Patents by Inventor David Granville
David Granville has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11857699Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.Type: GrantFiled: December 18, 2020Date of Patent: January 2, 2024Assignee: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Publication number: 20230338618Abstract: An implantable tubular textile graft includes a water-insoluble elastomeric sealant disposed at the textile tubular wall such that the graft is impermeable to water at 120 mm Hg pressure. The inner surface of the textile tubular wall configured to promote growth of biological tissue and/or promote growth of pseudointima.Type: ApplicationFiled: October 19, 2022Publication date: October 26, 2023Applicant: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Patent number: 11666683Abstract: A medical textile product includes a textile substrate having opposed first and second surfaces with the textile substrate including a textile construction of one or more yarns. The second surface includes a coating of a substantially water-insoluble, non-porous elastomeric sealant. The one or more yarns at the first surface are pre-treated with a removable composition, such that the water-insoluble elastomeric sealant encapsulates a portion of fibers of the one or more yarns at the second surface of the textile substrate. The textile substrate is substantially impermeable to fluid. The first surface is substantially free of the substantially water-insoluble elastomeric sealant. The textile substrate may be a non-tubular substrate, such as a planar sheet, a shaped sheet, and a tape, or a tubular substrate, such as a cylindrical conduit, a tubular conduit, a Y-shaped, a T-shaped conduit, a multi-channel conduit, and a bulbous shaped conduit.Type: GrantFiled: May 5, 2021Date of Patent: June 6, 2023Assignee: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Patent number: 11577003Abstract: A method of detecting the presence or absence of a sealant applied to a textile graft includes the steps of: providing a textile graft having a first surface and an opposed second surface; providing a water soluble masking agent; applying the water soluble masking agent to at least a portion of the first surface of the textile graft; providing a sealant solution; providing a visual indicator; applying the water insoluble sealing agent and the visual indicator to the second surface of the textile graft; and removing the water soluble masking agent after the step of applying sealing solution. The second surface has visual indication of the visual indicator and the first surface is substantially free of visual indication of the visual indicator. An implantable textile graft includes the selectively applied visual indicator.Type: GrantFiled: May 5, 2021Date of Patent: February 14, 2023Assignee: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton, Lindsey Calcutt, Paul Van Hulle, James Wade Curlee
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Publication number: 20210283309Abstract: A method of detecting the presence or absence of a sealant applied to a textile graft includes the steps of: providing a textile graft having a first surface and an opposed second surface; providing a water soluble masking agent; applying the water soluble masking agent to at least a portion of the first surface of the textile graft; providing a sealant solution; providing a visual indicator; applying the water insoluble sealing agent and the visual indicator to the second surface of the textile graft; and removing the water soluble masking agent after the step of applying sealing solution. The second surface has visual indication of the visual indicator and the first surface is substantially free of visual indication of the visual indicator. An implantable textile graft includes the selectively applied visual indicator.Type: ApplicationFiled: May 5, 2021Publication date: September 16, 2021Applicant: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton, Lindsey Calcutt, Paul Van Hulle, James Wade Curlee
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Publication number: 20210283310Abstract: An implantable textile graft includes a textile tubular wall of liquid permeable textile construction of one or more yarns having opposed inner and outer surfaces. A portion of the inner surface includes a removable coating. The outer surface includes a coating of a water-insoluble, non-porous elastomeric sealant, such as a silicone-containing polymer, a polyurethane-containing polymer, and/or a polycarbonate-containing polymer, for limiting movement of fluid through the wall. The textile tubular wall is, after curing of the sealant, impermeable to water at 120 mm Hg pressure. The removable coating prevents migrating of the outer coating onto the inner surface of the textile tubular wall and the removable coating is removed prior to implantation of the graft. The portion of the inner surface of the textile tubular wall is substantially free of the water-insoluble elastomeric sealant following removal of the removable coating.Type: ApplicationFiled: May 27, 2021Publication date: September 16, 2021Applicant: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Publication number: 20210260251Abstract: A medical textile product includes a textile substrate having opposed first and second surfaces with the textile substrate including a textile construction of one or more yarns. The second surface includes a coating of a substantially water-insoluble, non-porous elastomeric sealant. The one or more yarns at the first surface are pre-treated with a removable composition, such that the water-insoluble elastomeric sealant encapsulates a portion of fibers of the one or more yarns at the second surface of the textile substrate. The textile substrate is substantially impermeable to fluid. The first surface is substantially free of the substantially water-insoluble elastomeric sealant. The textile substrate may be a non-tubular substrate, such as a planar sheet, a shaped sheet, and a tape, or a tubular substrate, such as a cylindrical conduit, a tubular conduit, a Y-shaped, a T-shaped conduit, a multi-channel conduit, and a bulbous shaped conduit.Type: ApplicationFiled: May 5, 2021Publication date: August 26, 2021Applicant: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Patent number: 11045586Abstract: A method of manufacturing a tubular graft may include the steps of: providing a textile including a tubular wall disposed between a first open end and an opposed second open end, an inner surface and an opposed outer surface defining an interior wall portion therein between, the tubular wall including a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid; applying a substantially water-soluble material to at least a portion of the tubular wall; and applying a substantially water-insoluble sealant to at least a part of the outer surface of the tubular wall, the substantially water-insoluble sealant being configured to mitigate movement of fluid through the wall of the conduit; where the water-soluble material is configured to mitigate penetration of the sealant to the inner surface of the conduit.Type: GrantFiled: October 31, 2018Date of Patent: June 29, 2021Assignee: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Patent number: 11027046Abstract: A substantially fluid impermeable textile graft may be produced by selective application of a substantially water-soluble material or masking agent, and optionally selective removal of excess substantially water-soluble material, followed by the application of a substantially water-insoluble sealant. The inner surface of the graft includes a coating of the substantially water-soluble material thereon. The outer surface includes a coating of the substantially water-insoluble sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble sealant is, after curing thereof, substantially impermeable to liquid. The substantially water-soluble material is removed from the graft after the application of the substantially water-insoluble sealant.Type: GrantFiled: May 8, 2019Date of Patent: June 8, 2021Assignee: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton, Brian McMurray, Chadd Clark, Lindsey Calcutt, Kayla Wilson, Josh Davidson
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Patent number: 11026823Abstract: A control system for deploying a stent graft including a resilient ring stent at one end, provides a delivery shaft carrying the stent graft with the ring stent adjacent a proximal end of the shaft for insertion into a lumen; a retractable sleeve for containing the stent graft on the delivery shaft; a control handle adjacent the distal end, of the delivery shaft; and stent peak and valley control wires extending from the proximal end of the delivery shaft to peak and valley controllers at the control handle. Use of the control wires effects movement and/or rotation of the graft allowing fine control of deployment in the lumen.Type: GrantFiled: November 5, 2018Date of Patent: June 8, 2021Assignee: Vascutek LimitedInventors: Gary Peter McDonald, David Granville Stevenson
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Publication number: 20210128789Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.Type: ApplicationFiled: December 18, 2020Publication date: May 6, 2021Applicant: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Patent number: 10926003Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.Type: GrantFiled: February 12, 2019Date of Patent: February 23, 2021Assignee: Hothouse Medical LimitedInventors: David Granville Stevenson, Timothy Rawden Ashton
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Publication number: 20200330213Abstract: A method of manufacturing a tubular graft may include the steps of: providing a textile including a tubular wall disposed between a first open end and an opposed second open end, an inner surface and an opposed outer surface defining an interior wall portion therein between, the tubular wall including a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid; applying a substantially water-soluble material to at least a portion of the tubular wall; and applying a substantially water-insoluble sealant to at least a part of the outer surface of the tubular wall, the substantially water-insoluble sealant being configured to mitigate movement of fluid through the wall of the conduit; where the water-soluble material is configured to mitigate penetration of the sealant to the inner surface of the conduit.Type: ApplicationFiled: October 31, 2018Publication date: October 22, 2020Inventors: David Granville Stevenson, Timothy Rawden Ashton
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Publication number: 20190307924Abstract: A substantially fluid impermeable textile graft may be produced by selective application of a substantially water-soluble material or masking agent, and optionally selective removal of excess substantially water-soluble material, followed by the application of a substantially water-insoluble sealant. The inner surface of the graft includes a coating of the substantially water-soluble material thereon. The outer surface includes a coating of the substantially water-insoluble sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble sealant is, after curing thereof, substantially impermeable to liquid. The substantially water-soluble material is removed from the graft after the application of the substantially water-insoluble sealant.Type: ApplicationFiled: May 8, 2019Publication date: October 10, 2019Inventors: David Granville Stevenson, Timothy Rawden Ashton, Brian McMurray, Chadd Clark, Lindsey Calcutt, Kayla Wilson, Josh Davidson
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Publication number: 20190175790Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: David Granville Stevenson, Timothy Rawden Ashton
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Publication number: 20190070031Abstract: A control system for deploying a stent graft including a resilient ring stent at one end, provides a delivery shaft carrying the stent graft with the ring stent adjacent a proximal end of the shaft for insertion into a lumen; a retractable sleeve for containing the stent graft on the delivery shaft; a control handle adjacent the distal end, of the delivery shaft; and stent peak and valley control wires extending from the proximal end of the delivery shaft to peak and valley controllers at the control handle. Use of the control wires effects movement and/or rotation of the graft allowing fine control of deployment in the lumen.Type: ApplicationFiled: November 5, 2018Publication date: March 7, 2019Applicant: Vascutek LimitedInventors: Gary Peter MCDONALD, David Granville STEVENSON
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Publication number: 20190038602Abstract: Formulations for treating burns and burn wound healing comprising a Granzyme B inhibitor and a pharmaceutically acceptable carrier, and methods for treating burns and for burn wound healing using the formulations.Type: ApplicationFiled: February 3, 2017Publication date: February 7, 2019Applicants: viDA Therapeutics, Inc., The University of British ColumbiaInventors: David Granville, Yue Shen, Maria Fernanda Zuluaga Estrada, Dale R. Cameron, Anthony S.K. Boey
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Patent number: 10137021Abstract: A control system for deploying a stent graft (20) including a resilient ring stent (22) at one end, provides a delivery shaft (30) carrying the stent graft with the ring stent adjacent a proximal end (33) of the shaft for insertion into a lumen; a retractable sleeve (36) for containing the stent graft on the delivery shaft; a control handle (38) adjacent the distal end (34), of the delivery shaft; and stent peak (50, 52) and valley (70, 72) control wires extending from the proximal end of the delivery shaft to peak and valley controllers (58; 74, 76) at the control handle. Use of the control wires effects movement and/or rotation of the graft allowing fine control of deployment in the lumen.Type: GrantFiled: June 1, 2012Date of Patent: November 27, 2018Assignee: VASCUTEK LIMITEDInventors: Gary Peter McDonald, David Granville Stevenson
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Patent number: 9510936Abstract: There is provided a stent element comprising a central portion with two arms extending therefrom, optionally in a V-shaped or Y-shaped configuration. The arms of the stent-element are resiliently deformable to facilitate packing and suitable material for forming the stent-element is nitinol or PEEK. The stent element can be used to stabilise two adjacent ring stents on a stent graft by attachment to the graft material between the ring stents, for example by sewing. The stent element stabilises the ring stent without risk of fracture. A stent graft having two ring stents and the stent element located between the ring stents is also described.Type: GrantFiled: June 1, 2012Date of Patent: December 6, 2016Assignee: VASCUTEK LIMITEDInventors: Gary Peter McDonald, David Granville Stevenson
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Patent number: 9398964Abstract: There is provided a device to secure a prosthesis, such as a stent graft, to the internal wall of a body lumen. The device is formed from two elongate elements each comprising a central portion with at least one arm extending therefrom. The central portions of the elements abut. Optionally, the central portions are joined together, optionally by a joining element which can act as a hinge. The terminal end of each arm can be shaped for engagement with the inner surface of the body lumen. The device is reversibly interchangeable between a first folded configuration and a second deployed or open configuration. The device is preferably attached to the sleeve of a stent graft independent of the stents which are preferably ring stents. A stent graft comprising the device is also described.Type: GrantFiled: June 1, 2012Date of Patent: July 26, 2016Assignee: VASCUTEK LIMITEDInventors: Graham McGee, David Granville Stevenson