Patents by Inventor David F. Cauble

David F. Cauble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8293747
    Abstract: The present invention relates to novel heterocyclic amide compounds of Formula I: as disclosed herein or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are compositions comprising said compounds, and methods for using said compounds for treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodegenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: October 23, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Panduranga Adulla P. Reddy, Lianyun Zhao, Praveen K. Tadikonda, Tzu Tshin Wong, Shuyi Tang, Luis E. Torres, David F. Cauble, Jr., Timothy J. Guzi, M. Arshad Siddiqui
  • Publication number: 20110129440
    Abstract: The present invention relates to novel Heterocyclic Urea and Thiourea Derivatives of formula (I), compositions comprising the Heterocyclic Urea and Thiourea Derivatives, and methods for using the Heterocyclic Urea and Thiourea Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral infection, a fungal infection, or a disorder related to the activity of a protein kinase.
    Type: Application
    Filed: October 27, 2008
    Publication date: June 2, 2011
    Inventors: Praveen K. Tadikonda, David F. Cauble, Timothy J. Guzi, M. Arshad Siddiqui
  • Publication number: 20100286135
    Abstract: The present invention relates to novel heterocyclic amide compounds of Formula I: as disclosed herein or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are compositions comprising said compounds, and methods for using said compounds for treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodegenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease.
    Type: Application
    Filed: July 17, 2008
    Publication date: November 11, 2010
    Applicant: Schering Corporation Patent Department, K-6-1; 1990
    Inventors: Panduranga Adulla P. Reddy, Lianyun Zhao, Praveen k. Tadikonda, Tzu Tshin Wong, Shuyi Tang, Luis E. Torres, David F. Cauble, JR., Timothy J. Guzi, M. Arshad Siddiqui
  • Patent number: 6491730
    Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide. The article includes a stained portion or region, which is pretreated with a pretreatment composition prior to initiating the cleaning cycle. The pretreatment step is followed by contacting the pretreated article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the article. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, a surfactant, and an organic co-solvent. After the contacting step, the article is separated from the liquid dry cleaning composition. The pretreatment composition, in a preferred embodiment, comprises at least one of (a) a surfactant; (b) d-limonene, and (c) a C12-C15 alkane co-solvent. Preferably the pretreatment composition comprises at least two, and in some particularly preferred embodiments, the pretreatment composition comprises all three, of the aforesaid ingredients.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: December 10, 2002
    Assignee: Micell Technologies, Inc.
    Inventors: David F. Cauble, Jr., James P. DeYoung, James B. McClain, Bernadette Storey-Laubach
  • Patent number: 6258766
    Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide comprises contacting an article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the fabric. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, a surfactant, and an organic co-solvent. After the contacting step, the article is separated from the liquid dry cleaning composition. The method is preferably carried out at ambient temperature. The surfactant is preferably one that does not contain a CO2-philic group. The organic co-solvent is preferably an alkane and has a flash point above 140° F.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: July 10, 2001
    Assignee: MiCell Technologies, Inc.
    Inventors: Timothy J. Romack, David F. Cauble, James B. McClain
  • Patent number: 6218353
    Abstract: A liquid composition useful for suspending and dispensing a solid particulate comprises carbon dioxide, a surfactant, an organic co-solvent, and the solid particulate to be suspended. The composition may optionally contain water. The composition is useful as a propellant in an aerosol container for spraying the solid particulate from the container.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: April 17, 2001
    Assignee: MiCell Technologies, Inc.
    Inventors: Timothy J. Romack, David F. Cauble, Jr., James B. McClain
  • Patent number: 6200352
    Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide comprises contacting an article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the fabric. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, a surfactant, and an organic co-solvent. After the contacting step, the article is separated from the liquid dry cleaning composition. The method is preferably carried out at ambient temperature. The surfactant is preferably one that does not contain a CO2-philic group. The organic co-solvent is preferably an alkane and has a flash point above 140° F.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: March 13, 2001
    Assignee: MiCell Technologies, Inc.
    Inventors: Timothy J. Romack, David F. Cauble, James B. McClain
  • Patent number: 5858022
    Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide comprises contacting an article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the fabric. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, water, a surfactant, and an organic co-solvent. After the contacting step, the article is separated from the liquid dry cleaning composition. The method is preferably carried out at ambient temperature. The surfactant may be either one that contains a CO.sub.2 -philic group or one that does not contain a CO.sub.2 -philic group. The organic co-solvent is preferably an alkane that has a flash point above 140.degree. F.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: January 12, 1999
    Assignee: MiCell Technologies, Inc.
    Inventors: Timothy J. Romack, David F. Cauble, James B. McClain