Abstract: Interlacing equipment may be used to form fabric and to create a gap in the fabric. The fabric may include one or more conductive strands. An insertion tool may be used to align an electrical component with the conductive strands during interlacing operations. A soldering tool may be used to remove insulation from the conductive strands to expose conductive segments on the conductive strands. The soldering tool may be used to solder the conductive segments to the electrical component. The solder connections may be located in grooves in the electrical component. An encapsulation tool may dispense encapsulation material in the grooves to encapsulate the solder connections. After the electrical component is electrically connected to the conductive strands, the insertion tool may position and release the electrical component in the gap. A component retention tool may temporarily be used to retain the electrical component in the gap as interlacing operations continue.

Abstract: Interlacing equipment may be used to form fabric and to create a gap in the fabric. The fabric may include one or more conductive strands. An insertion tool may be used to align an electrical component with the conductive strands during interlacing operations. A soldering tool may be used to remove insulation from the conductive strands to expose conductive segments on the conductive strands. The soldering tool may be used to solder the conductive segments to the electrical component. The solder connections may be located in grooves in the electrical component. An encapsulation tool may dispense encapsulation material in the grooves to encapsulate the solder connections. After the electrical component is electrically connected to the conductive strands, the insertion tool may position and release the electrical component in the gap. A component retention tool may temporarily be used to retain the electrical component in the gap as interlacing operations continue.

Abstract: A system for managing a value chain includes a planning application that receives planning data from a number of entities included in a value chain and automatically generates a plan according to the planning data. At least two of the entities do not directly communicate planning data to one another. The system also includes a manager application that receives the plan and automatically identifies one or more exceptions in the plan, communicates planning data relating to the exceptions to one or more of the entities, receives instructions from one or more of the entities regarding how the exceptions are to resolved, and automatically modifies the planning data in response to the instructions.

Abstract: A system (10) for managing a value chain includes a planning application (36) that receives planning data from a number of entities included in a value chain and automatically generates a plan according to the planning data. At least two of the entities do not directly communicate planning data to one another. The system (10) also includes a manager application (44) that receives the plan and automatically identifies one or more exceptions in the plan, communicates planning data relating to the exceptions to one or more of the entities, receives instructions from one or more of the entities regarding how the exceptions are to resolved, and automatically modifies the planning data in response to the instructions.

Abstract: A system (10) for managing a value chain includes a planning application (36) that receives planning data from a number of entities included in a value chain and automatically generates a plan according to the planning data. At least two of the entities do not directly communicate planning data to one another. The system (10) also includes a manager application (44) that receives the plan and automatically identifies one or more exceptions in the plan, communicates planning data relating to the exceptions to one or more of the entities, receives instructions from one or more of the entities regarding how the exceptions are to resolved, and automatically modifies the planning data in response to the instructions.

Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.

Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermatological condition.

Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.

Abstract: A transom saver and transom saver buddy for use in connection with water craft provided with an outboard motor or stern drive apparatus including transom saver structure having an elongated member adapted to be secured at one end to a trailer for the craft and at the other end to engage the motor or stern drive shank and provided with bracket structure adapted to be secured to the trailer and receive for temporary storage the elongated member which is bent to form an obtuse angle.

Abstract: A transom saver and transom saver buddy for use in connection with water craft provided with an outboard motor or stern drive apparatus including transom saver structure having an elongated member adapted to be secured at one end to a trailer for the craft and at the other end to engage the motor or stern drive shank and provided with bracket structure adapted to be secured to the trailer and receive for temporary storage the elongated member which is bent to form an obtuse angle.

Abstract: Apparatus and electrical circuitry are provided for electrical devices in order to provide electrical isolation of exposed electrical contacts on at least one of multiple modules of the electrical device. The apparatus includes at least one actuating component in one module and at least one sensor component within a second module in electrical communication with electrical circuitry, whereby electrical isolation of the exposed electrical contacts ceases when the sensor apparatus senses a desired location of the module. Placement of the apparatus and electrical circuitry to reside within the modules promotes electrical safety while minimizing tampering with safety aspects of the device. The apparatus and circuitry are useful for medical devices such as handheld diagnostic devices and consumer devices such as telephones.

Abstract: Apparatus and electrical circuitry are provided for electrical devices in order to provide electrical isolation of exposed electrical contacts on at least one of multiple modules of the electrical device. The apparatus includes at least one actuating component in one module and at least one sensor component within a second module in electrical communication with electrical circuitry, whereby electrical isolation of the exposed electrical contacts ceases when the sensor apparatus senses a desired location of the module. Placement of the apparatus and electrical circuitry to reside within the modules promotes electrical safety while minimizing tampering with safety aspects of the device. The apparatus and circuitry are useful for medical devices such as handheld diagnostic devices and consumer devices such as telephones.

Abstract: Apparatus and electrical circuitry are provided for electrical devices in order to provide electrical isolation of exposed electrical contacts on at least one of multiple modules of the electrical device. The apparatus includes at least one actuating component in one module and at least one sensor component within a second module in electrical communication with electrical circuitry, whereby electrical isolation of the exposed electrical contacts ceases when the sensor apparatus senses a desired location of the module. Placement of the apparatus and electrical circuitry to reside within the modules promotes electrical safety while minimizing tampering with safety aspects of the device. The apparatus and circuitry are useful for medical devices such as handheld diagnostic devices and consumer devices such as telephones.

Abstract: A housing assembly for electronic circuitry that can be used subcutaneously. The housing assembly comprises container and base subassemblies each comprising a ceramic portion and a continuous metal sealing flange having a first portion brazed to the ceramic portion around its periphery, and a second portion spaced from the ceramic portion. The ceramic portion of the container subassembly is dish-like to define a cavity, and has a plurality of electric leads brazed to and extending through it. Electronic components are placed in the cavity and attached to the leads, after which the sealing flanges are nested together and welded together along the distal edges of their second portions to close and seal the housing assembly.

Abstract: An implantable demand-inhibit type cardiac pacer for producing artificial stimulating pulses of a desired repetition rate and of a desired pulse width in the absence of normal R-wave activity in the patient's heart. The pacer is implemented principally from integrated circuit digital logic components and includes programmable registers, which when addressed by an externally applied code word of a predetermined format, allows the pulse width as well as the pulse rate of the pacer pulses to be changed to different desired values. Also incorporated in the pacer of this invention is circuitry which allows testing of the implanted energy source so that a physician can readily determine whether the energy source has discharged to a point where replacement is indicated.A dual refractory period for paced beats and normal beats is provided along with digital circuits for insuring proper operation even in the presence of extraneous noise signals.

Abstract: An improved contact lens and method of forming the same which causes the lens to adopt and maintain a particular angular orientation upon the eye of a wearer. One or more characters are formed in relief upon a surface of the lens at a point which is intended as the topmost point in the lens when properly oriented. The relieved characters may be used alone or in combination with previously-known means for effecting orientation of the lens.

Abstract: A system and a process for producing methane gas by anaerobic digestion of feed materials containing suitable organic materials. The system includes a plurality of digestion modules arranged primarily in series. Each digestion module is positioned with its slurry inlet port at a slightly lower elevation than the slurry outlet port of the preceding digestion module. The number of digestion modules is dependent upon the particular feed material to be digested. Each digestion module can be sampled and controlled independently. The process includes grinding and pulping the feed material, mixing the feed material with a liquid to prepare a slurry, charging the initial digestion module with slurry and transferring the digesting slurry to the next successive digestion module and subsequently to each successive digestion module after predetermined time periods until the digestion process has been completed. The liquid is separated from the digested slurry for recycle through the system.

Abstract: A compact vertical array of concentrically stacked and interfaced anaerobic digestion modules which comprise an anaerobic digestion sub-system. Each individual digestion module is an open-ended reaction vessel having an external flange on each end. Each pair of adjacent reaction vessels has a suitably sloped plate positioned at their interface and fastened to the bottom flange of the upper vessel and the top flange of the lower vessel. In this manner, each plate creates two individual digestion modules by serving as a bottom for the reaction vessel immediately above it and as a top for the reaction vessel immediately below it. Suitable openings are provided between adjacent digestion modules for transfer of digesting slurry from the module above to the module below. Each such opening is provided with a suitable valve for closing the opening during normal anaerobic digestion operations.

Abstract: Indicia are formed in the surface of an ophthalmic contact lens by sublimating lens material with a high intensity beam of radiation. A beam of light from a laser is directed through one or more cooperating masks having openings defining desired indicia. The light which passes through the masks is directed upon a surface of a contact lens, advantageously near the periphery thereof. By selecting a proper wavelength and controlling the amount of energy directed upon the lens surface the depth of sublimation of lens material can be controlled. In this manner symbols can be formed upon the lens for uniquely identifying it.

Abstract: Disclosed is a radio capsule having an electrode structure for measuring the concentration of an ionic species in an ion containing solution. A thin film conductive electrode is strongly bonded to the inner surface of a thin cylindrically shaped membrane of glass sensitive to the ionic species. A conductive lead wire makes electrical contact with the electrode. A mass of non-conductive reinforcing backing material having a thermal coefficient of expansion greater than that of the membrane strongly adheres to the conductive electrode and the membrane. The backing material is cured or solidified at a temperature sufficiently higher than that at which the electrode structure is to be used so that contraction of the backing material during curing places the membrane in a state of compression, thereby strengthening the same.