Patents by Inventor David S. Newburg

David S. Newburg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITING INFLAMMATION WITH MILK OLIGOSACCHARIDES
    Publication number: 20230101412
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Application
    Filed: May 4, 2022
    Publication date: March 30, 2023
    Applicants: Children's Hospital Medical Center, The General Hospital Corporation d/b/a Massachusetts General Hospital, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • Fucosylated oligosaccharides for prevention of coronavirus infection
    Patent number: 11331329
    Abstract: The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection and/or to promote recovery from a respiratory pathogen infection in the respiratory system and/or the GI tract of a subject.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: May 17, 2022
    Assignee: Glycosyn LLC
    Inventors: Ardythe L. Morrow, David S. Newburg, John M. McCoy
  • Inhibiting inflammation with milk oligosaccharides
    Patent number: 11324765
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: May 10, 2022
    Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • 2'-fucosyllactose for the prevention and treatment of coronavirus-induced inflammation
    Patent number: 11324766
    Abstract: The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection-induced host inflammation and/or to promote recovery from a respiratory pathogen infection-induced host inflammation in a subject.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: May 10, 2022
    Assignee: Glycosyn LLC
    Inventors: Ardythe L. Morrow, David S. Newburg, John M. McCoy
  • TREATMENT OF INFLAMMATORY BOWEL DISEASES WITH 2'-FUCOSYLLACTOSE COMPOUNDS
    Publication number: 20220133758
    Abstract: Provided herein are 2?-fucosyllactose compounds and methods of using such for treating inflammatory bowel diseases (IBD) (e.g., Crohn's disease (CD) or ulcerative colitis (UC)) or alleviating or reducing the risk of relapse in IBD.
    Type: Application
    Filed: November 11, 2021
    Publication date: May 5, 2022
    Applicant: CHILDREN'S HOSPITAL MEDICAL CENTER
    Inventors: Ardythe L. MORROW, Lee A. DENSON, David S. NEWBURG
  • 2'-FUCOSYLLACTOSE FOR THE PREVENTION AND TREATMENT OF CORONAVIRUS-INDUCED INFLAMMATION
    Publication number: 20210353653
    Abstract: The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection-induced host inflammation and/or to promote recovery from a respiratory pathogen infection-induced host inflammation in a subject.
    Type: Application
    Filed: May 13, 2021
    Publication date: November 18, 2021
    Inventors: Ardythe L. Morrow, David S. Newburg, John M. McCoy
  • FUCOSYLATED OLIGOSACCHARIDES FOR PREVENTION OF CORONAVIRUS INFECTION
    Publication number: 20210353654
    Abstract: The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection and/or to promote recovery from a respiratory pathogen infection in the respiratory system and/or the GI tract of a subject.
    Type: Application
    Filed: May 13, 2021
    Publication date: November 18, 2021
    Inventors: Ardythe L. Morrow, David S. Newburg, John M. McCoy
  • INHIBITING INFLAMMATION WITH MILK OLIGOSACCHARIDES
    Publication number: 20210283155
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Application
    Filed: May 28, 2021
    Publication date: September 16, 2021
    Applicants: Children's Hospital Medical Center, The General Hospital Corporation d/b/a Massachusetts General Hospital, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • Inhibiting inflammation with milk oligosaccharides
    Patent number: 11058697
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: July 13, 2021
    Assignees: CHILDREN'S HOSPITAL MEDICAL CENTER, INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION, THE GENERAL HOSPITAL CORPORATION
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • TREATMENT OF INFLAMMATORY BOWEL DISEASES WITH 2'-FUCOSYLLACTOSE COMPOUNDS
    Publication number: 20200129534
    Abstract: Provided herein are 2?-fucosyllactose compounds and methods of using such for treating inflammatory bowel diseases (IBD) (e.g.
    Type: Application
    Filed: April 7, 2018
    Publication date: April 30, 2020
    Applicant: CHILDREN'S HOSPITAL MEDICAL CENTER
    Inventors: Ardythe L. MORROW, Lee A. DENSON, David S. NEWBURG
  • USE OF PURIFIED 2'-FUCOSYLLACTOSE, 3-FUCOSYLLACTOSE AND LACTODIFUCOTETRAOSE AS PREBIOTICS
    Publication number: 20190255083
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 22, 2019
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Use of purified 2?-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
    Patent number: 10286001
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: May 14, 2019
    Assignees: Glycosyn LLC, Trustees of Boston College
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Inhibiting inflammation with milk oligosaccharides
    Publication number: 20190099435
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Application
    Filed: August 16, 2018
    Publication date: April 4, 2019
    Applicants: Children's Hospital Medical Center, The General Hospital Corporation d/b/a Massachusetts General Hospital, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • Inhibiting inflammation with milk oligosaccharides
    Patent number: 10098903
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: October 16, 2018
    Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • PROTEASE COMPOSITIONS FOR USE IN MODIFYING SEMEN
    Publication number: 20170354594
    Abstract: Provided herein are edible compositions for reducing semen viscosity and/or enhancing semen flavor, and methods of using and preparing such compositions.
    Type: Application
    Filed: November 19, 2015
    Publication date: December 14, 2017
    Inventors: Marc L. Berger, David S. Newburg
  • USE OF PURIFIED 2?-FUCOSYLLACTOSE, 3-FUCOSYLLACTOSE AND LACTODIFUCOTETRAOSE AS PREBIOTICS
    Publication number: 20170136049
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Use of purified 2?-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
    Patent number: 9567361
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: February 14, 2017
    Assignees: Glycosyn LLC, Trustees of Boston College
    Inventors: David S Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • INHIBITING INFLAMMATION WITH MILK OLIGOSACCHARIDES
    Publication number: 20150306120
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Application
    Filed: April 30, 2015
    Publication date: October 29, 2015
    Applicants: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • PREBIOTIC EFFECT OF SIALYLLACTOSE
    Publication number: 20150265661
    Abstract: Provided herein are prebiotic compositions comprising a combination of oligosaccharides such as sialyated oligosaccharides and fusocylated oligosaccharides, and uses thereof in stimulating the proliferation of beneficial intestinal micro biota, for example, of bifidobacteria, and/or in decreasing the abundance of enteric pathogens. The prebiotic compositions can further contain a probiotic, which can be a population of bifidobacteria, lactobacilli, Bacteriodes fragilis, Bacteriodes thetaiotaomicron, Enterococcus faecalis (pro biotic strains thereof), Staphylococcus epidermides, Enterobacter aerogenes, Enterobacter cloacae, or related bacteria having similar functions.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 24, 2015
    Applicant: Trustees of Boston College
    Inventors: David S. Newburg, Zhuoteng Yu
  • Use of secretor, Lewis and sialyl antigen levels in clinical samples as predictors of risk for disease
    Patent number: 9132142
    Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: September 15, 2015
    Assignees: The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion, Children's Hospital Medical Center
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios