Patents by Inventor David John Hughes

David John Hughes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10570115
    Abstract: Compounds of Formula I: pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 25, 2020
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Timothy Alcacio, Minson Baek, Peter Grootenhuis, Sara Sabina Hadida Ruah, Robert M. Hughes, Ali Keshavarz-Shokri, Rachel McAuley-Aoki, Jason McCartney, Mark Thomas Miller, Fredrick Van Goor, Beili Zhang, Corey Anderson, Thomas Cleveland, Bryan A. Frieman, Haripada Khatuya, Pramod Virupax Joshi, Paul John Krenitsky, Vito Melillo, Fabrice Jean Denis Pierre, Andreas P. Termin, Johnny Uy, Jinglan Zhou, Alexander Russell Abela, Brett Bradley Busch, Prasuna Paraselli, David Andrew Siesel
  • Publication number: 20190274070
    Abstract: Disclosed herein are systems and methods for the creation, maintenance and management of virtual overlay networks across multiple communication networks managed by service providers. The simple creation and management of network overlays is accomplished via a network orchestrator manager, allowing for automation of configuration of connected network devices throughout an entire organization's network, regardless of the physical location of each device.
    Type: Application
    Filed: May 16, 2019
    Publication date: September 5, 2019
    Inventors: David Anthony Hughes, Santosh Bheemarajaiah, Damon John Ennis, David Holt Merwin, Rolf Muralt, Pawan Kumar Singh, Theodore Ernest Tedijanto, Lokesh Lingarajan, Edward P. Travalia, Krishna Kumar Sadasivam, Shyh Pei Yen, Abhelaksh Thakur, Catrina A. Torda
  • Patent number: 10313930
    Abstract: Disclosed herein are systems and methods for the creation, maintenance and management of virtual overlay networks across multiple communication networks managed by service providers. The simple creation and management of network overlays is accomplished via a network orchestrator manager, allowing for automation of configuration of connected network devices throughout an entire organization's network, regardless of the physical location of each device.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: June 4, 2019
    Assignee: Silver Peak Systems, Inc.
    Inventors: David Anthony Hughes, Santosh Bheemarajaiah, Damon John Ennis, David Holt Merwin, Rolf Muralt, Pawan Kumar Singh, Theodore E. Tedijanto, Lokesh Lingarajan, Edward P. Travalia, Krishna Kumar Sadasivam, Shyh Pei Yen, Abhelaksh Thakur, Catrina A. Torda
  • Publication number: 20190149447
    Abstract: Disclosed is a system and method for the dynamic monitoring of network health characteristics via a visualization platform. The platform receives collected information regarding network health characteristics and applies a rule set defining at least one threshold to classify each of the network health characteristics for each network component over a time period. The classifications can be represented visually on a graphical user interface to a network administrator, allowing the administrator to quickly discern which aspects of the network are operating properly and which aspects are not.
    Type: Application
    Filed: December 18, 2018
    Publication date: May 16, 2019
    Inventors: David Anthony Hughes, Santosh Bheemarajaiah, Damon John Ennis, David Holt Merwin, Rolf Muralt, Onur Ozduygu, Kevin James Roselle, Pawan Kumar Singh
  • Patent number: 9686990
    Abstract: Insecticidal, acaricidal, nematicidal or molluscicidal compounds of formula (I) wherein Y is a single bond, C?O, C?S or S(O)q where q is 0, 1 or 2; and R1, R2, R3, R4, R8, R9 are R10 are as defined in the claims or salts or N-oxides thereof, processes for preparing them and compositions containing them.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: June 27, 2017
    Assignee: Syngenta Participations AG
    Inventors: David John Hughes, Paul Anthony Worthington, Charles Adam Russell, Eric Daniel Clarke, James Edward Peace, Mark Richard Ashton, Thomas Stephen Coulter, Richard Spurring Roberts, Louis-Pierre Molleyres, Fredrik Cederbaum, Jerome Cassayre, Peter Maienfisch
  • Publication number: 20170161802
    Abstract: A WIP management system is disclosed that comprises a data storage device arranged to store work in progress (WIP) data indicative of work in progress financial amounts associated with at least one person, and a filter arranged to facilitate filtering of the WIP data according to received criteria so as to produce filtered WIP data. The system is arranged to facilitate display of filtered WIP information indicative of the filtered WIP data, to facilitate selection by a user of WIP from the filtered WIP information and to instigate invoice processing based on the selected WIP. A corresponding method of managing WIP is also disclosed.
    Type: Application
    Filed: March 18, 2014
    Publication date: June 8, 2017
    Inventors: David John Hughes, David Carson, Andrew Leigh Prittchett
  • Publication number: 20160140630
    Abstract: A WIP management system is disclosed that comprises a data storage device arranged to store work in progress (WIP) data indicative of work in progress financial amounts associated with at least one person, and a filter arranged to facilitate filtering of the WIP data according to received criteria so as to produce filtered WIP data. The system is arranged to facilitate display of filtered WIP information indicative of the filtered WIP data, to facilitate selection by a user of WIP from the filtered WIP information and to instigate invoice processing based on the selected WIP. A corresponding method of managing WIP is also disclosed.
    Type: Application
    Filed: March 18, 2014
    Publication date: May 19, 2016
    Inventors: David John Hughes, David Carson, Andrew Leigh Prittchett
  • Publication number: 20160007608
    Abstract: Insecticidal, acaricidal, nematicidal or molluscicidal compounds of formula (I) wherein Y is a single bond, C?O, C?S or S(O)q where q is 0, 1 or 2; and R1, R2, R3, R4, R8, R9 are R10 are as defined in the claims or salts or N-oxides thereof, processes for preparing them and compositions containing them.
    Type: Application
    Filed: September 21, 2015
    Publication date: January 14, 2016
    Applicants: SYNGENTA LIMITED, SYNGENTA PARTICIPATIONS AG
    Inventors: David John Hughes, Paul Anthony Worthington, Charles Adam Russell, Eric Daniel Clarke, James Edward Peace, Mark Richard Ashton, Thomas Stephen Coulter, Richard Spurring Roberts, Louis-Pierre Molleyres, Fredrik Cederbaum, Jerome Cassayre, Peter Maienfisch
  • Patent number: 9174987
    Abstract: Insecticidal, acaricidal, nematicidal or molluscicidal compounds of formula (I) wherein Y is a single bond, C?O, C?S or S(O)q where q is 0, 1 or 2; and R1, R2, R3, R4, R8, R9 are R10 are as defined in the claims or salts or N-oxides thereof, processes for preparing them and compositions containing them.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: November 3, 2015
    Assignees: Syngenta Limited, Syngenta Participations AG
    Inventors: David John Hughes, Paul Anthony Worthington, Charles Adam Russell, Eric Daniel Clarke, James Edward Peace, Mark Richard Ashton, Thomas Stephen Coulter, Richard Spurring Roberts, Louis-Pierre Molleyres, Fredrik Cederbaum, Jerome Cassayre, Peter Maienfisch
  • Patent number: 8658801
    Abstract: Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: February 25, 2014
    Assignees: Syngenta Crop Protection, LLC, Syngenta Limited
    Inventors: Olivier Loiseleur, Patricia Durieux, Stephan Trah, Andrew Edmunds, André Jeanguenat, André Stoller, David John Hughes
  • Patent number: 8106075
    Abstract: Compounds of formula I wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    Type: Grant
    Filed: October 10, 2005
    Date of Patent: January 31, 2012
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Anthony Cornelius O'Sullivan, David John Hughes, André Jeanguenat, Michel Muehlebach, Olivier Loiseleur
  • Publication number: 20120010220
    Abstract: Insecticidal, acaricidal, nematicidal or molluscicidal compounds of formula (I) wherein Y is a single bond, C?O, C?S or S(O)q where q is 0, 1 or 2; and R1, R2, R3, R4, R8, R9 are R10 are as defined in the claims or salts or N-oxides thereof, processes for preparing them and compositions containing them.
    Type: Application
    Filed: September 16, 2011
    Publication date: January 12, 2012
    Applicant: SYNGENTA CROP PROTECTION LLC
    Inventors: David John Hughes, Paul Anthony Worthington, Charles Adam Russell, Eric Daniel Clarke, James Edward Peace, Mark Richard Ashton, Thomas Stephen Coulter, Richard Spurring Roberts, Louis-Pierre Molleyres, Fredrik Cederbaum, Jerome Cassayre, Peter Maienfisch
  • Patent number: 7812170
    Abstract: Compounds of the formula (I) in which Z, is an oxygen atom; or a sulfur atom; Z2 is an oxygen atom; or a sulfur atom; R, is an aryl or heteroaryl group, which is unsubstituted or substituted; R2 is hydrogen; or an organic substituent; R3 is hydrogen; or an organic substituent; R4 is hydrogen; or an organic substituent; or R3 and R4, taken together, form, together with the nitrogen atom, to which they are attached, a ring, which is unsubstituted or substituted; R5 is hydrogen; or an unsubstituted or substituted alkyl group; or forms, taken together with R8 or with a monovalent substituent attached to that atom of R6, via which atom R6 is directly connected with the carbon atom, shown in the formula I, which carries R5, one additional bond; R6 and R7, taken together, form, together with the two carbon atoms, shown in the formula I, to which atoms they are attached, a bicyclic ring system, which ring system is carbocyclic or heterocyclic, which ring system is substituted, in the manner shown in the formula I, by
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: October 12, 2010
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: David John Hughes, James Edward Peace, Suzanna Riley, Sally Russell, Joseph John Swanborough, Roger Graham Hall, André Jeanguenat, Olivier Loiseleur, Peter Renold, Stephan Trah, Jean Wenger
  • Publication number: 20090298816
    Abstract: Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    Type: Application
    Filed: February 14, 2007
    Publication date: December 3, 2009
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Olivier Loiseleur, Patricia Durieux, Stephan Trah, Andrew Edmunds, Andre Jeanguenat, Andre Stoller, David John Hughes
  • Publication number: 20080275065
    Abstract: Compounds of formula I wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    Type: Application
    Filed: October 10, 2005
    Publication date: November 6, 2008
    Applicants: SYNGENTA CROP PROTECTION, INC., SYNGENTA LIMITED
    Inventors: Anthony Cornelius O'Sullivan, David John Hughes, Andre Jeanguenat, Michel Muehlebach, Olivier Loiseleur
  • Patent number: 7112553
    Abstract: A compound of formula (I) wherein G is either (i) or (ii), where M1 or M2 is bonded to A; n is 0 or 1; when G is (i), D is S, NR7, CR8?CR9, CR8?N, CR8?N(O), N?CR9 or N(O)?CR9; when G is (ii), D is S or NR7; E is N, N-oxide or CR10; M1 is OC(?Y), N(R11)C(?Y), N?C(OR12), N?C(SR13) or N?C(NR14R15) where O or N is the atom of attachment to the ring containing D and E; M2 is N—C(?Y) where N is the atom of attachment to the ring containing D and E; Y is O, S or NR16; J is N or CR17; and A, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14 and R15 are each certain organic or inorganic groups. These compounds are useful in fungicidal, insecticidal, acaricidal, molluscicidal and hematicidal compositions.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: September 26, 2006
    Assignee: Syngenta Limited
    Inventors: Sarah Armstrong, Nigel John Barnes, Susan Patricia Barnett, Eric Daniel Clarke, Patrick Jelf Crowley, Torquil Eoghan Macleod Fraser, David John Hughes, Christopher John Mathews, Joan Pilkington, legal representative, Roger Salmon, Stephen Christopher Smith, Russell Viner, William Guy Whittingham, John Williams, Alan John Whittle, Brian Leslie Pilkington, deceased
  • Publication number: 20060106045
    Abstract: Insecticidal, acaricidal, nematicidal or molluscicidal compounds of formula (I) wherein Y is a single bond, C?O, C?S or C?(O)q where q is 0, 1 or 2; and R1, R2, R3, R4, R8, R9 and R10 are as defined in the claims or salts or N-oxides thereof, processes for preparing them and compositions containing them.
    Type: Application
    Filed: June 4, 2003
    Publication date: May 18, 2006
    Inventors: David John Hughes, Paul Worthington, Charles Russell, Eric Clarke, James Peace, Mark Ashton, Thomas Coulter, Richard Roberts, Louis-Pierre Molleyres, Fredrik Cederbaum, Jerome Cassayre, Peter Maienfisch
  • Patent number: 6703347
    Abstract: A compound of formula (I), where A is optionally substituted alkylene, alkenylene, alkynylene, cycloalkylene, alkylenoxy, oxy(C1-6)alkylene, alkylenthio, thio(C1-6)alkylene, C1-6alkylenamino, amino(C1-6)alkylene, [C1-6alkyleneoxy(C1-6)alkylene], [C1-6alkylenethio(C1-6)alkylene], [1-6alkylenesulfinyl(C1-6)alkylene], [C1-6alkylenesulfonyl(C1-6)alkylene] or [C1-6alkyleneamino(C1-6)alkylene]; provided that A is not CH2 or CH2O; B is N,N-oxide or CR8; Y is O, S or NR9; Z is O, S or NR10; and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 are specified radicals; compositions containing them; process for making them; and their use as insecticides or fungicides.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: March 9, 2004
    Assignee: Syngenta Limited
    Inventors: Sarah Armstrong, Nigel John Barnes, Susan Patricia Barnett, Eric Daniel Clarke, Patrick Jelf Crowley, Torquil Eoghan Macleod Fraser, David John Hughes, Christopher John Mathews, Roger Salmon, Stephen Christopher Smith, Russell Viner, William Guy Whittingham, John Williams, Alan John Whittle, William Roderick Mound, Christopher John Urch, Brian Leslie Pilkington
  • Publication number: 20030207926
    Abstract: A compound of formula (I), where A is optionally substituted alkylene, alkenylene, alkynylene, cycloalkylene, alkylenoxy, oxy(C1-6)alkylene, alkylenethio, thio(C1-6)alkylene, C1-6alkylenamino, amino(C1-6)alkylene, [C1-6alkyleneoxy(C1-6)alkylene], [C1-6alkylenethio(c1-6)alkylene], [1-6alkylenesulfinyl(c1-6)alkylene], [c1-6alkylenesulfonyl(C1-6)alkylenc] or [C1-6alkyleneamino(C1-6)alkylene]; provided that A is not CH2 or CH2O; B is N, N-oxide or CR8; Y is O, S or NR9; Z is O, S or NR10; and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 are specified radicals; compositions containing them; processes for making them; and their use as insecticides or fungicides.
    Type: Application
    Filed: November 7, 2002
    Publication date: November 6, 2003
    Inventors: Sarag Armstrong, Nigel John Barnes, Susan Patricia Barnett, Eric Daniel Clarke, Patrick Jelf Crowley, Torquil Eoghan Macleod Fraser, David John Hughes, Christopher John Mathews, Roger Salmon, Stephen Christopher Smith, Russell Viner, William Guy Whittingham, John Williams, Alan John Whittle, William Roderick Mound, Christopher John Urch, Brian Leslie Pilkington, Joan Pilkington
  • Patent number: 6544989
    Abstract: The invention provides compounds of formula (I): where the substituents are as defined in the specification. The invention also provides processes for preparing the compounds, compositions comprising the compounds, methods of using the compounds and compositions to combat fungal diseases, and methods of using the compounds and compositions to combat or control insect, acarine, mollusc and nematode pests.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: April 8, 2003
    Assignee: Syngenta Limited
    Inventors: Christopher John Mathews, Russell Viner, Susan Patricia Barnett, Christopher John Urch, Stephen Christopher Smith, Patrick Jelf Crowley, William Guy Whittingham, Stephen Paul Heaney, John Williams, Torquil Eoghan Macleod Fraser, Eric Daniel Clarke, David John Hughes, Sarah Armstrong, Nigel John Barnes, Alan John Whittle, Brian Leslie Pilkington