectic solvents.Type: ApplicationFiled: August 27, 2014Publication date: March 3, 2016Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Daniel Zabetakis, Scott A. Trammell, Walter J. Dressick, David A. Stenger, Jasenka Verbarg
-
Patent number: 9096849Abstract: A method of: providing a solid surface having a dendrimer molecule bound thereto and a single-stranded probe nucleic acid immobilized to the dendrimer; contacting the solid surface with a sample suspected or known to contain a double-stranded complimentary target nucleic acid; denaturing the target nucleic acids at thermal conditions and in a salt concentration sufficient to denature the target nucleic acids to produce denatured nucleic acids; and cooling the sample to allow hybridization of the denatured nucleic acids to the probe nucleic acids. An article having: one or more paramagnetic microbeads; a dendrimer molecule bound to the beads; and a probe nucleic acid immobilized to the dendrimer.Type: GrantFiled: May 21, 2007Date of Patent: August 4, 2015Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Marie J. Archer, Baochuan Lin, David A Stenger
-
Patent number: 8965710Abstract: An apparatus having within or as part of a housing; a sample port; a microarray port; a lysis module; a purification module for containing a solid phase for binding of oligonucleotides; a thermocycling module for containing a polymerase chain reaction; a fragmentation module; and a microarray module for holding a microarray and a liquid in contact with the microarray. The apparatus is configured to be coupled to a device for: pumping a liquid through, in order, the lysis, purification, thermocycling, fragmentation, and microarray modules; sonicating any contents of the lysis module; thermocycling the thermocycling module to perform the polymerase chain reaction; heating the fragmentation module to fragment any oligonucleotides contained therein; circulating a fluid over the surface of the microarray; and performing one or more washing or staining steps on the microarray.Type: GrantFiled: November 14, 2006Date of Patent: February 24, 2015Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Frances S Ligler, David A Stenger, Jeff Erickson, Marie Archer
-
Publication number: 20120035857Abstract: A computer-implemented biological sequence identifier (CIBSI) system and method for selecting a subsequence from biological sequence data according to at least one selection parameter. The at least one selection parameter corresponds to a likelihood of returning a meaningful result from a similarity search.Type: ApplicationFiled: August 17, 2011Publication date: February 9, 2012Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVYInventors: David A. Stenger, Jennifer Thornton
-
Patent number: 8032310Abstract: A computer-implemented biological sequence identifier (CIBSI) system and method for selecting a subsequence from biological sequence data according to at least one selection parameter. The at least one selection parameter corresponds to a likelihood of returning a meaningful result from a similarity search.Type: GrantFiled: July 2, 2005Date of Patent: October 4, 2011Assignee: The United States of America as represented by the Secretary of the NavyInventors: David A Stenger, Jennifer Thornton
-
Publication number: 20110183856Abstract: The present invention provides a specific set of gene expression markers from peripheral blood leukocytes that are indicative of a host response to exposure, response, and recovery infectious pathogen infections. The present invention further provides methods for identifying the specific set of gene expression markers, methods of monitoring disease progression and treatment of infectious pathogen infections, methods of prognosing the onset of an infectious pathogen infection, and methods of diagnosing an infectious pathogen infection and identifying the pathogen involved.Type: ApplicationFiled: February 26, 2010Publication date: July 28, 2011Applicants: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian K. Agan, Eric H. Hanson, Michael J. Jenkins, Baochuan Lin, Chris C. Olsen, Robb K. Rowley, David A. Stenger, Dzung C. Thach, Clark J. Tibbetts, Elizabeth A. Walter, Jinny Lin Liu
-
Patent number: 7979446Abstract: A method of: submitting reference sequences to a taxonomic database to produce taxonomic results; and reporting a taxonomic identification based on the taxonomic results. The reference sequences are the output of genetic database queries that return a score for each reference sequence. A method for processing a biological sequence obtained from an assay by: converting base calls located in a predetermined list of positions within the biological sequence to N; and determining the ratio of single nucleotide polymorphisms in the biological sequence relative to a reference sequence. Each entry in the predetermined list of positions represents the capability of a substance hybridizing to a microarray used to generate the biological sequence. The substance is not the nucleic acid of a target pathogen.Type: GrantFiled: November 12, 2009Date of Patent: July 12, 2011Assignee: The United States of America as represented by the Secretary of the NavyInventors: Anthony P. Malanoski, Baochuan Lin, Joel M Schnur, David A Stenger
-
Patent number: 7785769Abstract: The use of sugar-containing hydrogels as very highly porous, aqueous support material for the immobilization of oligonucleotides, peptides, proteins, antigens, antibodies, polysaccharides, and other biomolecules for sensor applications. Unusually large sizes of interconnected pores allow large target molecules to pass rapidly into and through the gel and bind to immobilized biomolecules. Sugar-containing hydrogels have extremely low non-specific absorption of labeled target molecules, providing low background levels. Some hydrogel materials do not have this type of homogeneous interconnected macroporosity, thus large target molecules cannot readily diffuse through them. Additionally, they nearly always experience non-specific absorption of labeled target molecules, limiting their usefulness in sensor applications. A method is provided for preparing sugar polyacrylate hydrogels with functional chemical groups which covalently bond oligonucleotides and peptides.Type: GrantFiled: July 25, 2003Date of Patent: August 31, 2010Assignee: The United States of America as reprsented by the Secretary of the NavyInventors: Mark S. Spector, David A. Stenger, Charles H. Patterson, Jr., Brett D. Martin, Paul T. Charles
-
Patent number: 7785770Abstract: The use of sugar-containing hydrogels as very highly porous, aqueous support material for the immobilization of oligonucleotides, peptides, proteins, antigens, antibodies, polysaccharides, and other biomolecules for sensor applications. Unusually large sizes of interconnected pores allow large target molecules to pass rapidly into and through the gel and bind to immobilized biomolecules. Sugar-containing hydrogels have extremely low non-specific absorption of labeled target molecules, providing low background levels. Some hydrogel materials do not have this type of homogeneous interconnected macroporosity, thus large target molecules cannot readily diffuse through them. Additionally, they nearly always experience non-specific absorption of labeled target molecules, limiting their usefulness in sensor applications. A method is provided for preparing sugar polyacrylate hydrogels with functional chemical groups which covalently bond oligonucleotides and peptides.Type: GrantFiled: May 19, 2006Date of Patent: August 31, 2010Assignee: The United States of America as represented by the Secretary of the NavyInventors: Mark S. Spector, David A. Stenger, Charles H. Patterson, Jr., Brett D. Martin, Paul T. Charles
-
Publication number: 20100112643Abstract: A method of: providing a solid surface having a dendrimer molecule bound thereto and a single-stranded probe nucleic acid immobilized to the dendrimer; contacting the solid surface with a sample suspected or known to contain a target ribonucleic acid; denaturing the target ribonucleic acid; and incubating the sample to allow hybridization of the denatured ribonucleic acid to the probe nucleic acids. The target ribonucleic acid is complementary to the probe nucleic acid.Type: ApplicationFiled: November 4, 2008Publication date: May 6, 2010Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Marie J. Archer, Baochuan Lin, David A. Stenger
-
Patent number: 7695941Abstract: A PCR method involving: providing a biological sample suspected of containing one or more pathogen nucleic acids; adding a plurality of PCR primers corresponding to genes found in the pathogens; and performing a polymerase chain reaction on the sample to amplify a subset of the nucleic acids that correspond to the genes. The primers include at least one primer pair for each pathogen, and the primers contain a tail sequence that is not homologous any pathogen DNA or to any background DNA in the sample. The concentration of at least one primer in the polymerase chain reaction is no more than about 100 nM.Type: GrantFiled: June 6, 2006Date of Patent: April 13, 2010Assignee: The United States of America as represented by the Secretary of the NavyInventors: Baochuan Lin, Kate M. Blaney, Anthony P. Malanoski, Joel M Schnur, David A Stenger