Patents by Inventor Dennis L Kolson

Dennis L Kolson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING HIV-ASSOCIATED COGNITIVE DYSFUNCTION
    Publication number: 20170333450
    Abstract: The present invention provides methods comprising treating and/or preventing cognitive dysfunction in subjects infected with HIV by administering an antioxidant inflammation modulator (AIM). The present invention also provides for methods for treating and/or preventing an HIV-associated neurocognitive disorder by contacting peripheral blood monocytes of an HIV+subject with an AIM.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 23, 2017
    Inventors: Andrew Levine, Dimitrios Vatakis, Stefan Horvath, Dennis L. Kolson
  • Method for the production of antibodies that bind to multiple membrane spanning proteins
    Patent number: 8680244
    Abstract: Enveloped virus vectors are described which comprise a cellular virus receptor protein and which are capable of fusing with a cell which comprises a viral envelope protein to which the cellular virus receptor protein is cognate. Enveloped virus vectors comprising a plurality of cellular virus receptor proteins are also described. Methods for making the enveloped virus vectors are described, as are methods of using the enveloped virus vectors. The invention further relates to a lipoparticle comprising a membrane spanning protein, and the lipoparticle can be attached to a sensor surface. The invention relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: March 25, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Robert Doms, Joseph Rucker, Trevor L Hoffman, Paul Bates, James A Hoxie, Michael J Endres, John Balliet, Dennis L Kolson
  • Method for the preparation of virus-like particles (VLPS) comprising heterologous multiple membrane spanning proteins
    Patent number: 8158130
    Abstract: Enveloped virus vectors are described which comprise a cellular virus receptor protein and which are capable of fusing with a cell which comprises a viral envelope protein to which the cellular virus receptor protein is cognate. Enveloped virus vectors comprising a plurality of cellular virus receptor proteins are also described. Methods for making the enveloped virus vectors are described, as are methods of using the enveloped virus vectors. The invention further relates to a lipoparticle comprising a membrane spanning protein, and the lipoparticle can be attached to a sensor surface. The invention relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.
    Type: Grant
    Filed: March 9, 2010
    Date of Patent: April 17, 2012
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Robert W Doms, Joseph Rucker, Trevor L Hoffman, Paul Bates, James A Hoxie, Michael J Endres, John Balliet, Dennis L Kolson