Patents by Inventor David Schwartzman

David Schwartzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210275642
    Abstract: The present invention includes methods, systems, uses, and means for the delivery of one or more anti-fibrotic agents into the pericardial space for the treatment and prevention of heart failure (HF).
    Type: Application
    Filed: December 17, 2020
    Publication date: September 9, 2021
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: David Schwartzman, Sanjeev G. Shroff, Guy Salama, Charles McTiernan
  • Publication number: 20200378920
    Abstract: A biomarker detection device comprising: a microfluidic biosensor further comprising a biomarker functionalized polymer single nanowire connecting a pair of gold electrodes on a silicon wafer; the biomarker functionalized polymer single nanowire s coupled to a gate electrode by a liquid electrolyte gate; and a tunable gate voltage connected to the gate electrode.
    Type: Application
    Filed: July 15, 2020
    Publication date: December 3, 2020
    Inventors: Minhee Yun, David Schwartzman, Jiyong Huang
  • Patent number: 10684250
    Abstract: A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: June 16, 2020
    Assignee: University of Pittsburgh—Of The Commonwealth System of Higher Education
    Inventors: Minhee Yun, David Schwartzman, Jiyong Huang
  • Publication number: 20190257785
    Abstract: A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire.
    Type: Application
    Filed: April 25, 2016
    Publication date: August 22, 2019
    Inventors: Minhee Yunn, David Schwartzman, Jiyong Huang
  • Publication number: 20180192991
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Application
    Filed: January 4, 2018
    Publication date: July 12, 2018
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong
  • Patent number: 9861338
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: January 9, 2018
    Assignees: Carnegie Mellon University, University Of Pittsburgh—of The Commonwealth System
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong
  • Publication number: 20170182128
    Abstract: The present invention includes methods, systems, uses, and means for the delivery of one or more anti-fibrotic agents into the pericardial space for the treatment and prevention of heart failure (HF).
    Type: Application
    Filed: March 10, 2017
    Publication date: June 29, 2017
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: David Schwartzman, Sanjeev G. Shroff, Guy Salama, Charles McTiernan
  • Patent number: 9649393
    Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and methods for image-guided treatment and/or diagnosis of a subject with a condition associated with an inflammatory response in an internal organ. The disclosure additionally provides methods for image-guided treatment of myocardial infarction (MI) in a subject.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: May 16, 2017
    Assignees: University of Pittsburgh-of the Commonwealth System of Higher Education, Carnegie Mellon University
    Inventors: Eric T. Ahrens, David Schwartzman
  • Patent number: 9622821
    Abstract: A method for fusing information related to structural features and characteristics of a biological sample. The resulting fused image may be imported into a surgical navigation technology intra-operatively to aid in surgical interventions by co-registering the fused image with the patient's anatomical features.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: April 18, 2017
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Carnegie Mellon University
    Inventors: Prahlad Menon Gopalakrishna, Daniel Ryder Ludwig, David Schwartzman
  • Patent number: 9566043
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: February 14, 2017
    Assignees: Carnegie Mellon University, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong
  • Publication number: 20160313277
    Abstract: A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire.
    Type: Application
    Filed: April 25, 2016
    Publication date: October 27, 2016
    Inventors: Minhee Yunn, David Schwartzman, Jiyong Huang
  • Publication number: 20160256131
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Application
    Filed: April 20, 2015
    Publication date: September 8, 2016
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong
  • Patent number: 9347939
    Abstract: A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: May 24, 2016
    Assignee: University of Pittsburgh—Of The Commonwealth System of Higher Education
    Inventors: Minhee Yun, David Schwartzman, Jiyong Huang
  • Publication number: 20150257845
    Abstract: A method for fusing information related to structural features and characteristics of a biological sample. The resulting fused image may be imported into a surgical navigation technology intra-operatively to aid in surgical interventions by co-registering the fused image with the patient's anatomical features.
    Type: Application
    Filed: October 11, 2013
    Publication date: September 17, 2015
    Applicant: Camegie Mellon University
    Inventors: Prahlad Menon Gopalakrishna, Daniel Ryder Ludwig, David Schwartzman
  • Patent number: 9017260
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: April 28, 2015
    Assignees: Carnegie Mellon University, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong
  • Publication number: 20140154785
    Abstract: A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire.
    Type: Application
    Filed: May 23, 2013
    Publication date: June 5, 2014
    Inventors: Minhee Yun, David Schwartzman, Jiyong Huang
  • Publication number: 20140093452
    Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and methods for image-guided treatment and/or diagnosis of a subject with a condition associated with an inflammatory response in an internal organ. The disclosure additionally provides methods for image-guided treatment of myocardial infarction (MI) in a subject.
    Type: Application
    Filed: September 17, 2013
    Publication date: April 3, 2014
    Inventors: Eric T. Ahrens, David Schwartzman
  • Publication number: 20130345555
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Application
    Filed: June 12, 2013
    Publication date: December 26, 2013
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong
  • Publication number: 20130197468
    Abstract: Methods and apparatuses for delivery of biologically active material and/or sensors to a target organ or system. The apparatuses allow for specific, controlled delivery of the biologically active material and targeted placement of sensors. The apparatuses may be fabricated from cellular and/or acellular biological active components to promote integration of sensors into tissue and achieve appropriate release of biologically active molecules. The apparatuses may be fabricated from plasma-containing materials or other biopolymers such that the apparatus will resorbed into the tissue following insertion. The biologically active cellular or acellular component may be incorporated into that material may then serve as the source of the therapeutic biologically active component. The apparatus may take the form of a screw, though numerous shapes arc contemplated.
    Type: Application
    Filed: January 28, 2013
    Publication date: August 1, 2013
    Applicants: CARNEGIE MELLON UNIVERSITY, University of Pittsburgh-of the Commonwealth System of Higher Education
    Inventors: David SCHWARTZMAN, Lee E. Weiss, Phil Gordon Campbell, Gary K. Fedder
  • Patent number: 8480588
    Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: July 9, 2013
    Assignees: Carnegie Mellon University, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Takeo Kanade, David Schwartzman, Hua Zhong