Patents by Inventor David M. Kaye

David M. Kaye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11633538
    Abstract: A system for modulating delivery of a fluid medium includes an injector for injecting the fluid medium during an injection cycle, a delivery catheter including a conduit for delivering the fluid medium, a manifold disposed in a fluid medium flow path between the injector and the delivery catheter, and a pulsatile generator. The pulsatile generator is configured to apply a pulsatile force to the fluid medium defined by a plurality of duty cycles during the injection cycle, each of the duty cycles including a first pressure level and a second pressure level that is lower than the first pressure level.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: April 25, 2023
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Patent number: 11623036
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Grant
    Filed: November 11, 2019
    Date of Patent: April 11, 2023
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Publication number: 20220211942
    Abstract: A system for delivering an amount of fluid medium includes an injector, a delivery catheter and a pulsatile generator. The injector is configured for injecting the fluid medium during an injection cycle. The delivery catheter includes a conduit for delivering the fluid medium. The pulsatile generator is configured to apply a pulsatile force on the fluid medium delivered through the delivery catheter at a pulsation frequency. The pulsatile force is defined by a plurality of duty cycles during the injection cycle, each of the plurality of duty cycles including a first flow level and a second flow level that is lower than the first flow level. The pulsation frequency is 3 or more duty cycles per second.
    Type: Application
    Filed: February 11, 2022
    Publication date: July 7, 2022
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Patent number: 11235099
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: February 1, 2022
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Patent number: 10835670
    Abstract: Systems and methods for modulating delivery of a fluid medium to a selected site within a patient's body are described. A system includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a diversion reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe. The flow diverter assembly simultaneously increases fluid medium flow resistance with increasing pressure level of the fluid medium passing into the flow diverter assembly.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: November 17, 2020
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Publication number: 20200345933
    Abstract: A system for modulating delivery of a fluid medium includes an injector for injecting the fluid medium during an injection cycle, a delivery catheter including a conduit for delivering the fluid medium, a manifold disposed in a fluid medium flow path between the injector and the delivery catheter, and a pulsatile generator. The pulsatile generator is configured to apply a pulsatile force to the fluid medium defined by a plurality of duty cycles during the injection cycle, each of the duty cycles including a first pressure level and a second pressure level that is lower than the first pressure level.
    Type: Application
    Filed: May 11, 2020
    Publication date: November 5, 2020
    Inventors: Matthew M. Burns, Tuan M, Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Publication number: 20200069867
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Application
    Filed: November 11, 2019
    Publication date: March 5, 2020
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Publication number: 20190307951
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Application
    Filed: May 21, 2019
    Publication date: October 10, 2019
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Patent number: 10335539
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: July 2, 2019
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Patent number: 10279104
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: May 7, 2019
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Publication number: 20180185576
    Abstract: A system for modulating delivery of a fluid medium to a selected site within a patient's body includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The syringe includes a chamber for receiving the fluid medium therein. The flow diverter assembly is configured to simultaneously divert at least some of the fluid medium within the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe, and wherein the flow diverter assembly creates increasing medium fluid flow resistance with increasing pressure level of the fluid medium within the flow diverter assembly. A method for modulating fluid delivery to a selected site within a patient's body is also disclosed.
    Type: Application
    Filed: February 28, 2018
    Publication date: July 5, 2018
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Patent number: 10010673
    Abstract: A system for modulating delivery of a fluid medium to a selected site within a patient's body includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a medium reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The syringe includes a chamber for receiving the fluid medium therein. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe, and simultaneously increase medium fluid flow resistance with increasing pressure level of the fluid medium within the flow diverter assembly.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: July 3, 2018
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Publication number: 20160310660
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Application
    Filed: March 25, 2016
    Publication date: October 27, 2016
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Patent number: 9320846
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 26, 2016
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Publication number: 20160106915
    Abstract: A system for modulating delivery of a fluid medium to a selected site within a patient's body includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The syringe includes a chamber for receiving the fluid medium therein. The flow diverter assembly is configured to simultaneously divert at least some of the fluid medium within the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe, and wherein the flow diverter assembly creates increasing medium fluid flow resistance with increasing pressure level of the fluid medium within the flow diverter assembly. A method for modulating fluid delivery to a selected site within a patient's body is also disclosed.
    Type: Application
    Filed: September 11, 2015
    Publication date: April 21, 2016
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Publication number: 20150265761
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Application
    Filed: March 17, 2015
    Publication date: September 24, 2015
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Publication number: 20140066891
    Abstract: Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 6, 2014
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Daniel R. Mans, Todd J. Mortier
  • Patent number: 7956219
    Abstract: In the present specification we describe a new class of compounds, designed to modulate the ability of blood vessels to synthesize NO from L-arginine. In particular we have identified novel compounds which enhance the entry of L-arginine into cells. These compounds improve endothelial function, and thereby have the potential to retard the progression of vascular disease in conditions such as hypertension, heart failure and diabetes. This new class of drugs may also have other potentially, relevant pharmacological actions, including anti-hypertensive and anti-anginal actions.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: June 7, 2011
    Assignee: Baker IDI Heart and Diabetes
    Inventors: Nicholas J. Ede, David M. Kaye, Robert W. Trainor, Andrew N. Hunter
  • Patent number: 7591826
    Abstract: A device, system and method provides mitral valve therapy. The device is implantable in the coronary sinus of the heart to partially encircle the mitral valve annulus. The device is elongated, is resilient, and has a preformed arched configuration. When the device is implanted in the coronary sinus, the device exerts a substantially radially inward force to the mitral valve to restore mitral valve annulus geometry.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: September 22, 2009
    Assignee: Cardiac Dimensions, Inc.
    Inventors: Clifton A. Alferness, David M. Kaye
  • Publication number: 20020087173
    Abstract: A device, system and method for treating a mitral valve is disclosed. The device is implantable in the coronary sinus of the heart to partially encircle the mitral valve annulus. The device is elongated, is resilient, and has a preformed arched configuration. When the device is implanted in the coronary sinus, the device exerts a substantially radially inward force to the mitral valve to restore mitral valve annulus geometry.
    Type: Application
    Filed: December 28, 2000
    Publication date: July 4, 2002
    Inventors: Clifton A. Alferness, David M. Kaye