Patents by Inventor David Deniaud

David Deniaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190388557
    Abstract: The invention is directed to the field of gene therapy, i.e. gene delivery into target cells, tissue, organ and organism, and more particularly to gene delivery via viral vectors. The inventors showed that it is possible by chemical coupling to modulate the coupling of a ligand in the surface of the capsid of AAV, for example AAV2 and AAV3b. In particular, the present invention relates to a recombinant Adeno-Associated Virus (rAAV) vector particle having at least one primary amino group contained in the capsid proteins, chemically coupled with at least one ligand L, wherein coupling of said ligand L is implemented through a bond comprising a —CSNH— bond and an optionally substituted aromatic moiety. Particularly, the inventors tested the chemical coupling of mannose ligand on AAV2 for subretinally injection to rats.
    Type: Application
    Filed: June 9, 2017
    Publication date: December 26, 2019
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE DE NANTES, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
    Inventors: Mathieu MEVEL, David DENIAUD, Eduard AYUSO
  • Patent number: 10273313
    Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia coli infections.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: April 30, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, UNIVERSITE DE PICARDIE JULES VERNE, UNIVERSITE LILLE 1-SCIENCES ET TECHNOLOGIES, UNIVERSITE D'AUVERGNE
    Inventors: Julie Bouckaert, Sebastien Gouin, David Deniaud, Rostyslav Bilyy, Tetiana Dumych, Adeline Sivignon, Arlette Darfeuille-Michaud
  • Publication number: 20150210781
    Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia Coli infections.
    Type: Application
    Filed: July 24, 2013
    Publication date: July 30, 2015
    Inventors: Julie Bouckaert, Sebastien Gouin, David Deniaud, Rostyslav Bilyy, Tetiana Dumych, Adeline Sivignon, Arlette Darfeuille-Michaud
  • Publication number: 20140364454
    Abstract: The invention relates to metal-chelating compounds comprising one or more 8-hydroxyquinoline units substituted in position 2 with a nitrogenous group comprising a polyamino chain, wherein the polyamino chain is N-substituted on said nitrogenous group, to the composition containing same, and to the uses thereof in the therapeutic field and in particular in the treatment of diseases associated with an abnormality in the regulation of metal metabolism resulting in a metal overload in human or animal cells.
    Type: Application
    Filed: December 18, 2012
    Publication date: December 11, 2014
    Inventors: Francois Gaboriau, David Deniaud, Vincent Corce, Karine Julienne Aphecetche, Eric Renault