Patents by Inventor David H. Chantry

David H. Chantry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances, and uses thereof
    Patent number: 7018627
    Abstract: The present invention provides purified and isolated polynucleotide sequences encoding a novel macrophage-derived C—C chemokine designated “Macrophage Derived Chemokine” (MDC), and polypeptide fragments and analogs thereof. Also provided are materials and methods for the recombinant or synthetic production of the chemokine, fragments, and analogs; and purified and isolated chemokine protein, and polypeptide fragments and analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing. Also provided are assays for identifying modulators of MDC chemokine activity.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: March 28, 2006
    Assignee: Icos Corporation
    Inventors: Patrick W. Gray, David H. Chantry, Michael C. Deeley, Carol J. Raport, Ronald Godiska
  • Macrophage derived chemokine (MDC) and chemokine analogs and assay to identify modulators of MDC activity, and therapeutic uses for same
    Patent number: 6737513
    Abstract: The present invention provides purified and isolated polynucleotide sequences encoding a novel human macrophage-derived C-C chemokine designated Macrophage Derived Chemokine (MDC), and polypeptide analogs thereof Also provided are materials and methods for the recombinant production of the chemokine, and purified and isolated chemokine protein, and polypeptide analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: May 18, 2004
    Assignee: ICOS Corporation
    Inventors: Patrick W. Gray, David H. Chantry, Michael C. Deeley
  • Lipid kinase
    Patent number: 5985589
    Abstract: The present invention generally relates to a novel catalytic subunit of a lipid kinase designated p110.delta.. Polynucleotides encoding p110.delta. and recombinant p110.delta. polypeptides are provided along with antibodies to p110.delta., assays for identifying inhibitors of p110.delta., and the like.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: November 16, 1999
    Assignee: ICOS Corporation
    Inventors: David H. Chantry, Merl F. Hoekstra, Douglas A. Holtzman
  • Lipid kinase
    Patent number: 5882910
    Abstract: The present invention generally relates to a novel catalytic subunit of a lipid kinase designated p110.delta.. Polynucleotides encoding p110.delta. and recombinant p110.delta. polypeptides are provided along with antibodies to p110.delta., assays for identifying inhibitors of p110.delta., and the like.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 16, 1999
    Assignee: ICOS Corporation
    Inventors: David H. Chantry, Merl F. Hoekstra, Douglas A. Holtzman
  • Lipid kinase
    Patent number: 5858753
    Abstract: The present invention generally relates to a novel catalytic subunit of a lipid kinase designated p110.delta.. Polynucleotides encoding p110.delta. and recombinant p110.delta. polypeptides are provided along with antibodies to p110.delta., assays for identifying inhibitors of p110.delta., and the like.
    Type: Grant
    Filed: November 25, 1996
    Date of Patent: January 12, 1999
    Assignee: ICOS Corporation
    Inventors: David H. Chantry, Merl F. Hoekstra, Douglas A. Holtzman