Patents by Inventor David Walsh

David Walsh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040260686
    Abstract: A server for facilitating a vendor showcase system, wherein the server communicates with clients via a distributed computing network, and wherein the server includes a memory storing an instruction set and vendor data related to a plurality of vendors. The server also includes a processor for running the instruction set, the processor being in communication with the memory and the distributed computing network. The processor is operative to (i) sort the vendor data based upon category, (ii) receive criteria related to a request for information, and (iii) provide a display of the vendor data for a pre-selected number of vendors based upon the criteria, wherein the display of the vendor data is presented in a flat manner. The processor may be further operative to compile return on investment statistics based upon user traffic and viewing at the display.
    Type: Application
    Filed: April 1, 2004
    Publication date: December 23, 2004
    Inventors: James Woodroffe, David Walsh, Michael Bulat
  • Publication number: 20040258782
    Abstract: The present invention provides a process for an industrial scale extraction and purification of xanthophylls (e.g., lutein and zeaxanthin) from plant material (e.g., alfalfa or other leafy green crops having high levels of chlorophyll). The process involves harvesting lutein rich alfalfa, extracting an oleoresin from the alfalfa leaves, saponifying the oleoresin, extracting and extracting lutein using a series of solvent extractions specific for oleoresin obtained from alfalfa or other leafy green plants.
    Type: Application
    Filed: October 29, 2003
    Publication date: December 23, 2004
    Inventors: Mark Hoffman, David Baugh, Michael Ahern, David Walsh
  • Publication number: 20040254181
    Abstract: Derivatives of 9-deazaguanine are prepared by reacting an aldehyde or ketone with a dialkylaminomalonate to form the corresponding enamine. The enamine is then reacted with a base to form a cyclic pyrrole. The cyclic pyrrole is reacted with an urea compound or a derivative of carbamimidoic acid to provide a protected guanidino compound. The guanidino is converted to the desired 9-deazaguanine derivative by reacting with trifluoracetic acid or with an alkoxide or hydroxide followed by neutralization with an acid.
    Type: Application
    Filed: June 29, 2004
    Publication date: December 16, 2004
    Applicant: BioCryst Pharmaceuticals, Inc.
    Inventors: Arthur J. Elliott, David A. Walsh, Philip E. Morris
  • Publication number: 20040176475
    Abstract: The present invention provides a process for an industrial scale extraction and purification of xanthophylls (e.g., lutein and zeaxanthin) from plant material (e.g., alfalfa or other leafy green crops having high levels of chlorophyll). The process involves harvesting lutein rich alfalfa, extracting an oleoresin from the alfalfa leaves, saponifying the oleoresin, extracting and extracting lutein using a series of solvent extractions specific for oleoresin obtained from alfalfa or other leafy green plants.
    Type: Application
    Filed: October 17, 2003
    Publication date: September 9, 2004
    Inventors: Mark Hoffman, David Baugh, Michael Ahern, David Walsh
  • Patent number: 6514277
    Abstract: A multitasking optical fiber probe for collecting dosimeter information from more than one position in a sample. The basic principle of the present invention involves using one or more different sensor zones along the length of the fiber each with a different photoactive constituent having a sufficiently unique emission spectra (spectral or temporal) to enable deconvolution of the emission spectra by the computer and therefore correlation of the detected parameter with the position of the sensor zone along the length of the optical fiber. In the broadest form of the invention the probe is embodied by only one sensor zone located at some point along the length of the fiber spaced away from the end face of the fiber.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: February 4, 2003
    Assignee: Photonics Research Ontario
    Inventors: Lothar Lilge, David Walsh
  • Patent number: 6255776
    Abstract: An electroluminescent display includes thin conductive strips on a phosphor-deposited area. One aspect of the invention is directed to a device including a dielectric carrier supporting a first conductive bus connecting to first conductors and a second conductive bus connecting to second conductors. The first and second conductors are arranged in close proximity to one another, so that a phosphor-based carrier can be located therebetween to permit an electric field set up by a voltage applied between the first and second conductors to generate light via the phosphors. A dielectric layer disposed between the conductors enhances the brightness of the light generated. The electroluminescent display can be incorporated as part of a mirror or liquid crystal device.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: July 3, 2001
    Assignee: Phillips Plastics Corporation
    Inventors: Francis Peterson, David Walsh
  • Patent number: 6249800
    Abstract: Apparatus and accompanying methods for use preferably in a multi-system shared data (sysplex) environment (100), wherein each system (110) provides one or more servers (115), for dynamically and adaptively assigning and balancing new work and for new session requests, among the servers in the sysplex, in view of attendant user-defined business importance of these requests and available sysplex resource capacity so as to meet overall business goals. Specifically, systems and servers are categorized into two classes: eligible, i.e., goal-oriented servers running under a policy and for which capacity information is currently available, and candidate, i.e., servers which lack capacity information.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 19, 2001
    Assignee: International Business Machines Corporartion
    Inventors: Jeffrey David Aman, David Bruce Emmes, David Walsh Palmieri
  • Patent number: 6196969
    Abstract: A tissue retractor with an adjustable center claw. The retractor includes two pivoted retractor arms. An axially and angularly displaceable, spring biased clamping mechanism is positioned on the pivot axis. In a mounting position, a elongated clamping element aligns with a slot in the center claw. When the center claw is positioned and the clamp moves to its clamping position, the elongated clamping member clamps the center claw in position. The counterfacing surfaces of the center claw and the clamping member are toothed to provide a positive one-way ratchet clamp.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: March 6, 2001
    Assignee: Lab Engineering & Manufacturing, Inc.
    Inventors: Leon W. Bester, David A. Walsh
  • Patent number: 6183330
    Abstract: An electroluminescent display includes thin conductive strips on a phosphor-deposited area. One aspect of the invention is directed to a device including a dielectric carrier supporting a first conductive bus connecting to first conductors and a second conductive bus connecting to second conductors. The first and second conductors are arranged in close proximity to one another, so that a phosphor-based carrier can be located therebetween and thereover to permit an electric field set up by a voltage applied between the first and second conductors to generate light via the phosphor. The device can be incorporated into a circuit board, integrated circuit or other contoured parts.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: February 6, 2001
    Assignee: Phillips Plastics Corporation
    Inventors: Francis Peterson, David Walsh
  • Patent number: 6069583
    Abstract: The invention relates to a navigation system receiver comprising at least two antennas, one of which is a "reference" antenna. A multiplexer multiplexes the signals from the antennas, and a first processor situated downstream from the multiplexer delivers at least one navigation parameter on the basis of the signals from the multiplexer. The receiver includes a second processor having an input receiving in continuous manner signals from the reference antenna to deliver at least one reference signal representative of a position parameter of the reference antenna. Processor means process the signals from the multiplexer while taking account of at least one said reference signal.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: May 30, 2000
    Assignee: Agence Spatiale Europeene
    Inventors: Pierluigi Silvestrin, Peter Daly, David Walsh, Eric Aardoom
  • Patent number: 5650511
    Abstract: Derivatives of 9-deazaguanine are prepared by reacting an aldehyde or ketone with a dialkylaminomalonate to form the corresponding enamine. The enamine is then reacted with a base to form a cyclic pyrrole. The cyclic pyrrole is reacted with an urea compound to provide a protected guanidino compound. The guanidino is converted to the desired 9-deazaguanine derivative by reacting with trifluoracetic acid or with an alkoxide or hydroxide followed by neutralization with an acid.
    Type: Grant
    Filed: December 12, 1995
    Date of Patent: July 22, 1997
    Assignee: BioCryst Pharmaceuticals, Inc.
    Inventors: Arthur J. Elliott, David A. Walsh
  • Patent number: 5602277
    Abstract: A compound of the Formula (I): ##STR1## or pharmaceutically-suitable salts or prodrug forms thereof, wherein: n is 0-1;m is 0;p is 0-1;R.sup.1 is --CO.sub.2 H;R.sup.2 is selected from the group consisting of H, --OH, and --NH.sub.2 ;R.sup.3 is H;R.sup.4 is --C(O)NHR.sup.8 ;R.sup.5 is --NHC(R.sup.6)NH.sub.2R.sup.6 is selected from the group consisting of .dbd.NH, .dbd.NOH, .dbd.NCN, .dbd.O, and .dbd.S; andR.sup.8 is selected from the group consisting of C.sub.1 -C.sub.4 linear or branched alkyl substituted with 0-3 halogens on each carbon.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: February 11, 1997
    Assignee: BioCryst Pharmaceuticals, Inc.
    Inventors: Yarlagadda S. Babu, Pooran Chand, David A. Walsh
  • Patent number: 5273993
    Abstract: Methods of treating chronic arthritis and osteoporosis which utilize both known and novel compounds which would fall under the general formula:(HO)p--A--[--OS(O).sub.2 NR.sup.1 R.sup.2 ].sub.zwherein A encompasses a wide range of values including but not limited to aryl, loweralkyl, cycloalkyl, and carbohydrates including sucrose and fructose; p is equal to the number of unreacted hydroxy groups contained on the molecule and may be zero; z is the number of --OS(O).sub.2 NR.sup.1 R.sup.2 groups and is always at least one; R.sup.1 and R.sup.2 are selected from hydrogen, loweralkyl, carboxy and the like; a novel process for preparing the compounds is provided wherein an appropriate sulfamic acid aryl ester is reacted with a hydroxy substituted A radical which may or may not contain thereon protected carboxyl, amino or hydroxy substituents, in an aprotic solvent containing a tertiary amine base. Pharmaceutical compositions for the treatment of chronic arthritis and osteoporosis are also provided.
    Type: Grant
    Filed: November 19, 1992
    Date of Patent: December 28, 1993
    Assignee: A. H. Robins Company, Incorporated
    Inventors: Young S. Lo, Joseph C. Nolan, William J. Welstead, Jr., David A. Walsh, Dwight A. Shamblee, Ibrahim M. Uwaydah
  • Patent number: 5194446
    Abstract: Methods of treating chronic arthritis and osteoporosis which utilize both known and novel compounds which would fall under the general formula:(HO)p--A--[--OS(O).sub.2 NR.sup.1 R.sup.2 ].sub.zwherein A encompasses a wide range of values including but not limited to aryl, loweralkyl, cycloalkyl, and carbohydrates including sucrose and fructose; p is equal to the number of unreacted hydroxy groups contained on the molecule and may be zero; z is the number of --OS(O).sub.2 NR.sup.1 R.sup.2 groups and is always at least one; R.sup.1 and R.sup.2 are selected from hydrogen, loweralkyl, carboxy and the like; a novel process for preparing the compounds is provided wherein an appropriate sulfamic acid aryl ester is reacted with a hydroxy substituted A radical which may or may not contain thereon protected carboxyl, amino or hydroxy substituents, in an aprotic solvent containing a tertiary amine base. Pharmaceutical compositions for the treatment of chronic arthritis and osteoporosis are also provided.
    Type: Grant
    Filed: July 24, 1991
    Date of Patent: March 16, 1993
    Assignee: A. H. Robins Company, Incorporated
    Inventors: Young S. Lo, Joseph C. Nolan, William J. Welstead, Jr., David A. Walsh, Dwight A. Shamblee, Ibrahim M. Uwaydah
  • Patent number: 5086055
    Abstract: A method of treating allergic disorders and pharmaceutical compositions therefore are disclosed for a series of 5-[(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone derivatives of Formula I. These compounds are useful in inhibiting Type I allergic ##STR1## responses in a living animal and thus can be used to treat allergic phenomena such as asthma, rhinitis, atopic dermatitis, chronic hives, allergic conjunctivitis and the like.
    Type: Grant
    Filed: December 24, 1990
    Date of Patent: February 4, 1992
    Assignee: A. H. Robins Company, Incorporated
    Inventors: David A. Walsh, John M. Yanni
  • Patent number: 5070087
    Abstract: A method of treating cardiac dysfunction, the effects of histamine, and gastric secretion excesses with aryl(alkyl and alkylene)-N-[(phenoxy and phenythio)alkyl]aminoheterocyclics corresponding to the formula: ##STR1## wherein Ar is phenyl or substituted phenyl; R is phenyl, substituted phenyl, pyridinyl or cycloalkyl; A is hydrogen, hydroxy, cyano, amido and amino; Q is --CH.sub.2 --, --CH--, or --CHOH--; d and n are zero or one and the dotted lines form double bonds consistent with the valence of carbon; p is zero, one or two; m is one to six inclusive; B is oxygen, nitrogen, sulfur, sulfinyl or sulfonyl; z is zero or one; l is zero or one; W is hydrogen, loweralkyl, halo, nitro, loweralkoxy or hydroxy; X is hydrogen, loweralkyl, halogen, loweralkoxy or hydroxy; Y is --CH(OH)CH.sub.2 OH, --CH(OH)C(O)OH, --C(O)C(O)OH, --C(O)CH.sub.2 OH,--C(O)C(O)OCH.sub.3, --C(O)C(O)OC.sub.2 H.sub.5, --CH.sub.2 C(O)OC.sub.2 H.sub.5, --CH(OH)C(O)OCH.sub.3, --CH(OH)C(O)OC.sub.2 H.sub.5 or --C(O)CH.sub.2 OC(O)CH.sub.
    Type: Grant
    Filed: May 8, 1989
    Date of Patent: December 3, 1991
    Assignee: A. H. Robins Company, Incorporated
    Inventors: Lina C. Teng, David A. Walsh, James R. Shanklin, Jr.
  • Patent number: 5063235
    Abstract: Novel compounds of the formula: ##STR1## are disclosed wherein Ar and Ar.sup.1 are phenyl, sustituted phenyl or pyridinyl, "alk" is a C.sub.1 -C.sub.12 straight or branched hydrocarbon chain, and R is H, loweralkylcarbonyl, arylcarbonyl, or aminocarbonyl where the amino is unsubstituted or substituted by one or two groups selected from loweralkyl or aryl. The compounds of this invention are useful in the treatment of allergic disorders.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: November 5, 1991
    Assignee: A. H. Robins Company, Inc.
    Inventor: David A. Walsh
  • Patent number: 5061720
    Abstract: Disclosed are novel substituted 4-thiazolidinone derivatives having cyclooxygenase and 5-lipoxygenase inhibiting properties and which are topical antiinflammatory agents for inflammed conditions of the skin having the formula: ##STR1## wherein R is hydrogen or loweralkyl; R.sup.1 is loweralkyl or aryl; X is --(CH.sub.2)-aryl, --O--(CH.sub.2).sub.0-3 -aryl, --C(O)(CH.sub.2).sub.0-3 -aryl, --CH(OH)--(CH.sub.2).sub.0-3 -aryl or 3,4 ##STR2## (to form naphthyl ring); aryl is phenyl, substituted phenyl, or 2,3 or 4 pyridyl; W is oxygen; Q is -(alk.sup.1).sub.0-1 --(O).sub.0-1 --(B).sub.0-1 --(alk.sup.2).sub.0-1 --[C(O)Z].sub.0-1 ; B is ##STR3## Z is OR.sup.3 or NR.sup.4 R.sup.5 where R.sup.3 is hydrogen, loweralkyl, or a pharmaceutically acceptable metal cation, R.sup.4 and R.sup.5 are hydrogen or loweralkyl; alk.sup.1 and alk.sup.
    Type: Grant
    Filed: September 13, 1989
    Date of Patent: October 29, 1991
    Assignee: A. H. Robins Company, Inc.
    Inventors: David A. Walsh, Ibrahim M. Uwaydah
  • Patent number: 5057524
    Abstract: Novel compounds useful in the treatment of allergic disorders and having the formula: ##STR1## where Ar and Ar.sup.1 are pyridinyl, phenyl, or substituted phenyl and where Y is --OH,--O.sup..crclbar. M.sup..sym. m,--O--loweralkyl, --O--Aryl, or NR.sup.1 R.sup.2 (R.sup.1, R.sup.2 .dbd.H, loweralkyl, aryl) are herein disclosed.
    Type: Grant
    Filed: February 8, 1990
    Date of Patent: October 15, 1991
    Assignee: A. H. Robins Company Incorporated
    Inventor: David A. Walsh
  • Patent number: 5025031
    Abstract: Herein disclosed is a method of treating convulsions with a pharmaceutical composition containing a compound of the formula:(HO).sub.p --A--[OSO.sub.2 NR.sup.1 R.sup.2 ].sub.zwhere A is an aryl, arylalkyl, or aryloxyalkyl group and is substituted on 1 or more carbon atoms with a sulfamate group (--OSO.sub.2 NR.sup.1 R.sup.2) wherein R.sup.1 and R.sup.2, same or different, are hydrogen or loweralkyl wherein p is 0 or 1 and is the number of untreated hydroxyl groups and z is 1 or 2 and is the number of --OS(O.sub.2)NR.sup.1 R.sup.2 groups. Aryl is selected from phenyl, substituted phenyl, pyridinyl, naphthyl, quinolinyl, and the like. Phenyl substituents are selected from hydrogen, halo, hydroxy, phenyl, phenoxy, benzoyl, loweralkyl, loweralkoxy, carboxy, amino, loweralkylamino, diloweralkylamino, acetamido, cyano, nitro, loweralkoxycarboyl, aminosulfonyl, imidazolyl, triazolyl, and the like. Novel compounds not previously disclosed are also described.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: June 18, 1991
    Assignee: A. H. Robins Co., Inc.
    Inventors: Young S. Lo, David A. Walsh, Ibrahim M. Uwaydah