Patents by Inventor Denise Hilfiker-Klein

Denise Hilfiker-Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSING AND TREATING PERIPARTUM CARDIOMYOPATHY THROUGH THE LEVEL OF PLASMINOGEN ACTIVATOR INHIBITOR
    Publication number: 20180246124
    Abstract: The present invention relates to a method for identifying a subject, which has peripartum cardiomyopathy (PPCM) or which has a risk for developing PPCM, wherein the method comprises analyzing the amount and/or activity of plasminogen activator inhibitor-1 (PAI-1); and/or the genotype of the PAI-1 gene. The invention also relates to an inhibitor of PAI-1 for use in the treatment of PPCM. Also a method of treating PPCM in a subject in need of such a treatment, wherein said method comprises administering to said subject an effective amount of an inhibitor of PAI-1 is comprised in the present invention. Moreover, the present invention further relates to the use of a binding molecule for identifying a subject, which has PPCM or which has a risk for developing PPCM, wherein said binding molecule specifically binds to PAI-1.
    Type: Application
    Filed: September 8, 2016
    Publication date: August 30, 2018
    Applicant: Medizinische Hochschule Hannover
    Inventors: Denise Hilfiker-Klein, Justus Nonhoff