Patents by Inventor David Garcia

David Garcia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11198861
    Abstract: The present invention provides engineered phenylalanine ammonia lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia lyase (PAL) polypeptides. Methods for producing PAL enzymes are also provided. In some embodiments, the engineered PAL polypeptides are optimized to provide enhanced catalytic activities that are useful under industrial process conditions for the production of pharmaceutical compounds.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: December 14, 2021
    Assignee: Codexis, Inc.
    Inventors: Scott J. Novick, Ravi David Garcia, Charlene Ching, Nikki Dellas, David Entwistle, Vesna Mitchell
  • Publication number: 20210360468
    Abstract: Systems and methods for balancing load in an area of a wireless network comprising first nodes operating according to a first Radio Access Technology and at least one second node operating according to a second Radio Access Technology. The method comprises establishing a connection between a user device and a first node; receiving an indication of an entry threshold for establishing a connection between the user device and a second node during a current time period, wherein the entry threshold is determined in dependence on an expected usage requirement for the area of the wireless network during the current time period; determining, by the user device, whether a parameter of a signal received from the second node exceeds the entry threshold; and responsive to determining that the parameter of the signal received from the second node exceeds the entry threshold, establishing, by the first node, a dual connectivity session between the user device and both the first and the second nodes.
    Type: Application
    Filed: May 13, 2021
    Publication date: November 18, 2021
    Inventors: Marc Nieto Aliques, David García Roger, Daniel Calabuig Soler, Pau Usach Molina, María Victoria Bausá Aragonés, Francisco Vicente Guillén Ruiz, Eduardo Palomero Lopez
  • Publication number: 20210324425
    Abstract: The present disclosure is directed to methods for proteome engineering cells such that cell-free extracts prepared from such engineered cells can be modified to have metabolic flux directed to a metabolism of interest. In addition, methods for producing cell-free extracts with directed metabolism, cell-free extracts and kits that contain cell-free extracts are also disclosed.
    Type: Application
    Filed: April 20, 2021
    Publication date: October 21, 2021
    Inventors: Mitchel J. Doktycz, Jaime Lorenzo N Dinglasan, David Garcia, Ben P. Mohr
  • Publication number: 20210140146
    Abstract: A training machine to generate training data for supervised machine learning. The training machine is a working machine with a camera, a sensor, a body, and a moveable element moveable relative to the body. Training data is generated by capturing images, using the camera of at least a portion of the moveable element; and determining, using the sensor, sensor data which indicates the position of the moveable element in the image. The training data is used to train a machine learning algorithm to determine a position of a moveable element based on an image of at least a portion of the moveable element, without the need for corresponding sensor data.
    Type: Application
    Filed: May 4, 2018
    Publication date: May 13, 2021
    Applicant: J.C. BAMFORD EXCAVATORS LIMITED
    Inventors: David Garcia Corrochano, Paul Smallman
  • Publication number: 20210106355
    Abstract: A medical device for the insertion of a tube, with which a tube is introduced from the oral or nasal cavity to the oesophagus of a patient. The device includes tubing and an inlet body, the inlet body is adapted to be arranged between the posterior pharynx and the upper third of the oesophagus of a patient, and the inlet body is joined to the tubing at a point along the vertical dimension thereof; the tubing and the inlet body also being in connection through a through hole which communicates them internally.
    Type: Application
    Filed: July 7, 2020
    Publication date: April 15, 2021
    Inventor: Manuel David GARCÍA ANDRES
  • Publication number: 20210034332
    Abstract: Many computing systems process data organized in a matrix format. For example, artificial neural networks (ANNs) perform numerous computations on data organized into matrices using conventional matrix arithmetic operations. One such operation, which is commonly performed, is the transpose operation. Additionally, many such systems need to process many matrices and/or matrices that are large in size. For sparse matrices that hold few significant values and many values that can be ignored, transmitting and processing all the values in such matrices is wasteful. Thus, techniques are introduced for storing a sparse matrix in a compressed format that allows for a matrix transpose operation to be performed on the compressed matrix without having to first decompress the compressed matrix. By utilizing the introduced techniques, more matrix operations can be performed than conventional systems.
    Type: Application
    Filed: October 19, 2020
    Publication date: February 4, 2021
    Inventors: Jorge Albericio Latorre, Jeff Pool, David Garcia
  • Publication number: 20210032605
    Abstract: The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
    Type: Application
    Filed: October 16, 2020
    Publication date: February 4, 2021
    Inventors: Jovana Nazor, Robert Osborne, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle, Rama Voladri, Ravi David Garcia, Jeffrey C. Moore, Shane Grosser, Birgit Kosjek, Matthew Truppo
  • Patent number: 10860293
    Abstract: Many computing systems process data organized in a matrix format. For example, artificial neural networks (ANNs) perform numerous computations on data organized into matrices using conventional matrix arithmetic operations. One such operation, which is commonly performed, is the transpose operation. Additionally, many such systems need to process many matrices and/or matrices that are large in size. For sparse matrices that hold few significant values and many values that can be ignored, transmitting and processing all the values in such matrices is wasteful. Thus, techniques are introduced for storing a sparse matrix in a compressed format that allows for a matrix transpose operation to be performed on the compressed matrix without having to first decompress the compressed matrix. By utilizing the introduced techniques, more matrix operations can be performed than conventional systems.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: December 8, 2020
    Assignee: Nvidia Corporation
    Inventors: Jorge Albericio Latorre, Jeff Pool, David Garcia
  • Patent number: 10844358
    Abstract: The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 24, 2020
    Assignee: Codexis, Inc.
    Inventors: Jovana Nazor, Robert Osborne, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle, Rama Voladri, Ravi David Garcia, Jeffrey C. Moore, Shane Grosser, Birgit Kosjek, Matthew Truppo
  • Publication number: 20200339972
    Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
    Type: Application
    Filed: June 15, 2020
    Publication date: October 29, 2020
    Inventors: Jovana Nazor, Vesna Mitchell, David Elgart, Katrina W. Lexa, Nikki Dellas, Robert Kevin Orr, Oscar Alvizo, Ravi David Garcia, Judy Victoria Antonio Viduya, Courtney Dianne Moffett
  • Publication number: 20200318040
    Abstract: The invention relates to a system for the propagation of yeast and adaptation to ethanol in a sustained manner using a bioreactor (1) which is programmed automatically and in which the propagation and adaptation to ethanol, pH and temperature is carried out, for a secondary fermentation in the tirage of Cava, Champagne and sparkling wines in general. The bioreactor (1) includes a motor (6) with stirring blades, and a temperature-control system comprising a sleeve and an electrical resistor, said bioreactor (1) being associated with a mixing tank (2) which houses the liquor. In addition, a programmed pump (4) is provided between the bioreactor (1) and the mixing tank (2), as well as a programmable automaton with a control panel (5) for automating the process.
    Type: Application
    Filed: May 26, 2017
    Publication date: October 8, 2020
    Inventor: David Garcia Yoldi
  • Publication number: 20200272425
    Abstract: Many computing systems process data organized in a matrix format. For example, artificial neural networks (ANNs) perform numerous computations on data organized into matrices using conventional matrix arithmetic operations. One such operation, which is commonly performed, is the transpose operation. Additionally, many such systems need to process many matrices and/or matrices that are large in size. For sparse matrices that hold few significant values and many values that can be ignored, transmitting and processing all the values in such matrices is wasteful. Thus, techniques are introduced for storing a sparse matrix in a compressed format that allows for a matrix transpose operation to be performed on the compressed matrix without having to first decompress the compressed matrix. By utilizing the introduced techniques, more matrix operations can be performed than conventional systems.
    Type: Application
    Filed: February 27, 2019
    Publication date: August 27, 2020
    Inventors: Jorge Albericio Latorre, Jeff Pool, David Garcia
  • Patent number: 10724025
    Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: July 28, 2020
    Assignee: Codexis, Inc.
    Inventors: Jovana Nazor, Vesna Mitchell, David Elgart, Katrina W. Lexa, Nikki Dellas, Robert Kevin Orr, Oscar Alvizo, Ravi David Garcia, Judy Victoria Antonio Viduya, Courtney Dianne Moffett
  • Publication number: 20200184553
    Abstract: A system includes credit network computing device(s) coupled to wallet provider computing device(s) and credit exchange computing device(s). Wallet provider computing device(s) receives credit request for loan having credit terms from borrower; generates smart contract including information regarding borrower and credit terms; and communicates smart contract to credit network computing device(s). Credit network computing device(s) receives indication that cosigner agrees to cosign for credit request on behalf of borrower; and communicates smart contract representing credit requests to credit exchange computing device(s). Credit exchange computing device(s) places smart contract representing credit request on order book. Credit exchange computing device(s) receives trading order for smart contract representing credit request from lender.
    Type: Application
    Filed: July 5, 2018
    Publication date: June 11, 2020
    Applicant: RIPIO International SEZC
    Inventors: Sebastian Serrano, Luciana Marcela Gruszeczka, David Garcia
  • Publication number: 20200109378
    Abstract: The present invention provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The invention also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
    Type: Application
    Filed: May 23, 2018
    Publication date: April 9, 2020
    Inventors: Scott J. Novick, Nikki Dellas, Oscar Alvizo, Ravi David Garcia, Charlene Ching, David Entwistle
  • Patent number: 10610144
    Abstract: A method and system for generating a personalized health management recommendation for a user. During operation, the system obtains first physiological data generated by a wearable device worn by the user that indicates a physiological condition of the user. The system then generates a prediction model for the user based on the first physiological data. Next, the system obtains real-time physiological data generated by the wearable device. The system may generate a prediction by analyzing the real-time physiological data to determine whether the user's physiological condition exceeds a threshold parameter according to the prediction model. Upon determining that the threshold parameter has been exceeded, the system may select a recommendation and send the recommendation message to the user's mobile device.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: April 7, 2020
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Hoda M. A. Eldardiry, Jonathan Rubin, Rui Abreu, Shane P. Ahern, Daniel G. Bobrow, David Garcia, Honglu Du, Ashish Pattekar
  • Publication number: 20200082118
    Abstract: Systems, devices, and methods for controlling access to a medical device are provided. One example system includes an access card configured to wirelessly transmit user identification information and a medical device configured to receive the user identification information from the access card, and enable access to one or more components of the medical device based on permission information associated with the received user identification information. One example medical device includes a plurality of device components; a data receiver configured to wirelessly receive user identification information; a memory configured to store permission information in association with the user identification information; and a processor configured to retrieve the permission information from the memory in response to receiving the user identification information from the data receiver, and enable access to the one or more device components based on the retrieved permission information.
    Type: Application
    Filed: November 11, 2019
    Publication date: March 12, 2020
    Inventors: Angel Diaz Carmena, David Garcia Godoy, Carlos Rodriguez Gonzalez, Jose Antonio Gonzalez Romera
  • Publication number: 20200071913
    Abstract: A working machine has a body and a moveable element. The moveable element is moveable relative to the body. A camera captures an image of at least a portion of the moveable element. A processor executes a machine learning algorithm trained to determine a position of a moveable element from an image of the moveable element. The machine learning algorithm receives the image from the camera and determines the position of the moveable element in the image.
    Type: Application
    Filed: May 4, 2018
    Publication date: March 5, 2020
    Applicant: J.C. BAMFORD EXCAVATORS LIMITED
    Inventor: David Garcia Corrochano
  • Publication number: 20200032028
    Abstract: A method for manufacturing electrically conductive structures, preferably conductive pathway structures using laser beams on a non-conductive carrier (LDS method), wherein a non-conductive carrier material is provided which contains at least one inorganic metal phosphate compound and at least one stabiliser finely distributed or dissolved therein, the carrier material is irradiated in regions by laser beams generating the electrically conductive structures in the irradiated regions.
    Type: Application
    Filed: March 26, 2018
    Publication date: January 30, 2020
    Applicant: Chemische Fabrik Budenheim KG
    Inventors: Sven FÜNDERICH, David Garcia MARTINEZ, Thomas FUTTERER, Christian LITTERSCHEID, Rüdiger WISSEMBORSKI, Jorge FLORES
  • Publication number: 20200017845
    Abstract: The present invention provides engineered phenylalanine ammonia lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia lyase (PAL) polypeptides. Methods for producing PAL enzymes are also provided. In some embodiments, the engineered PAL polypeptides are optimized to provide enhanced catalytic activities that are useful under industrial process conditions for the production of pharmaceutical compounds.
    Type: Application
    Filed: June 14, 2019
    Publication date: January 16, 2020
    Inventors: Scott J. Novick, Ravi David Garcia, Charlene Ching, Nikki Dellas, David Entwistle, Vesna Mitchell