Patents by Inventor David T. Bailey

David T. Bailey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6960360
    Abstract: This invention provides a process for the preparation of compositions enriched in total phenols from a crude plant extract. The process includes a novel column purification step using a brominated polystyrene resin. This invention also includes compositions enriched in total phenols. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols and having HPLC chromatograms substantially as set forth in FIGS. 10-13. This invention encompasses methods of using the total phenol-enriched compositions for treating warm-blooded animals, including humans, infected with paramyxovaridae such as respiratory syncytial virus, orthomyoxovaridae such as influenza A, B, and C, parainfluenza, Herpes viruses such as HSV-1 and HSV-2, and Flaviviruses such as West Nile Virus, and for treating inflammation such as caused by arthritis, stress and digestive disease.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: November 1, 2005
    Assignee: Phenolics, LLC
    Inventors: Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, David T. Bailey, Rebecca L. Nichols, F. Joseph Daugherty, Delano R. Freeberg
  • Patent number: 6780442
    Abstract: This invention includes both a one-column process and a two-column process for the preparation of compositions enriched for anthocyanins from a crude plant extract. Both processes include a novel column purification step using a brominated polystyrene resin. This invention also includes extracts enriched for anthocyanins.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: August 24, 2004
    Assignee: Hauser, Inc.
    Inventors: David T. Bailey, Delano R. Freeberg, Dennis Gertenbach, Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, F. Joseph Daugherty
  • Publication number: 20040019119
    Abstract: This invention provides an isolated mixture of higher molecular weight primary aliphatic alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms and having enhanced purity. This invention also provides a process for obtaining the alcohol mixture by extracting a natural product with organic solvents with or without saponification of the natural product. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering total cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels and therefore is effective in treating hypercholesterolemia. The composition may be used to reduce the risk of coronary heart disease, to inhibit the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis), and can be used as an anti-inflammatory and anti-thrombotic agent. The composition also possesses neurotrophic properties and is useful for improving male sexual activity.
    Type: Application
    Filed: July 18, 2003
    Publication date: January 29, 2004
    Inventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez, Dean P. Stull, Steven L. Richheimer, Rebecca L. Nichols, Rod Lenoble
  • Patent number: 6638555
    Abstract: A method of preparing storage-stable, citrus-flavored compositions containing comprising citral or a citral derivative as the flavoring agent and a plant extract as the stabilizing agent. The plant extract inhibits the formation of p-methylacetophenone, thereby preventing the development of off-flavors and off odors and increasing the shelf life of the composition.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: October 28, 2003
    Assignee: Hauser, Inc.
    Inventors: Virginia R. Bank, David T. Bailey, Johan T. van Leersum
  • Publication number: 20030149252
    Abstract: This invention provides a process for the preparation of compositions enriched in total phenols from a crude plant extract. The process includes a novel column purification step using a brominated polystyrene resin. This invention also includes compositions enriched in total phenols. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols and having HPLC chromatograms substantially as set forth in FIGS. 10-13. This invention encompasses methods of using the total phenol-enriched compositions for treating warm-blooded animals, including humans, infected with paramyxovaridae such as respiratory syncytial virus, orthomyoxovaridae such as influenza A, B, and C, parainfluenza, Herpes viruses such as HSV-1 and HSV-2, and Flaviviruses such as West Nile Virus, and for treating inflammation such as caused by arthritis, stress and digestive disease.
    Type: Application
    Filed: November 22, 2002
    Publication date: August 7, 2003
    Inventors: Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, David T. Bailey, Rebecca L. Nichols, F. Joseph Daugherty, Delano R. Freeberg
  • Publication number: 20030138537
    Abstract: The present invention provides an improved process for preparing a water-soluble extract containing one or more naturally occurring antioxidants (from plant materials from the Labiatae family. The process produces an extract that is essentially odorless, flavorless and colorless when used at a concentration between about 5 and 1000 ppm.
    Type: Application
    Filed: December 19, 2001
    Publication date: July 24, 2003
    Inventors: David T. Bailey, Rebecca L. Nichols, Steven L. Richheimer
  • Patent number: 6596776
    Abstract: The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 20 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from a natural product, such as beeswax with and without saponification of the natural product. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels so that it is effective in treating hypercholesterolemia.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: July 22, 2003
    Assignee: Hauser, Inc.
    Inventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez, Dean P. Stull, Steven L. Richheimer, Rebecca L. Nichols, Rod Lenoble
  • Publication number: 20030096876
    Abstract: The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 20 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from a natural product, such as beeswax with and without saponification of the natural product. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels so that it is effective in treating hypercholesterolemia.
    Type: Application
    Filed: April 25, 2002
    Publication date: May 22, 2003
    Inventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez, Dean P. Stull, Steven L. Richheimer, Rebecca L. Nichols, Rod Lenoble
  • Patent number: 6444233
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: September 3, 2002
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • Publication number: 20020099099
    Abstract: The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 20 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from a natural product, such as beeswax with and without saponification of the natural product. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol levels so that it is effective in treating hypercholesterolemia.
    Type: Application
    Filed: September 7, 2001
    Publication date: July 25, 2002
    Inventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez, Dean P. Stull, Steven L. Richheimer, Rebecca L. Nichols, Rod Lenoble
  • Publication number: 20020098269
    Abstract: A method of preparing storage-stable, citrus-flavored compositions comprising citral or a citral derivative as the flavoring agent and a plant extract as the stabilizing agent. The plant extract inhibits the formation of p-methylacetophenone, thereby preventing the development of off-flavors and off odors and increasing the shelf life of the composition.
    Type: Application
    Filed: October 19, 2001
    Publication date: July 25, 2002
    Applicant: J. van Leersum; D. Bailey and V. Bank
    Inventors: Virginia R. Bank, David T. Bailey, Johan T. van Leersum
  • Publication number: 20020082459
    Abstract: The process of the present invention relates to the isolation and purification of both a natural mixed carotenoid product and an all-trans-&bgr;-carotene product from various different biomass sources, preferably from algae of the genus Dunaliella. More particularly, the present invention relates to a single solvent process whereby both natural and colorant products lie along the same process line. The nutritional product contains the natural array of carotenes and xanthophylls found in the plant material, while the colorant product contains primarily trans-&bgr;-carotene.
    Type: Application
    Filed: November 16, 2001
    Publication date: June 27, 2002
    Inventors: David T. Bailey, Randall J. Daughenbaugh, Robert Arslanian, Leonard A. Kaufmann, Steven L. Richheimer, Zhengjie Z. Liu, James M. Piffarerio, Chris J. Kurtz
  • Publication number: 20020058713
    Abstract: The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 20 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from a natural product, such as beeswax with and without saponification of the natural product. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol in LDL-C levels so that it is effective in treating hypercholesterolemia. Consequently the composition may be used to reduce the risk of coronary heart disease, to inhibit the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis) and also to act as an anti-inflammatory and anti-thrombotic agent.
    Type: Application
    Filed: April 27, 2001
    Publication date: May 16, 2002
    Inventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez
  • Publication number: 20020055471
    Abstract: This invention includes both a one-column process and a two-column process for the preparation of compositions enriched for anthocyanins from a crude plant extract. Both processes include a novel column purification step using a brominated polystyrene resin. This invention also includes extracts enriched for anthocyanins.
    Type: Application
    Filed: August 30, 2001
    Publication date: May 9, 2002
    Inventors: David T. Bailey, Delano R. Freeberg, Dennis Gertenbach, Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, F. Joseph Daugherty
  • Patent number: 6306450
    Abstract: Storage-stable, citrus-flavored compositions comprising citral or a citral derivative as the flavoring agent and a plant extract as the stabilizing agent. The plant extract inhibits the formation of p-methylacetophenone, thereby preventing the development of off-flavors and off odors, and increasing the shelf life of the composition.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: October 23, 2001
    Assignee: Hauser, Inc.
    Inventors: Virginia R. Bank, David T. Bailey, Johan T. van Leersum
  • Patent number: 6210679
    Abstract: The process of the present invention relates to the isolation and purification of caffeine-free mixtures catechins from various different biomass sources, preferably from green tea leaves. More particularly, the present invention relates to a four-step process whereby highly pure, caffeine-free EGCG is isolated in high yields. These catechins may be used in pharmaceutical, nutraceutical and cosmetic products.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: April 3, 2001
    Assignee: Hauser, Inc.
    Inventors: David T. Bailey, Ralph L. Yuhasz, BoLin Zheng
  • Patent number: 6132726
    Abstract: In general the present invention relates to a process for the removal of undesireable compounds or residues from an extract which are more polar or less polar than the desired target compound. The preferred embodiment of the present invention is a three step process and is described in detail below. The first step includes contacting a plant material that contains the desired target compound(s) with a solvent, thus producing a crude extract containing a mixture of compounds that includes, in addition to the undesireable residues, the desired target compound(s). The second step involves passing the crude extract through a series of columns containing an absorbent that retards the movement of the undesireable compounds, while allowing the desired compounds to pass. The third and final step involves drying the eluant product to achieve a final product.
    Type: Grant
    Filed: October 21, 1998
    Date of Patent: October 17, 2000
    Assignee: Hauser, Inc.
    Inventors: Randall J. Daughenbaugh, David T. Bailey, William R. Gamble, Dennis D. Gertenbach
  • Patent number: 5908650
    Abstract: An improved pigment composition containing an anthocyanin pigment and a pigment-improving agent selected from the group consisting of flavonoid glycuronides, flavonoid glucuronides, and caffeic acid derivatives. The pigment-improving agents deepen and improve the intensity of the anthocyanin pigment and increase its stability in the presence of light, heat and/or pH.
    Type: Grant
    Filed: October 20, 1995
    Date of Patent: June 1, 1999
    Assignee: Hauser, Inc.
    Inventors: Rod Lenoble, Steven L. Richheimer, Virginia R. Bank, David T. Bailey
  • Patent number: 5859293
    Abstract: A process for the extraction and isolation of concentrated carnosic acid from plant matter of the Labiatae family including contacting the plant matter with a water-miscible solvent to form a plant extract and adjusting the pH of the plant extract to a level between 7 and 10 while adding water in an amount sufficient to cause precipitation of impurities while retaining the carnosic acid salt in solution. The impurities are separated and the remaining aqueous solution is acidified to precipitate a highly purified carnosic acid product which is essentially odorless, flavorless and colorless.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: January 12, 1999
    Assignee: Hauser, Inc.
    Inventors: David T. Bailey, Steven L. Richheimer, Virginia R. Bank, Benjamin T. King
  • Patent number: 5679806
    Abstract: The present invention relates to a process for the isolation and purification of isoflavones from a number of different biomass sources. More particularly, the present invention relates to a three-step process whereby a biomass containing isoflavones with a solvent thereby forming an extract that is subsequently fractionated using a reverse phase matrix in combination with a step gradient elution, wherein the resulting fractions eluted from the column contain specific isoflavones that are later crystallized. The purified isoflavone glycosides may then be hydrolyzed to their respective aglycone.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: October 21, 1997
    Assignee: Hauser, Inc.
    Inventors: BoLin Zheng, John A. Yegge, David T. Bailey, James L. Sullivan