Patents by Inventor David P. Dumas

David P. Dumas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6911339
    Abstract: The invention provides polyol (allyl carbonate) polymer solid supports. The supports can be modified for attachment of a chemical moiety or ligand. A solid support comprising one or more ligands immobilized to a polyol (allyl carbonate) polymer solid support. The solid support can be in the form of a bead, fiber, flat surface, microfluidic device, molded device, machined device, container, multi-well container such as a multi-well plate, and mass spectrometry sample holder. The solid supports can be used for a variety of applications, including chemical storage, chemical synthesis, combinatorial library synthesis, analytical devices, diagnostic devices, and tissue culture applications. The invention also provides methods of using the polyol (allyl carbonate) polymer solid supports.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: June 28, 2005
    Inventor: David P. Dumas
  • Publication number: 20040118688
    Abstract: The invention provides polyol (allyl carbonate) polymer for electrokinetic devices. The devices can be modified for attachment of a chemical moiety or ligand. The electrokinetic devices can be used for a variety of applications, including chemical analysis, biochemical analysis, cell sorting, purification, analytical devices, diagnostic devices, and tissue culture applications. The invention also provides methods of using the polyol (allyl carbonate) polymer electrokinetic devices. The invention also provides for a sensor that allows for the detection of various chemicals, biochemicals, ions, metals, solvents, and bio-polymers.
    Type: Application
    Filed: July 29, 2003
    Publication date: June 24, 2004
    Inventor: David P. Dumas
  • Publication number: 20030022394
    Abstract: The invention provides a method of generating an array of molecules. The method includes the steps of attaching one or more chemical moieties to a plurality of waveguides; distributing the plurality of waveguides in a predetermined arrangement in a grid, the grid thereby spacing the waveguides at a predetermined distance; embedding the plurality of waveguides in an inert support; and slicing the embedded plurality of waveguides transversely, thereby generating an array of molecules. A non-end portion of the embedded waveguides can be removed from at least one face of the slice. The waveguides can also be coated with cladding to effect spacing at a predetermined distance. The invention also provides compositions comprising a plurality of waveguides embedded in an inert support, the waveguides having attached thereto one or more chemical moieties, having a non-end portion exposed, and being spaced at a distance to minimize crosstalk between waveguides.
    Type: Application
    Filed: July 26, 2002
    Publication date: January 30, 2003
    Inventor: David P. Dumas
  • Publication number: 20030013188
    Abstract: The invention provides polyol (allyl carbonate) polymer solid supports. The supports can be modified for attachment of a chemical moiety or ligand. A solid support comprising one or more ligands immobilized to a polyol (allyl carbonate) polymer solid support. The solid support can be in the form of a bead, fiber, flat surface, microfluidic device, molded device, machined device, container, multi-well container such as a multi-well plate, and mass spectrometry sample holder. The solid supports can be used for a variety of applications, including chemical storage, chemical synthesis, combinatorial library synthesis, analytical devices, diagnostic devices, and tissue culture applications. The invention also provides methods of using the polyol (allyl carbonate) polymer solid supports.
    Type: Application
    Filed: April 8, 2002
    Publication date: January 16, 2003
    Inventor: David P. Dumas
  • Publication number: 20020139936
    Abstract: The invention provides an apparatus for fluorescence detection, comprising a light source for illuminating a portion of a solid support; a means for splitting light emanating from the light source into two or more split beams of light; a means for polarizing the beams of light; a means for collimating the polarized light; a ¼-wave plate disposed between the collimating means and the solid support for converting the collimated light into polarized light; a means for focusing the polarized light onto the solid support; a means for detecting a fluorescence emission; a means for filtering the fluorescence emission; and a photodetector array.
    Type: Application
    Filed: October 25, 2001
    Publication date: October 3, 2002
    Inventor: David P. Dumas
  • Publication number: 20020110843
    Abstract: The invention provides a composition comprising a diverse population of reagent ligands attached to a solid support and a diverse population of reagent antibodies specifically bound to the reagent ligands. The ligands can be peptides, oligosaccharides, oligonucleotides, or organic molecules. The invention additionally provides methods of determining an epitope in a sample contacting a composition comprising a diverse population of ligands attached to a solid support and a diverse population of antibodies specifically bound to each of the ligands with a sample; and detecting the antibodies bound to the diverse population of ligands. The invention further provides methods of diagnosing a disease, identifying a potential therapeutic agent, and mapping accessible epitopes of a polypeptide using invention compositions.
    Type: Application
    Filed: May 10, 2001
    Publication date: August 15, 2002
    Inventor: David P. Dumas
  • Publication number: 20020109979
    Abstract: The invention provides an apparatus for chemical synthesis comprising a light source, for example, a laser light source; a means for dispensing a chemical reagent onto the solid support; a means for splitting light emanating from the light source into two or more split beams of light; a means for polarizing the beams of light; a means for collimating the polarized light; a ¼-wave plate disposed between the collimating means and the solid support; a means for focusing the polarized light onto the solid support; and a photodetector array.
    Type: Application
    Filed: October 25, 2001
    Publication date: August 15, 2002
    Inventor: David P. Dumas