Patents by Inventor David C. Dorn

David C. Dorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Migrastatin analogs in the treatment of cancer
    Patent number: 8957056
    Abstract: In one aspect, the present invention provides a method for treating colon and/or ovarian cancer in a subject comprising administering to a subject in need thereof a compound of general formula (I): wherein R1-R6, R, -R, Q, Y1, Y2 and n are as defined herein, wherein the compound is present in an amount effective to inhibit colon and/or ovarian tumor metastasis.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: February 17, 2015
    Assignee: Sloan-Kettering Instiute for Cancer Research
    Inventors: Samuel J. Danishefsky, Christoph Gaul, Jón T. Njardarson, Malcolm A. S. Moore, Kaida Wu, David C. Dorn, Mihirbaran Mandal
  • Isomigrastatin analogs in the treatment of cancer
    Patent number: 8188141
    Abstract: The present invention provides compounds having formula (I): (I) wherein n, R1-R5, Ra-Rb, Q, Y1 and Y2 are as defined herein; and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving increased angiogenesis.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: May 29, 2012
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Mihirbaran Mandal, David C. Dorn, Malcolm A. S. Moore
  • Migrastatin analogs in the treatment of cancer
    Publication number: 20090124662
    Abstract: In one aspect, the present invention provides a method for treating colon and/or ovarian cancer in a subject comprising administering to a subject in need thereof a compound of general formula (I): wherein R1-R6, R, -R, Q, Y1, Y2 and n are as defined herein, wherein the compound is present in an amount effective to inhibit colon and/or ovarian tumor metastasis.
    Type: Application
    Filed: May 25, 2006
    Publication date: May 14, 2009
    Inventors: Samuel J. Danishefsky, Christoph Gaul, Jon T. Njardarson, Malcolm A.S. Moore, Kaida Wu, David C. Dorn, Mihirbaran Mandal
  • Isomigrastatin Analogs In The Treatment Of Cancer
    Publication number: 20090054488
    Abstract: The present invention provides compounds having formula (I): (I) wherein n, R1-R5, Ra-Rb, Q, Y1 and Y2 are as defined herein; and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving increased angiogenesis.
    Type: Application
    Filed: September 23, 2005
    Publication date: February 26, 2009
    Inventors: Samuel J. Danishefsky, Mihirbaran Mandal, David C. Dorn, Malcolm A.S. Moore