Patents by Inventor David Amantini

David Amantini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Patent number: 8153623
    Abstract: Compounds of formula (I), pharmaceutical compositions thereof, and methods for treatment using the same.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: April 10, 2012
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: Giuseppe Alvaro, David Amantini, Markus Bergauer, Francesca Bonetti, Roberto Profeta
  • Heteroaryl derivatives of N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-amine
    Patent number: 8133908
    Abstract: Disclosed are N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives having the following formula: wherein m, n, Het, R1, R2 and R3 are as defined herein, and their use as orexin antagonists.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: March 13, 2012
    Assignee: Glaxo Group Limited
    Inventors: Giuseppe Alvaro, David Amantini, Emiliano Castiglioni, Romano Di Fabio, Francesca Pavone
  • Imidazo[1,2-a]pyrazines as orexin receptor antagonists
    Patent number: 8129384
    Abstract: This invention relates to imidazopyrazine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: March 6, 2012
    Assignee: Glaxo Group Limited
    Inventors: Giuseppe Alvaro, David Amantini, Sandro Belvedere
  • 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS
    Publication number: 20120040991
    Abstract: Disclosed are 3-azabicyclo[4.1.0]heptane derivatives of formula (I) and their use as orexin receptor antagonists.
    Type: Application
    Filed: April 23, 2010
    Publication date: February 16, 2012
    Applicant: Glaxo Group Limited
    Inventors: David Amantini, Romano Di Fabio, Massimo Gianotti, Francesca Pavone, Francesco Ferroni
  • Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
    Patent number: 8093255
    Abstract: This invention relates to imidazopyrimidine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: January 10, 2012
    Assignee: Glaxo Group Limited
    Inventors: Giuseppe Alvaro, David Amantini, Sandro Belvedere
  • NOVEL COMPOUNDS
    Publication number: 20110288098
    Abstract: This invention relates to imidazopyrazine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Application
    Filed: August 2, 2011
    Publication date: November 24, 2011
    Inventors: Giuseppe ALVARO, David Amantini, Sandro Belvedere
  • PIPERIDINE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS
    Publication number: 20110257198
    Abstract: Disclosed are imidazopyridylmethylene substituted piperidine derivatives of Formula (I): useful as orexin antagonists.
    Type: Application
    Filed: December 21, 2009
    Publication date: October 20, 2011
    Inventors: Giuseppe Alvaro, David Amantini
  • PYRIDINE DERIVATIVES USED TO TREAT OREXIN RELATED DISORDERS
    Publication number: 20110053979
    Abstract: This invention relates to pyridinamine methyl substituted piperidinyl derivatives I and their use as pharmaceuticals.
    Type: Application
    Filed: April 8, 2009
    Publication date: March 3, 2011
    Inventors: Giuseppe Alvaro, David Amantini, Luigi Piero Stasi
  • NOVEL COMPOUNDS
    Publication number: 20100324022
    Abstract: Compounds of formula (I), pharmaceutical compositions thereof, and methods for treatment using the same.
    Type: Application
    Filed: August 4, 2010
    Publication date: December 23, 2010
    Applicant: GLAXO GROUP LIMITED
    Inventors: Giuseppe Alvaro, David Amantini, Markus Bergauer, Francesca Bonetti, Roberto Profeta
  • NOVEL COMPOUNDS
    Publication number: 20100267730
    Abstract: This invention relates to imidazopyridazine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Application
    Filed: October 9, 2009
    Publication date: October 21, 2010
    Inventors: Giuseppe ALVARO, David Amantini, Sandro Belvedere
  • Compounds
    Patent number: 7803833
    Abstract: The invention relates to quaternary ?-aminocarboxyamide derivatives of formula (I), wherein R1, R2, R3, R4, R5, R6, X, q and n are as defined in claim 1, for treating diseases and conditions mediated by modulation of voltage-gated sodium channels.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: September 28, 2010
    Assignee: Glaxo Group Limited
    Inventors: Giuseppe Alvaro, David Amantini, Markus Bergauer, Francesca Bonetti, Roberto Profeta
  • IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20100210667
    Abstract: Disclosed are imidazo[1,2-c]pyrimidin-2-ylmethyl substituted piperidine derivatives having the formula: where Ar is and where R1, R2, R3, n, p and q are as defined herein, and their use as pharmaceuticals.
    Type: Application
    Filed: July 1, 2008
    Publication date: August 19, 2010
    Inventors: Giuseppe Alvaro, David Amantini, Sandro Belvedere
  • NOVEL COMPOUNDS
    Publication number: 20100168131
    Abstract: Disclosed are N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo [4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives and their use as pharmaceuticals.
    Type: Application
    Filed: November 30, 2009
    Publication date: July 1, 2010
    Inventors: Giuseppe Alvaro, David Amantini, Emiliano Castiglioni, Romano Di Fabio, Francesca Pavone
  • NOVEL COMPOUNDS
    Publication number: 20100160345
    Abstract: This invention relates to imidazopyrazine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Application
    Filed: October 9, 2009
    Publication date: June 24, 2010
    Inventors: Giuseppe Alvaro, David Amantini, Sandro Belvedere
  • NOVEL COMPOUNDS
    Publication number: 20100160344
    Abstract: This invention relates to imidazopyrimidine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Application
    Filed: October 9, 2009
    Publication date: June 24, 2010
    Inventors: Giuseppe ALVARO, David Amantini, Sandro Belvedere
  • NOVEL COMPOUNDS
    Publication number: 20100144760
    Abstract: Disclosed are N-{[(1R,4S,6R)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives and their use as pharmaceuticals.
    Type: Application
    Filed: November 30, 2009
    Publication date: June 10, 2010
    Inventors: Giuseppe ALVARO, David Amantini, Emiliano Castiglioni, Romano Di Fabio, Francesca Pavone
  • NOVEL COMPOUNDS
    Publication number: 20090022670
    Abstract: Disclosed are imidazo[1,2-a]pyridin-2-ylmethyl substituted piperidine derivatives of formula (I) and their use as pharmaceuticals.
    Type: Application
    Filed: July 1, 2008
    Publication date: January 22, 2009
    Inventors: GIUSEPPE ALVARO, DAVID AMANTINI, SANDRO BELVEDERE
  • Novel Compounds
    Publication number: 20080293753
    Abstract: The invention relates to quaternary ?-aminocarboxyamide derivatives of formula (I), wherein R1, R2, R3, R4, R5, R6, X, q and n are as defined in claim 1, for treating diseases and conditions mediated by modulation of voltage-gated sodium channels.
    Type: Application
    Filed: October 6, 2006
    Publication date: November 27, 2008
    Inventors: Giuseppe Alvaro, David Amantini, Markus Bergauer, Francesca Bonetti, Roberto Profeta